BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

191 related articles for article (PubMed ID: 28213125)

  • 1. Reduced bioavailable manganese causes striatal urea cycle pathology in Huntington's disease mouse model.
    Bichell TJV; Wegrzynowicz M; Tipps KG; Bradley EM; Uhouse MA; Bryan M; Horning K; Fisher N; Dudek K; Halbesma T; Umashanker P; Stubbs AD; Holt HK; Kwakye GF; Tidball AM; Colbran RJ; Aschner M; Neely MD; Di Pardo A; Maglione V; Osmand A; Bowman AB
    Biochim Biophys Acta Mol Basis Dis; 2017 Jun; 1863(6):1596-1604. PubMed ID: 28213125
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Brain urea increase is an early Huntington's disease pathogenic event observed in a prodromal transgenic sheep model and HD cases.
    Handley RR; Reid SJ; Brauning R; Maclean P; Mears ER; Fourie I; Patassini S; Cooper GJS; Rudiger SR; McLaughlan CJ; Verma PJ; Gusella JF; MacDonald ME; Waldvogel HJ; Bawden CS; Faull RLM; Snell RG
    Proc Natl Acad Sci U S A; 2017 Dec; 114(52):E11293-E11302. PubMed ID: 29229845
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Altered manganese homeostasis and manganese toxicity in a Huntington's disease striatal cell model are not explained by defects in the iron transport system.
    Williams BB; Kwakye GF; Wegrzynowicz M; Li D; Aschner M; Erikson KM; Bowman AB
    Toxicol Sci; 2010 Sep; 117(1):169-79. PubMed ID: 20547568
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Untargeted metabolic profiling identifies interactions between Huntington's disease and neuronal manganese status.
    Kumar KK; Goodwin CR; Uhouse MA; Bornhorst J; Schwerdtle T; Aschner M; McLean JA; Bowman AB
    Metallomics; 2015 Feb; 7(2):363-70. PubMed ID: 25599126
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A novel manganese-dependent ATM-p53 signaling pathway is selectively impaired in patient-based neuroprogenitor and murine striatal models of Huntington's disease.
    Tidball AM; Bryan MR; Uhouse MA; Kumar KK; Aboud AA; Feist JE; Ess KC; Neely MD; Aschner M; Bowman AB
    Hum Mol Genet; 2015 Apr; 24(7):1929-44. PubMed ID: 25489053
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Specific caspase interactions and amplification are involved in selective neuronal vulnerability in Huntington's disease.
    Hermel E; Gafni J; Propp SS; Leavitt BR; Wellington CL; Young JE; Hackam AS; Logvinova AV; Peel AL; Chen SF; Hook V; Singaraja R; Krajewski S; Goldsmith PC; Ellerby HM; Hayden MR; Bredesen DE; Ellerby LM
    Cell Death Differ; 2004 Apr; 11(4):424-38. PubMed ID: 14713958
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Reduced Expression of Foxp1 as a Contributing Factor in Huntington's Disease.
    Louis Sam Titus ASC; Yusuff T; Cassar M; Thomas E; Kretzschmar D; D'Mello SR
    J Neurosci; 2017 Jul; 37(27):6575-6587. PubMed ID: 28550168
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Acute manganese treatment restores defective autophagic cargo loading in Huntington's disease cell lines.
    Bryan MR; O'Brien MT; Nordham KD; Rose DIR; Foshage AM; Joshi P; Nitin R; Uhouse MA; Di Pardo A; Zhang Z; Maglione V; Aschner M; Bowman AB
    Hum Mol Genet; 2019 Nov; 28(22):3825-3841. PubMed ID: 31600787
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Impaired XK recycling for importing manganese underlies striatal vulnerability in Huntington's disease.
    Chhetri G; Ke Y; Wang P; Usman M; Li Y; Sapp E; Wang J; Ghosh A; Islam MA; Wang X; Boudi A; DiFiglia M; Li X
    J Cell Biol; 2022 Oct; 221(10):. PubMed ID: 36099524
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Huntington's disease associated resistance to Mn neurotoxicity is neurodevelopmental stage and neuronal lineage dependent.
    Joshi P; Bodnya C; Ilieva I; Neely MD; Aschner M; Bowman AB
    Neurotoxicology; 2019 Dec; 75():148-157. PubMed ID: 31545971
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel high-throughput assay to assess cellular manganese levels in a striatal cell line model of Huntington's disease confirms a deficit in manganese accumulation.
    Kwakye GF; Li D; Bowman AB
    Neurotoxicology; 2011 Oct; 32(5):630-9. PubMed ID: 21238486
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Manganese and the Insulin-IGF Signaling Network in Huntington's Disease and Other Neurodegenerative Disorders.
    Bryan MR; Bowman AB
    Adv Neurobiol; 2017; 18():113-142. PubMed ID: 28889265
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Striatal Cholesterol Precursors Are Altered with Age in Female Huntington's Disease Model Mice.
    Pfalzer AC; Wages PA; Porter NA; Bowman AB
    J Huntingtons Dis; 2019; 8(2):161-169. PubMed ID: 30958310
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Selective reduction of striatal mature BDNF without induction of proBDNF in the zQ175 mouse model of Huntington's disease.
    Ma Q; Yang J; Li T; Milner TA; Hempstead BL
    Neurobiol Dis; 2015 Oct; 82():466-477. PubMed ID: 26282324
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ectopic expression of the striatal-enriched GTPase Rhes elicits cerebellar degeneration and an ataxia phenotype in Huntington's disease.
    Swarnkar S; Chen Y; Pryor WM; Shahani N; Page DT; Subramaniam S
    Neurobiol Dis; 2015 Oct; 82():66-77. PubMed ID: 26048156
    [TBL] [Abstract][Full Text] [Related]  

  • 16. AMPK-α1 functions downstream of oxidative stress to mediate neuronal atrophy in Huntington's disease.
    Ju TC; Chen HM; Chen YC; Chang CP; Chang C; Chern Y
    Biochim Biophys Acta; 2014 Sep; 1842(9):1668-80. PubMed ID: 24946181
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dysregulation of C/EBPalpha by mutant Huntingtin causes the urea cycle deficiency in Huntington's disease.
    Chiang MC; Chen HM; Lee YH; Chang HH; Wu YC; Soong BW; Chen CM; Wu YR; Liu CS; Niu DM; Wu JY; Chen YT; Chern Y
    Hum Mol Genet; 2007 Mar; 16(5):483-98. PubMed ID: 17213233
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Adenovirus vector-based in vitro neuronal cell model for Huntington's disease with human disease-like differential aggregation and degeneration.
    Dong X; Zong S; Witting A; Lindenberg KS; Kochanek S; Huang B
    J Gene Med; 2012 Jul; 14(7):468-81. PubMed ID: 22700462
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Disease-toxicant interactions in manganese exposed Huntington disease mice: early changes in striatal neuron morphology and dopamine metabolism.
    Madison JL; Wegrzynowicz M; Aschner M; Bowman AB
    PLoS One; 2012; 7(2):e31024. PubMed ID: 22363539
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutant huntingtin causes context-dependent neurodegeneration in mice with Huntington's disease.
    Yu ZX; Li SH; Evans J; Pillarisetti A; Li H; Li XJ
    J Neurosci; 2003 Mar; 23(6):2193-202. PubMed ID: 12657678
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.