BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

636 related articles for article (PubMed ID: 28215704)

  • 21. Quantitative detection of DNMT3A R882H mutation in acute myeloid leukemia.
    Berenstein R; Blau IW; Suckert N; Baldus C; Pezzutto A; Dörken B; Blau O
    J Exp Clin Cancer Res; 2015 May; 34(1):55. PubMed ID: 25994761
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Recurrent DNMT3A mutations in patients with myelodysplastic syndromes.
    Walter MJ; Ding L; Shen D; Shao J; Grillot M; McLellan M; Fulton R; Schmidt H; Kalicki-Veizer J; O'Laughlin M; Kandoth C; Baty J; Westervelt P; DiPersio JF; Mardis ER; Wilson RK; Ley TJ; Graubert TA
    Leukemia; 2011 Jul; 25(7):1153-8. PubMed ID: 21415852
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Remethylation of
    Ketkar S; Verdoni AM; Smith AM; Bangert CV; Leight ER; Chen DY; Brune MK; Helton NM; Hoock M; George DR; Fronick C; Fulton RS; Ramakrishnan SM; Chang GS; Petti AA; Spencer DH; Miller CA; Ley TJ
    Proc Natl Acad Sci U S A; 2020 Feb; 117(6):3123-3134. PubMed ID: 31996479
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Functional Analysis of DNMT3A DNA Methyltransferase Mutations Reported in Patients with Acute Myeloid Leukemia.
    Khrabrova DA; Loiko AG; Tolkacheva AA; Cherepanova NA; Zvereva MI; Kirsanova OV; Gromova ES
    Biomolecules; 2019 Dec; 10(1):. PubMed ID: 31861499
    [TBL] [Abstract][Full Text] [Related]  

  • 25. MN1 overexpression is driven by loss of DNMT3B methylation activity in inv(16) pediatric AML.
    Larmonie NSD; Arentsen-Peters TCJM; Obulkasim A; Valerio D; Sonneveld E; Danen-van Oorschot AA; de Haas V; Reinhardt D; Zimmermann M; Trka J; Baruchel A; Pieters R; van den Heuvel-Eibrink MM; Zwaan CM; Fornerod M
    Oncogene; 2018 Jan; 37(1):107-115. PubMed ID: 28892045
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Functional and epigenetic phenotypes of humans and mice with DNMT3A Overgrowth Syndrome.
    Smith AM; LaValle TA; Shinawi M; Ramakrishnan SM; Abel HJ; Hill CA; Kirkland NM; Rettig MP; Helton NM; Heath SE; Ferraro F; Chen DY; Adak S; Semenkovich CF; Christian DL; Martin JR; Gabel HW; Miller CA; Ley TJ
    Nat Commun; 2021 Jul; 12(1):4549. PubMed ID: 34315901
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Persistent DNMT3A mutation burden in DNMT3A mutated adult cytogenetically normal acute myeloid leukemia patients in long-term remission.
    Sun Y; Shen H; Xu T; Yang Z; Qiu H; Sun A; Chen S; Wu D; Xu Y
    Leuk Res; 2016 Oct; 49():102-7. PubMed ID: 27626217
    [TBL] [Abstract][Full Text] [Related]  

  • 28. DNMT3A mutation promotes leukemia development through NAM-NAD metabolic reprogramming.
    Yang X; Wang X; Yang Y; Li Z; Chen Y; Shang S; Wang Y
    J Transl Med; 2023 Jul; 21(1):481. PubMed ID: 37464424
    [TBL] [Abstract][Full Text] [Related]  

  • 29. A DNMT3A mutation common in AML exhibits dominant-negative effects in murine ES cells.
    Kim SJ; Zhao H; Hardikar S; Singh AK; Goodell MA; Chen T
    Blood; 2013 Dec; 122(25):4086-9. PubMed ID: 24167195
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Structural basis for impairment of DNA methylation by the DNMT3A R882H mutation.
    Anteneh H; Fang J; Song J
    Nat Commun; 2020 May; 11(1):2294. PubMed ID: 32385248
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Mutations in DNA methyltransferase (DNMT3A) observed in acute myeloid leukemia patients disrupt processive methylation.
    Holz-Schietinger C; Matje DM; Reich NO
    J Biol Chem; 2012 Sep; 287(37):30941-51. PubMed ID: 22722925
    [TBL] [Abstract][Full Text] [Related]  

