BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

299 related articles for article (PubMed ID: 28218749)

  • 1. Mechanistic basis for the recognition of a misfolded protein by the molecular chaperone Hsp90.
    Oroz J; Kim JH; Chang BJ; Zweckstetter M
    Nat Struct Mol Biol; 2017 Apr; 24(4):407-413. PubMed ID: 28218749
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hsp90 interaction with clients.
    Karagöz GE; Rüdiger SG
    Trends Biochem Sci; 2015 Feb; 40(2):117-25. PubMed ID: 25579468
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The mechanism of Hsp90-induced oligomerizaton of Tau.
    Weickert S; Wawrzyniuk M; John LH; Rüdiger SGD; Drescher M
    Sci Adv; 2020 Mar; 6(11):eaax6999. PubMed ID: 32201713
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complex.
    Oroz J; Chang BJ; Wysoczanski P; Lee CT; Pérez-Lara Á; Chakraborty P; Hofele RV; Baker JD; Blair LJ; Biernat J; Urlaub H; Mandelkow E; Dickey CA; Zweckstetter M
    Nat Commun; 2018 Oct; 9(1):4532. PubMed ID: 30382094
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hsp90 structure and function studied by NMR spectroscopy.
    Didenko T; Duarte AM; Karagöz GE; Rüdiger SG
    Biochim Biophys Acta; 2012 Mar; 1823(3):636-47. PubMed ID: 22155720
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dynamic Aha1 co-chaperone binding to human Hsp90.
    Oroz J; Blair LJ; Zweckstetter M
    Protein Sci; 2019 Sep; 28(9):1545-1551. PubMed ID: 31299134
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mechanistic Asymmetry in Hsp90 Dimers.
    Flynn JM; Mishra P; Bolon DN
    J Mol Biol; 2015 Sep; 427(18):2904-11. PubMed ID: 25843003
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dancing with the Diva: Hsp90-Client Interactions.
    Radli M; Rüdiger SGD
    J Mol Biol; 2018 Sep; 430(18 Pt B):3029-3040. PubMed ID: 29782836
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cross-monomer substrate contacts reposition the Hsp90 N-terminal domain and prime the chaperone activity.
    Street TO; Lavery LA; Verba KA; Lee CT; Mayer MP; Agard DA
    J Mol Biol; 2012 Jan; 415(1):3-15. PubMed ID: 22063096
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hsp90-Tau complex reveals molecular basis for specificity in chaperone action.
    Karagöz GE; Duarte AM; Akoury E; Ippel H; Biernat J; Morán Luengo T; Radli M; Didenko T; Nordhues BA; Veprintsev DB; Dickey CA; Mandelkow E; Zweckstetter M; Boelens R; Madl T; Rüdiger SG
    Cell; 2014 Feb; 156(5):963-74. PubMed ID: 24581495
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Retention of misfolded mutant transthyretin by the chaperone BiP/GRP78 mitigates amyloidogenesis.
    Sörgjerd K; Ghafouri B; Jonsson BH; Kelly JW; Blond SY; Hammarström P
    J Mol Biol; 2006 Feb; 356(2):469-82. PubMed ID: 16376939
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Hsp90 chaperone machinery: conformational dynamics and regulation by co-chaperones.
    Li J; Soroka J; Buchner J
    Biochim Biophys Acta; 2012 Mar; 1823(3):624-35. PubMed ID: 21951723
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The HSP90 chaperone machinery.
    Schopf FH; Biebl MM; Buchner J
    Nat Rev Mol Cell Biol; 2017 Jun; 18(6):345-360. PubMed ID: 28429788
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The Hsp90 Chaperone:
    Lee BL; Rashid S; Wajda B; Wolmarans A; LaPointe P; Spyracopoulos L
    Biochemistry; 2019 Apr; 58(14):1869-1877. PubMed ID: 30869872
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hsp90 regulates tau pathology through co-chaperone complexes in Alzheimer's disease.
    Salminen A; Ojala J; Kaarniranta K; Hiltunen M; Soininen H
    Prog Neurobiol; 2011 Jan; 93(1):99-110. PubMed ID: 21056617
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Biological and structural basis for Aha1 regulation of Hsp90 ATPase activity in maintaining proteostasis in the human disease cystic fibrosis.
    Koulov AV; LaPointe P; Lu B; Razvi A; Coppinger J; Dong MQ; Matteson J; Laister R; Arrowsmith C; Yates JR; Balch WE
    Mol Biol Cell; 2010 Mar; 21(6):871-84. PubMed ID: 20089831
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Biochemical and structural studies of the interaction of Cdc37 with Hsp90.
    Zhang W; Hirshberg M; McLaughlin SH; Lazar GA; Grossmann JG; Nielsen PR; Sobott F; Robinson CV; Jackson SE; Laue ED
    J Mol Biol; 2004 Jul; 340(4):891-907. PubMed ID: 15223329
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Folding or holding?-Hsp70 and Hsp90 chaperoning of misfolded proteins in neurodegenerative disease.
    Rutledge BS; Choy WY; Duennwald ML
    J Biol Chem; 2022 May; 298(5):101905. PubMed ID: 35398094
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Elucidating the mechanism of substrate recognition by the bacterial Hsp90 molecular chaperone.
    Street TO; Zeng X; Pellarin R; Bonomi M; Sali A; Kelly MJ; Chu F; Agard DA
    J Mol Biol; 2014 Jun; 426(12):2393-404. PubMed ID: 24726919
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Co-chaperone Cns1 and the Recruiter Protein Hgh1 Link Hsp90 to Translation Elongation via Chaperoning Elongation Factor 2.
    Schopf FH; Huber EM; Dodt C; Lopez A; Biebl MM; Rutz DA; Mühlhofer M; Richter G; Madl T; Sattler M; Groll M; Buchner J
    Mol Cell; 2019 Apr; 74(1):73-87.e8. PubMed ID: 30876805
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.