BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

92 related articles for article (PubMed ID: 28214231)

  • 1. Mechanisms of action and structure-activity relationships of cytotoxic flavokawain derivatives.
    Thieury C; Lebouvier N; Le Guével R; Barguil Y; Herbette G; Antheaume C; Hnawia E; Asakawa Y; Nour M; Guillaudeux T
    Bioorg Med Chem; 2017 Mar; 25(6):1817-1829. PubMed ID: 28214231
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effects of the kava chalcone flavokawain A differ in bladder cancer cells with wild-type versus mutant p53.
    Tang Y; Simoneau AR; Xie J; Shahandeh B; Zi X
    Cancer Prev Res (Phila); 2008 Nov; 1(6):439-51. PubMed ID: 19138991
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice.
    Zi X; Simoneau AR
    Cancer Res; 2005 Apr; 65(8):3479-86. PubMed ID: 15833884
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Flavokawain B inhibits growth of human squamous carcinoma cells: Involvement of apoptosis and cell cycle dysregulation in vitro and in vivo.
    Lin E; Lin WH; Wang SY; Chen CS; Liao JW; Chang HW; Chen SC; Lin KY; Wang L; Yang HL; Hseu YC
    J Nutr Biochem; 2012 Apr; 23(4):368-78. PubMed ID: 21543203
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cyclization of flavokawain B reduces its activity against human colon cancer cells.
    Palko-Łabuz A; Kostrzewa-Susłow E; Janeczko T; Środa-Pomianek K; Poła A; Uryga A; Michalak K
    Hum Exp Toxicol; 2020 Mar; 39(3):262-275. PubMed ID: 31640425
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In vitro Toxicity and in vivo Immunomodulatory Effects of Flavokawain A and Flavokawain B in Balb/C Mice.
    Abu N; Mohameda NE; Tangarajoo N; Yeap SK; Akhtar MN; Abdullah MP; Omar AR; Alitheen NB
    Nat Prod Commun; 2015 Jul; 10(7):1199-202. PubMed ID: 26411010
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis and preliminary structure-activity relationship investigation of nitrogen-containing chalcone derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors: a further study based on Flavokawain B Mannich base derivatives.
    Liu H; Fan H; Gao X; Huang X; Liu X; Liu L; Zhou C; Tang J; Wang Q; Liu W
    J Enzyme Inhib Med Chem; 2016 Aug; 31(4):580-9. PubMed ID: 26186269
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Flavokawain derivative FLS induced G2/M arrest and apoptosis on breast cancer MCF-7 cell line.
    Ali NM; Akhtar MN; Ky H; Lim KL; Abu N; Zareen S; Ho WY; Alan-Ong HK; Tan SW; Alitheen NB; Ismail JB; Yeap SK; Kamarul T
    Drug Des Devel Ther; 2016; 10():1897-907. PubMed ID: 27358555
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and biological evaluation of novel pyrazolic chalcone derivatives as novel hepatocellular carcinoma therapeutics.
    Hawash MM; Kahraman DC; Eren F; Cetin Atalay R; Baytas SN
    Eur J Med Chem; 2017 Mar; 129():12-26. PubMed ID: 28219046
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In vivo antitumor and antimetastatic effects of flavokawain B in 4T1 breast cancer cell-challenged mice.
    Abu N; Mohamed NE; Yeap SK; Lim KL; Akhtar MN; Zulfadli AJ; Kee BB; Abdullah MP; Omar AR; Alitheen NB
    Drug Des Devel Ther; 2015; 9():1401-17. PubMed ID: 25834398
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Flavokawain B induced cytotoxicity in two breast cancer cell lines, MCF-7 and MDA-MB231 and inhibited the metastatic potential of MDA-MB231 via the regulation of several tyrosine kinases In vitro.
    Abu N; Akhtar MN; Yeap SK; Lim KL; Ho WY; Abdullah MP; Ho CL; Omar AR; Ismail J; Alitheen NB
    BMC Complement Altern Med; 2016 Feb; 16():86. PubMed ID: 26922065
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Flavokawain B induces apoptosis of human oral adenoid cystic cancer ACC-2 cells via up-regulation of Bim and down-regulation of Bcl-2 expression.
    Zhao X; Chao YL; Wan QB; Chen XM; Su P; Sun J; Tang Y
    Can J Physiol Pharmacol; 2011 Dec; 89(12):875-83. PubMed ID: 22115332
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and Anti-cancer Activity of 3-substituted Benzoyl-4-substituted Phenyl-1H-pyrrole Derivatives.
    Zhan X; Qin W; Wang S; Zhao K; Xin Y; Wang Y; Qi Q; Mao Z
    Anticancer Agents Med Chem; 2017; 17(6):821-831. PubMed ID: 27671311
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The chalcone flavokawain B induces G2/M cell-cycle arrest and apoptosis in human oral carcinoma HSC-3 cells through the intracellular ROS generation and downregulation of the Akt/p38 MAPK signaling pathway.
    Hseu YC; Lee MS; Wu CR; Cho HJ; Lin KY; Lai GH; Wang SY; Kuo YH; Kumar KJ; Yang HL
    J Agric Food Chem; 2012 Mar; 60(9):2385-97. PubMed ID: 22324429
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Flavokawain B, a novel chalcone from Alpinia pricei Hayata with potent apoptotic activity: Involvement of ROS and GADD153 upstream of mitochondria-dependent apoptosis in HCT116 cells.
    Kuo YF; Su YZ; Tseng YH; Wang SY; Wang HM; Chueh PJ
    Free Radic Biol Med; 2010 Jul; 49(2):214-26. PubMed ID: 20398749
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of flavonoids on cell proliferation and caspase activation in a human colonic cell line HT29: an SAR study.
    Daskiewicz JB; Depeint F; Viornery L; Bayet C; Comte-Sarrazin G; Comte G; Gee JM; Johnson IT; Ndjoko K; Hostettmann K; Barron D
    J Med Chem; 2005 Apr; 48(8):2790-804. PubMed ID: 15828817
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Flavokawain A inhibits Cytochrome P450 in in vitro metabolic and inhibitory investigations.
    Niu L; Ding L; Lu C; Zuo F; Yao K; Xu S; Li W; Yang D; Xu X
    J Ethnopharmacol; 2016 Sep; 191():350-359. PubMed ID: 27318274
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Isoliquiritigenin induces apoptosis and cell cycle arrest through p53-dependent pathway in Hep G2 cells.
    Hsu YL; Kuo PL; Lin CC
    Life Sci; 2005 Jun; 77(3):279-92. PubMed ID: 15878356
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The investigational Aurora kinase A inhibitor alisertib (MLN8237) induces cell cycle G2/M arrest, apoptosis, and autophagy via p38 MAPK and Akt/mTOR signaling pathways in human breast cancer cells.
    Li JP; Yang YX; Liu QL; Pan ST; He ZX; Zhang X; Yang T; Chen XW; Wang D; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():1627-52. PubMed ID: 25834401
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design and multi-step synthesis of chalcone-polyamine conjugates as potent antiproliferative agents.
    Rioux B; Pouget C; Fidanzi-Dugas C; Gamond A; Laurent A; Semaan J; Pinon A; Champavier Y; Léger DY; Liagre B; Duroux JL; Fagnère C; Sol V
    Bioorg Med Chem Lett; 2017 Sep; 27(18):4354-4357. PubMed ID: 28838697
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.