  • 32. DNMT3A mutations promote anthracycline resistance in acute myeloid leukemia via impaired nucleosome remodeling.
    Guryanova OA; Shank K; Spitzer B; Luciani L; Koche RP; Garrett-Bakelman FE; Ganzel C; Durham BH; Mohanty A; Hoermann G; Rivera SA; Chramiec AG; Pronier E; Bastian L; Keller MD; Tovbin D; Loizou E; Weinstein AR; Gonzalez AR; Lieu YK; Rowe JM; Pastore F; McKenney AS; Krivtsov AV; Sperr WR; Cross JR; Mason CE; Tallman MS; Arcila ME; Abdel-Wahab O; Armstrong SA; Kubicek S; Staber PB; Gönen M; Paietta EM; Melnick AM; Nimer SD; Mukherjee S; Levine RL
    Nat Med; 2016 Dec; 22(12):1488-1495. PubMed ID: 27841873
    [TBL] [Abstract][Full Text] [Related]  

  • 33. DNMT3A R882 Mutations Predict a Poor Prognosis in AML: A Meta-Analysis From 4474 Patients.
    Yuan XQ; Peng L; Zeng WJ; Jiang BY; Li GC; Chen XP
    Medicine (Baltimore); 2016 May; 95(18):e3519. PubMed ID: 27149454
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Novel impact of the DNMT3A R882H mutation on GSH metabolism in a K562 cell model established by TALENs.
    Yang L; Liu Y; Zhang N; Ding X; Zhang W; Shen K; Huang L; Zhou J; Cui S; Zhu Z; Hu Z; Xiao M
    Oncotarget; 2017 May; 8(18):30395-30409. PubMed ID: 28418922
    [TBL] [Abstract][Full Text] [Related]  

  • 35. DNMT3A R882H mutation promotes acute leukemic cell survival by regulating glycolysis through the NRF2/NQO1 axis.
    Chu X; Zhong L; Dan W; Wang X; Zhang Z; Liu Z; Lu Y; Shao X; Zhou Z; Chen S; Liu B
    Cell Signal; 2023 May; 105():110626. PubMed ID: 36758683
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Therapy-related acute myeloid leukemia developing 14 years after allogeneic hematopoietic stem cell transplantation, from a persistent R882H-DNMT3A mutated clone of patient origin.
    Martín I; Navarro B; Villamón E; Solano C; Serrano A; Calabuig M; Amat P; Domingo F; Abellán R; García F; Olivares MD; Chaves FJ; Tormo M; Hernández-Boluda JC
    Exp Mol Pathol; 2018 Aug; 105(1):139-143. PubMed ID: 30017658
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Epigenetic regulation of GATA2 and its impact on normal karyotype acute myeloid leukemia.
    Celton M; Forest A; Gosse G; Lemieux S; Hebert J; Sauvageau G; Wilhelm BT
    Leukemia; 2014 Aug; 28(8):1617-26. PubMed ID: 24514424
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Epimutations mimic genomic mutations of DNMT3A in acute myeloid leukemia.
    Jost E; Lin Q; Weidner CI; Wilop S; Hoffmann M; Walenda T; Schemionek M; Herrmann O; Zenke M; Brümmendorf TH; Koschmieder S; Wagner W
    Leukemia; 2014 Jun; 28(6):1227-34. PubMed ID: 24280869
    [TBL] [Abstract][Full Text] [Related]  

  • 39. DNA methylation and hydroxymethylation patterns in acute myeloid leukemia patients with mutations in DNMT3A and IDH1/2 and their combinations.
    Šestáková Š; Krejčík Z; Folta A; Cerovská E; Šálek C; Merkerová MD; Pecherková P; Ráčil Z; Mayer J; Cetkovský P; Remešová H
    Cancer Biomark; 2019; 25(1):43-51. PubMed ID: 30988238
    [TBL] [Abstract][Full Text] [Related]  

  • 40. The R882H DNMT3A hot spot mutation stabilizes the formation of large DNMT3A oligomers with low DNA methyltransferase activity.
    Nguyen TV; Yao S; Wang Y; Rolfe A; Selvaraj A; Darman R; Ke J; Warmuth M; Smith PG; Larsen NA; Yu L; Zhu P; Fekkes P; Vaillancourt FH; Bolduc DM
    J Biol Chem; 2019 Nov; 294(45):16966-16977. PubMed ID: 31582562
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 32.