588 related articles for article (PubMed ID: 28241141)
1. ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia.
Wan L; Wen H; Li Y; Lyu J; Xi Y; Hoshii T; Joseph JK; Wang X; Loh YE; Erb MA; Souza AL; Bradner JE; Shen L; Li W; Li H; Allis CD; Armstrong SA; Shi X
Nature; 2017 Mar; 543(7644):265-269. PubMed ID: 28241141
[TBL] [Abstract][Full Text] [Related]
2. Transcription control by the ENL YEATS domain in acute leukaemia.
Erb MA; Scott TG; Li BE; Xie H; Paulk J; Seo HS; Souza A; Roberts JM; Dastjerdi S; Buckley DL; Sanjana NE; Shalem O; Nabet B; Zeid R; Offei-Addo NK; Dhe-Paganon S; Zhang F; Orkin SH; Winter GE; Bradner JE
Nature; 2017 Mar; 543(7644):270-274. PubMed ID: 28241139
[TBL] [Abstract][Full Text] [Related]
3. Recognition of histone acetylation by the GAS41 YEATS domain promotes H2A.Z deposition in non-small cell lung cancer.
Hsu CC; Shi J; Yuan C; Zhao D; Jiang S; Lyu J; Wang X; Li H; Wen H; Li W; Shi X
Genes Dev; 2018 Jan; 32(1):58-69. PubMed ID: 29437725
[TBL] [Abstract][Full Text] [Related]
4. ENL: structure, function, and roles in hematopoiesis and acute myeloid leukemia.
Zhou J; Ng Y; Chng WJ
Cell Mol Life Sci; 2018 Nov; 75(21):3931-3941. PubMed ID: 30066088
[TBL] [Abstract][Full Text] [Related]
5. Targeting the Epigenetic Reader ENL Inhibits Super-Enhancer-Driven Oncogenic Transcription and Synergizes with BET Inhibition to Suppress Tumor Progression.
Chen Y; Ying Y; Ma W; Ma H; Shi L; Gao X; Jia M; Li M; Song X; Kong W; Chen W; Zheng X; Muluh TA; Wang X; Wang M; Shu XS
Cancer Res; 2024 Apr; 84(8):1237-1251. PubMed ID: 38241700
[TBL] [Abstract][Full Text] [Related]
6. RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia.
Zuber J; Shi J; Wang E; Rappaport AR; Herrmann H; Sison EA; Magoon D; Qi J; Blatt K; Wunderlich M; Taylor MJ; Johns C; Chicas A; Mulloy JC; Kogan SC; Brown P; Valent P; Bradner JE; Lowe SW; Vakoc CR
Nature; 2011 Aug; 478(7370):524-8. PubMed ID: 21814200
[TBL] [Abstract][Full Text] [Related]
7. YEATS2 links histone acetylation to tumorigenesis of non-small cell lung cancer.
Mi W; Guan H; Lyu J; Zhao D; Xi Y; Jiang S; Andrews FH; Wang X; Gagea M; Wen H; Tora L; Dent SYR; Kutateladze TG; Li W; Li H; Shi X
Nat Commun; 2017 Oct; 8(1):1088. PubMed ID: 29057918
[TBL] [Abstract][Full Text] [Related]
8. Discovery of Selective Small-Molecule Inhibitors for the ENL YEATS Domain.
Ma XR; Xu L; Xu S; Klein BJ; Wang H; Das S; Li K; Yang KS; Sohail S; Chapman A; Kutateladze TG; Shi X; Liu WR; Wen H
J Med Chem; 2021 Aug; 64(15):10997-11013. PubMed ID: 34279931
[TBL] [Abstract][Full Text] [Related]
9. Structure-guided development of YEATS domain inhibitors by targeting π-π-π stacking.
Li X; Li XM; Jiang Y; Liu Z; Cui Y; Fung KY; van der Beelen SHE; Tian G; Wan L; Shi X; Allis CD; Li H; Li Y; Li XD
Nat Chem Biol; 2018 Dec; 14(12):1140-1149. PubMed ID: 30374167
[TBL] [Abstract][Full Text] [Related]
10. Discovery of a Selective Inhibitor for the YEATS Domains of ENL/AF9.
Christott T; Bennett J; Coxon C; Monteiro O; Giroud C; Beke V; Felce SL; Gamble V; Gileadi C; Poda G; Al-Awar R; Farnie G; Fedorov O
SLAS Discov; 2019 Feb; 24(2):133-141. PubMed ID: 30359161
[TBL] [Abstract][Full Text] [Related]
11. ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression.
