BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1394 related articles for article (PubMed ID: 28230855)

  • 1. Simvastatin-induced cell cycle arrest through inhibition of STAT3/SKP2 axis and activation of AMPK to promote p27 and p21 accumulation in hepatocellular carcinoma cells.
    Wang ST; Ho HJ; Lin JT; Shieh JJ; Wu CY
    Cell Death Dis; 2017 Feb; 8(2):e2626. PubMed ID: 28230855
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Regulation of Akt/FoxO3a/Skp2 Axis Is Critically Involved in Berberine-Induced Cell Cycle Arrest in Hepatocellular Carcinoma Cells.
    Li F; Dong X; Lin P; Jiang J
    Int J Mol Sci; 2018 Jan; 19(2):. PubMed ID: 29360760
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Total alkaloids of Rubus aleaefolius Poir. inhibit the STAT3 signaling pathway leading to suppression of proliferation and cell cycle arrest in a mouse model of hepatocellular carcinoma.
    Zhao J; Lin W; Cao Z; Liu L; Zhuang Q; Zhong X; Hong Z; Peng J
    Oncol Rep; 2013 Sep; 30(3):1309-14. PubMed ID: 23828071
    [TBL] [Abstract][Full Text] [Related]  

  • 4. EB1089 induces Skp2-dependent p27 accumulation, leading to cell growth inhibition and cell cycle G1 phase arrest in human hepatoma cells.
    Luo W; Chen Y; Liu M; Du K; Zheng G; Cai T; Zhang W; Zhao F; Yao T; Yang R; Chen J
    Cancer Invest; 2009 Jan; 27(1):29-37. PubMed ID: 19160095
    [TBL] [Abstract][Full Text] [Related]  

  • 5. STAT3 interacts with Skp2/p27/p21 pathway to regulate the motility and invasion of gastric cancer cells.
    Wei Z; Jiang X; Qiao H; Zhai B; Zhang L; Zhang Q; Wu Y; Jiang H; Sun X
    Cell Signal; 2013 Apr; 25(4):931-8. PubMed ID: 23333463
    [TBL] [Abstract][Full Text] [Related]  

  • 6. BIS targeting induces cellular senescence through the regulation of 14-3-3 zeta/STAT3/SKP2/p27 in glioblastoma cells.
    Lee JJ; Lee JS; Cui MN; Yun HH; Kim HY; Lee SH; Lee JH
    Cell Death Dis; 2014 Nov; 5(11):e1537. PubMed ID: 25412315
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A novel all-trans retinoic acid derivative 4-amino‑2‑trifluoromethyl-phenyl retinate inhibits the proliferation of human hepatocellular carcinoma HepG2 cells by inducing G0/G1 cell cycle arrest and apoptosis via upregulation of p53 and ASPP1 and downregulation of iASPP.
    Liu H; Chen F; Zhang L; Zhou Q; Gui S; Wang Y
    Oncol Rep; 2016 Jul; 36(1):333-41. PubMed ID: 27177208
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hemistepsin A Inhibits Cell Proliferation and Induces G0/G1-Phase Arrest, Cellular Senescence and Apoptosis Via the AMPK and p53/p21 Signals in Human Hepatocellular Carcinoma.
    Baek SY; Hwang UW; Suk HY; Kim YW
    Biomolecules; 2020 May; 10(5):. PubMed ID: 32375410
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Caffeic acid phenethyl ester induced cell cycle arrest and growth inhibition in androgen-independent prostate cancer cells via regulation of Skp2, p53, p21Cip1 and p27Kip1.
    Lin HP; Lin CY; Huo C; Hsiao PH; Su LC; Jiang SS; Chan TM; Chang CH; Chen LT; Kung HJ; Wang HD; Chuu CP
    Oncotarget; 2015 Mar; 6(9):6684-707. PubMed ID: 25788262
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Longikaurin A, a natural ent-kaurane, induces G2/M phase arrest via downregulation of Skp2 and apoptosis induction through ROS/JNK/c-Jun pathway in hepatocellular carcinoma cells.
    Liao YJ; Bai HY; Li ZH; Zou J; Chen JW; Zheng F; Zhang JX; Mai SJ; Zeng MS; Sun HD; Pu JX; Xie D
    Cell Death Dis; 2014 Mar; 5(3):e1137. PubMed ID: 24651440
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Regulation of SIRT1/AMPK axis is critically involved in gallotannin-induced senescence and impaired autophagy leading to cell death in hepatocellular carcinoma cells.
    Kwon HY; Kim JH; Kim B; Srivastava SK; Kim SH
    Arch Toxicol; 2018 Jan; 92(1):241-257. PubMed ID: 28676953
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nobiletin downregulates the SKP2-p21/p27-CDK2 axis to inhibit tumor progression and shows synergistic effects with palbociclib on renal cell carcinoma.
    Chen T; Liu L; Zou Y; Hu X; Zhang W; Zhou T; Luo X; Fu W; Xu J
    Cancer Biol Med; 2021 Feb; 18(1):227-244. PubMed ID: 33628597
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Vorinostat enhances protein stability of p27 and p21 through negative regulation of Skp2 and Cks1 in human breast cancer cells.
    Uehara N; Yoshizawa K; Tsubura A
    Oncol Rep; 2012 Jul; 28(1):105-10. PubMed ID: 22484732
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PCK1 negatively regulates cell cycle progression and hepatoma cell proliferation via the AMPK/p27
    Tuo L; Xiang J; Pan X; Hu J; Tang H; Liang L; Xia J; Hu Y; Zhang W; Huang A; Wang K; Tang N
    J Exp Clin Cancer Res; 2019 Feb; 38(1):50. PubMed ID: 30717766
    [TBL] [Abstract][Full Text] [Related]  

