BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

94 related articles for article (PubMed ID: 28225275)

  • 1. Synthesis of Novel Synthetic Vitamin K Analogues Prepared by Introduction of a Heteroatom and a Phenyl Group That Induce Highly Selective Neuronal Differentiation of Neuronal Progenitor Cells.
    Kimura K; Hirota Y; Kuwahara S; Takeuchi A; Tode C; Wada A; Osakabe N; Suhara Y
    J Med Chem; 2017 Mar; 60(6):2591-2596. PubMed ID: 28225275
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthetic Small Molecules Derived from Natural Vitamin K Homologues that Induce Selective Neuronal Differentiation of Neuronal Progenitor Cells.
    Suhara Y; Hirota Y; Hanada N; Nishina S; Eguchi S; Sakane R; Nakagawa K; Wada A; Takahashi K; Tokiwa H; Okano T
    J Med Chem; 2015 Sep; 58(17):7088-92. PubMed ID: 26305288
    [TBL] [Abstract][Full Text] [Related]  

  • 3. New Aspects of Vitamin K Research with Synthetic Ligands: Transcriptional Activity via SXR and Neural Differentiation Activity.
    Hirota Y; Suhara Y
    Int J Mol Sci; 2019 Jun; 20(12):. PubMed ID: 31226734
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis of novel vitamin K derivatives with alkylated phenyl groups introduced at the ω-terminal side chain and evaluation of their neural differentiation activities.
    Sakane R; Kimura K; Hirota Y; Ishizawa M; Takagi Y; Wada A; Kuwahara S; Makishima M; Suhara Y
    Bioorg Med Chem Lett; 2017 Nov; 27(21):4881-4884. PubMed ID: 28947152
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis of 2-methyl-1,4-naphthoquinones with higher gamma-glutamyl carboxylase activity than MK-4 both in vitro and in vivo.
    Vermeer C; van 't Hoofd C; Knapen MHJ; Xanthoulea S
    Bioorg Med Chem Lett; 2017 Jan; 27(2):208-211. PubMed ID: 27955810
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure-activity relationships in the conversion of vitamin K analogues into menaquinone-4. Substrates essential to the synthesis of menaquinone-4 in cultured human cell lines.
    Suhara Y; Wada A; Tachibana Y; Watanabe M; Nakamura K; Nakagawa K; Okano T
    Bioorg Med Chem; 2010 May; 18(9):3116-24. PubMed ID: 20378364
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Vitamin K2 modulates proliferation and function of osteoblastic cells in vitro.
    Akedo Y; Hosoi T; Inoue S; Ikegami A; Mizuno Y; Kaneki M; Nakamura T; Ouchi Y; Orimo H
    Biochem Biophys Res Commun; 1992 Sep; 187(2):814-20. PubMed ID: 1530637
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Vitamins K2, K3 and K5 exert in vivo antitumor effects on hepatocellular carcinoma by regulating the expression of G1 phase-related cell cycle molecules.
    Kuriyama S; Hitomi M; Yoshiji H; Nonomura T; Tsujimoto T; Mitoro A; Akahane T; Ogawa M; Nakai S; Deguchi A; Masaki T; Uchida N
    Int J Oncol; 2005 Aug; 27(2):505-11. PubMed ID: 16010434
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis of novel vitamin K2 analogues with modification at the ω-terminal position and their biological evaluation as potent steroid and xenobiotic receptor (SXR) agonists.
    Suhara Y; Watanabe M; Nakagawa K; Wada A; Ito Y; Takeda K; Takahashi K; Okano T
    J Med Chem; 2011 Jun; 54(12):4269-73. PubMed ID: 21561094
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Rapid, high performance method for the determination of vitamin K(1), menaquinone-4 and vitamin K(1) 2,3-epoxide in human serum and plasma using liquid chromatography-hybrid quadrupole linear ion trap mass spectrometry.
    Gentili A; Cafolla A; Gasperi T; Bellante S; Caretti F; Curini R; Fernández VP
    J Chromatogr A; 2014 Apr; 1338():102-10. PubMed ID: 24630057
    [TBL] [Abstract][Full Text] [Related]  