Wen H; Li Y; Xi Y; Jiang S; Stratton S; Peng D; Tanaka K; Ren Y; Xia Z; Wu J; Li B; Barton MC; Li W; Li H; Shi X
Nature; 2014 Apr; 508(7495):263-8. PubMed ID: 24590075
[TBL] [Abstract][Full Text] [Related]
12. Human Polymerase-Associated Factor complex (PAFc) connects the Super Elongation Complex (SEC) to RNA polymerase II on chromatin.
He N; Chan CK; Sobhian B; Chou S; Xue Y; Liu M; Alber T; Benkirane M; Zhou Q
Proc Natl Acad Sci U S A; 2011 Sep; 108(36):E636-45. PubMed ID: 21873227
[TBL] [Abstract][Full Text] [Related]
13. The ENL YEATS epigenetic reader domain critically links MLL-ENL to leukemic stem cell frequency in t(11;19) Leukemia.
Hu H; Saha N; Yang Y; Ahmad E; Lachowski L; Shrestha U; Premkumar V; Ropa J; Chen L; Teahan B; Grigsby S; Marschalek R; Nikolovska-Coleska Z; Muntean AG
Leukemia; 2023 Jan; 37(1):190-201. PubMed ID: 36435883
[TBL] [Abstract][Full Text] [Related]
14. Small-Molecule Inhibition of the Acyl-Lysine Reader ENL as a Strategy against Acute Myeloid Leukemia.
Liu Y; Li Q; Alikarami F; Barrett DR; Mahdavi L; Li H; Tang S; Khan TA; Michino M; Hill C; Song L; Yang L; Li Y; Pokharel SP; Stamford AW; Liverton N; Renzetti LM; Taylor S; Watt GF; Ladduwahetty T; Kargman S; Meinke PT; Foley MA; Shi J; Li H; Carroll M; Chen CW; Gardini A; Maillard I; Huggins DJ; Bernt KM; Wan L
Cancer Discov; 2022 Nov; 12(11):2684-2709. PubMed ID: 36053276
[TBL] [Abstract][Full Text] [Related]
15. The YEATS domain epigenetic reader proteins ENL and AF9 and their therapeutic value in leukemia.
Hu H; Muntean AG
Exp Hematol; 2023 Aug; 124():15-21. PubMed ID: 37295550
[TBL] [Abstract][Full Text] [Related]
16. Small-molecule inhibitor of AF9/ENL-DOT1L/AF4/AFF4 interactions suppresses malignant gene expression and tumor growth.
Wu F; Nie S; Yao Y; Huo T; Li X; Wu X; Zhao J; Lin YL; Zhang Y; Mo Q; Song Y
Theranostics; 2021; 11(17):8172-8184. PubMed ID: 34373735
[TBL] [Abstract][Full Text] [Related]
17. Fragment-Based Discovery of AF9 YEATS Domain Inhibitors.
Liu Y; Jin R; Lu H; Bian K; Wang R; Wang L; Gao R; Zhang J; Wu J; Yao X; Liu X; Liu D; Wang X; Zhang Z; Ruan K
Int J Mol Sci; 2022 Mar; 23(7):. PubMed ID: 35409252
[TBL] [Abstract][Full Text] [Related]
18. Acetylation on histone H3 lysine 9 mediates a switch from transcription initiation to elongation.
Gates LA; Shi J; Rohira AD; Feng Q; Zhu B; Bedford MT; Sagum CA; Jung SY; Qin J; Tsai MJ; Tsai SY; Li W; Foulds CE; O'Malley BW
J Biol Chem; 2017 Sep; 292(35):14456-14472. PubMed ID: 28717009
[TBL] [Abstract][Full Text] [Related]
19. Conformational and Thermodynamic Differences Underlying Wild-Type and Mutant Eleven-Nineteen-Leukemia YEATS Domain Specificity for Epigenetic Marks.
Baweja L; Wereszczynski J
J Chem Inf Model; 2023 Feb; 63(4):1229-1238. PubMed ID: 36786550
[TBL] [Abstract][Full Text] [Related]
20. Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia.
Dawson MA; Prinjha RK; Dittmann A; Giotopoulos G; Bantscheff M; Chan WI; Robson SC; Chung CW; Hopf C; Savitski MM; Huthmacher C; Gudgin E; Lugo D; Beinke S; Chapman TD; Roberts EJ; Soden PE; Auger KR; Mirguet O; Doehner K; Delwel R; Burnett AK; Jeffrey P; Drewes G; Lee K; Huntly BJ; Kouzarides T
Nature; 2011 Oct; 478(7370):529-33. PubMed ID: 21964340
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
