BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

387 related articles for article (PubMed ID: 28223512)

  • 21. Loss of tau expression attenuates neurodegeneration associated with α-synucleinopathy.
    Vermilyea SC; Christensen A; Meints J; Singh B; Martell-Martínez H; Karim MR; Lee MK
    Transl Neurodegener; 2022 Jul; 11(1):34. PubMed ID: 35773715
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Up-regulation of SNCA gene expression: implications to synucleinopathies.
    Tagliafierro L; Chiba-Falek O
    Neurogenetics; 2016 Jul; 17(3):145-57. PubMed ID: 26948950
    [TBL] [Abstract][Full Text] [Related]  

  • 23. GBA haploinsufficiency accelerates alpha-synuclein pathology with altered lipid metabolism in a prodromal model of Parkinson's disease.
    Ikuno M; Yamakado H; Akiyama H; Parajuli LK; Taguchi K; Hara J; Uemura N; Hatanaka Y; Higaki K; Ohno K; Tanaka M; Koike M; Hirabayashi Y; Takahashi R
    Hum Mol Genet; 2019 Jun; 28(11):1894-1904. PubMed ID: 30689867
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Viral delivery of a microRNA to Gba to the mouse central nervous system models neuronopathic Gaucher disease.
    Jackson KL; Viel C; Clarke J; Bu J; Chan M; Wang B; Shihabuddin LS; Sardi SP
    Neurobiol Dis; 2019 Oct; 130():104513. PubMed ID: 31233883
    [TBL] [Abstract][Full Text] [Related]  

  • 25. MicroRNA expressing profiles in A53T mutant alpha-synuclein transgenic mice and Parkinsonian.
    Mo M; Xiao Y; Huang S; Cen L; Chen X; Zhang L; Luo Q; Li S; Yang X; Lin X; Xu P
    Oncotarget; 2017 Jan; 8(1):15-28. PubMed ID: 27965467
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Glucocerebrosidase gene therapy prevents α-synucleinopathy of midbrain dopamine neurons.
    Rocha EM; Smith GA; Park E; Cao H; Brown E; Hayes MA; Beagan J; McLean JR; Izen SC; Perez-Torres E; Hallett PJ; Isacson O
    Neurobiol Dis; 2015 Oct; 82():495-503. PubMed ID: 26392287
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Tau is required for progressive synaptic and memory deficits in a transgenic mouse model of α-synucleinopathy.
    Singh B; Covelo A; Martell-Martínez H; Nanclares C; Sherman MA; Okematti E; Meints J; Teravskis PJ; Gallardo C; Savonenko AV; Benneyworth MA; Lesné SE; Liao D; Araque A; Lee MK
    Acta Neuropathol; 2019 Oct; 138(4):551-574. PubMed ID: 31168644
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Tau oligomers mediate α-synuclein toxicity and can be targeted by immunotherapy.
    Gerson JE; Farmer KM; Henson N; Castillo-Carranza DL; Carretero Murillo M; Sengupta U; Barrett A; Kayed R
    Mol Neurodegener; 2018 Mar; 13(1):13. PubMed ID: 29544548
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Altered ceramide metabolism is a feature in the extracellular vesicle-mediated spread of alpha-synuclein in Lewy body disorders.
    Kurzawa-Akanbi M; Tammireddy S; Fabrik I; Gliaudelytė L; Doherty MK; Heap R; Matečko-Burmann I; Burmann BM; Trost M; Lucocq JM; Gherman AV; Fairfoul G; Singh P; Burté F; Green A; McKeith IG; Härtlova A; Whitfield PD; Morris CM
    Acta Neuropathol; 2021 Dec; 142(6):961-984. PubMed ID: 34514546
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Modulation of β-glucocerebrosidase increases α-synuclein secretion and exosome release in mouse models of Parkinson's disease.
    Papadopoulos VE; Nikolopoulou G; Antoniadou I; Karachaliou A; Arianoglou G; Emmanouilidou E; Sardi SP; Stefanis L; Vekrellis K
    Hum Mol Genet; 2018 May; 27(10):1696-1710. PubMed ID: 29547959
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Chronic mild stress accelerates the progression of Parkinson's disease in A53T α-synuclein transgenic mice.
    Wu Q; Yang X; Zhang Y; Zhang L; Feng L
    Exp Neurol; 2016 Nov; 285(Pt A):61-71. PubMed ID: 27637804
    [TBL] [Abstract][Full Text] [Related]  