  • 15. All-trans retinoic acid inhibits mesangial cell proliferation by up-regulating p21Waf1/Cip1 and p27Kip1 and down-regulating Skp2.
    Su B; Chen X; Zhong C; Guo N; He J; Fan Y
    J Nephrol; 2012; 25(6):1031-40. PubMed ID: 22344541
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular mechanisms underlying interferon-alpha-induced G0/G1 arrest: CKI-mediated regulation of G1 Cdk-complexes and activation of pocket proteins.
    Sangfelt O; Erickson S; Castro J; Heiden T; Gustafsson A; Einhorn S; Grandér D
    Oncogene; 1999 May; 18(18):2798-810. PubMed ID: 10362250
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Metformin suppresses hepatocellular carcinoma cell growth through induction of cell cycle G1/G0 phase arrest and p21CIP and p27KIP expression and downregulation of cyclin D1 in vitro and in vivo.
    Cai X; Hu X; Cai B; Wang Q; Li Y; Tan X; Hu H; Chen X; Huang J; Cheng J; Jing X
    Oncol Rep; 2013 Nov; 30(5):2449-57. PubMed ID: 24008375
    [TBL] [Abstract][Full Text] [Related]  

  • 18. p27-Associated G1 arrest induced by hinokitiol in human malignant melanoma cells is mediated via down-regulation of pRb, Skp2 ubiquitin ligase, and impairment of Cdk2 function.
    Liu S; Yamauchi H
    Cancer Lett; 2009 Dec; 286(2):240-9. PubMed ID: 19631451
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Interleukin-6 mediates G(0)/G(1) growth arrest in hepatocellular carcinoma through a STAT 3-dependent pathway.
    Moran DM; Mattocks MA; Cahill PA; Koniaris LG; McKillop IH
    J Surg Res; 2008 Jun; 147(1):23-33. PubMed ID: 17574577
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Anticancer activity of dietary xanthone α-mangostin against hepatocellular carcinoma by inhibition of STAT3 signaling via stabilization of SHP1.
    Zhang H; Tan YP; Zhao L; Wang L; Fu NJ; Zheng SP; Shen XF
    Cell Death Dis; 2020 Jan; 11(1):63. PubMed ID: 31980595
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 70.