  • 11. [Structure-activity relationship of novel vitamin K analogues as steroid and xenobiotic receptor (SXR) agonists].
    Suhara Y; Motoyoshi S; Hirota Y; Sawada N; Nakagawa K; Tokiwa H; Okano T
    Yakugaku Zasshi; 2012; 132(8):881-6. PubMed ID: 22864345
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery of a novel 2,3,11,11a-tetrahydro-1H-pyrazino[1,2-b]isoquinoline-1,4(6H)-dione series promoting neurogenesis of human neural progenitor cells.
    Lin H; Fang H; Wang J; Meng Q; Dai X; Wu S; Luo J; Pu D; Chen L; Minick D; Arai K; Mandeville ET; Lo E; Holder JC; Chuang TT; Zhao J
    Bioorg Med Chem Lett; 2015 Sep; 25(17):3748-53. PubMed ID: 26142946
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Efficient synthesis and biological evaluation of omega-oxygenated analogues of vitamin K2: study of modification and structure-activity relationship of vitamin K2 metabolites.
    Suhara Y; Murakami A; Kamao M; Mimatsu S; Nakagawa K; Tsugawa N; Okano T
    Bioorg Med Chem Lett; 2007 Mar; 17(6):1622-5. PubMed ID: 17239598
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design and synthesis of biologically active analogues of vitamin K2: evaluation of their biological activities with cultured human cell lines.
    Suhara Y; Hirota Y; Nakagawa K; Kamao M; Tsugawa N; Okano T
    Bioorg Med Chem; 2008 Mar; 16(6):3108-17. PubMed ID: 18171617
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effect of vitamins other than vitamin C on viruses: virus-inactivating activity of vitamin K5.
    Murata A; Sakai S; Oda K; Nakatsumi K; Kato F
    J Nutr Sci Vitaminol (Tokyo); 1983 Dec; 29(6):721-4. PubMed ID: 6676451
    [No Abstract]   [Full Text] [Related]  

  • 16. Hydrogen sulfide promotes proliferation and neuronal differentiation of neural stem cells and protects hypoxia-induced decrease in hippocampal neurogenesis.
    Liu D; Wang Z; Zhan J; Zhang Q; Wang J; Zhang Q; Xian X; Luan Q; Hao A
    Pharmacol Biochem Behav; 2014 Jan; 116():55-63. PubMed ID: 24246910
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ampakine CX546 increases proliferation and neuronal differentiation in subventricular zone stem/progenitor cell cultures.
    Schitine C; Xapelli S; Agasse F; Sardà-Arroyo L; Silva AP; De Melo Reis RA; de Mello FG; Malva JO
    Eur J Neurosci; 2012 Jun; 35(11):1672-83. PubMed ID: 22506985
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Antitumor effects of vitamins K1, K2 and K3 on hepatocellular carcinoma in vitro and in vivo.
    Hitomi M; Yokoyama F; Kita Y; Nonomura T; Masaki T; Yoshiji H; Inoue H; Kinekawa F; Kurokohchi K; Uchida N; Watanabe S; Kuriyama S
    Int J Oncol; 2005 Mar; 26(3):713-20. PubMed ID: 15703828
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Comparative uptake, metabolism, and utilization of menaquinone-4 and phylloquinone in human cultured cell lines.
    Suhara Y; Murakami A; Nakagawa K; Mizuguchi Y; Okano T
    Bioorg Med Chem; 2006 Oct; 14(19):6601-7. PubMed ID: 16798001
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Claulansine F promoted the neuronal differentiation of neural stem and progenitor cells through Akt/GSK-3β/β-catenin pathway.
    Huang JY; Ma YZ; Yuan YH; Zuo W; Chu SF; Liu H; Du GH; Zhang DM; Chen NH
    Eur J Pharmacol; 2016 Sep; 786():72-84. PubMed ID: 27179990
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.