  • 32. GBA deficiency promotes SNCA/α-synuclein accumulation through autophagic inhibition by inactivated PPP2A.
    Du TT; Wang L; Duan CL; Lu LL; Zhang JL; Gao G; Qiu XB; Wang XM; Yang H
    Autophagy; 2015; 11(10):1803-20. PubMed ID: 26378614
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Silencing of Glucocerebrosidase Gene in
    Abul Khair SB; Dhanushkodi NR; Ardah MT; Chen W; Yang Y; Haque ME
    Front Neurosci; 2018; 12():81. PubMed ID: 29503608
    [No Abstract]   [Full Text] [Related]  

  • 34. Phosphorylation of tau and alpha-synuclein in synaptic-enriched fractions of the frontal cortex in Alzheimer's disease, and in Parkinson's disease and related alpha-synucleinopathies.
    Muntané G; Dalfó E; Martinez A; Ferrer I
    Neuroscience; 2008 Apr; 152(4):913-23. PubMed ID: 18343584
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Substrate Reduction Therapy for Sandhoff Disease through Inhibition of Glucosylceramide Synthase Activity.
    Marshall J; Nietupski JB; Park H; Cao J; Bangari DS; Silvescu C; Wilper T; Randall K; Tietz D; Wang B; Ying X; Leonard JP; Cheng SH
    Mol Ther; 2019 Aug; 27(8):1495-1506. PubMed ID: 31208914
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Clioquinol Improves Cognitive, Motor Function, and Microanatomy of the Alpha-Synuclein hA53T Transgenic Mice.
    Finkelstein DI; Hare DJ; Billings JL; Sedjahtera A; Nurjono M; Arthofer E; George S; Culvenor JG; Bush AI; Adlard PA
    ACS Chem Neurosci; 2016 Jan; 7(1):119-29. PubMed ID: 26481462
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Mutant GBA1 expression and synucleinopathy risk: first insights from cellular and mouse models.
    Sardi SP; Singh P; Cheng SH; Shihabuddin LS; Schlossmacher MG
    Neurodegener Dis; 2012; 10(1-4):195-202. PubMed ID: 22327140
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Resequencing analysis of five Mendelian genes and the top genes from genome-wide association studies in Parkinson's Disease.
    Benitez BA; Davis AA; Jin SC; Ibanez L; Ortega-Cubero S; Pastor P; Choi J; Cooper B; Perlmutter JS; Cruchaga C
    Mol Neurodegener; 2016 Apr; 11():29. PubMed ID: 27094865
    [TBL] [Abstract][Full Text] [Related]  

  • 39. A New Glucocerebrosidase Chaperone Reduces α-Synuclein and Glycolipid Levels in iPSC-Derived Dopaminergic Neurons from Patients with Gaucher Disease and Parkinsonism.
    Aflaki E; Borger DK; Moaven N; Stubblefield BK; Rogers SA; Patnaik S; Schoenen FJ; Westbroek W; Zheng W; Sullivan P; Fujiwara H; Sidhu R; Khaliq ZM; Lopez GJ; Goldstein DS; Ory DS; Marugan J; Sidransky E
    J Neurosci; 2016 Jul; 36(28):7441-52. PubMed ID: 27413154
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Glucocerebrosidase deficits in sporadic Parkinson disease.
    Murphy KE; Halliday GM
    Autophagy; 2014 Jul; 10(7):1350-1. PubMed ID: 24915553
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 20.