164 related articles for article (PubMed ID: 28253432)
1. Spectroscopic and Computational Investigations of Ligand Binding to IspH: Discovery of Non-diphosphate Inhibitors.
O'Dowd B; Williams S; Wang H; No JH; Rao G; Wang W; McCammon JA; Cramer SP; Oldfield E
Chembiochem; 2017 May; 18(10):914-920. PubMed ID: 28253432
[TBL] [Abstract][Full Text] [Related]
2. Two unexpected promiscuous activities of the iron-sulfur protein IspH in production of isoprene and isoamylene.
Ge D; Xue Y; Ma Y
Microb Cell Fact; 2016 May; 15():79. PubMed ID: 27169371
[TBL] [Abstract][Full Text] [Related]
3. The Active-Site [4Fe-4S] Cluster in the Isoprenoid Biosynthesis Enzyme IspH Adopts Unexpected Redox States during Ligand Binding and Catalysis.
Ghebreamlak S; Stoian SA; Lees NS; Cronin B; Smith F; Ross MO; Telser J; Hoffman BM; Duin EC
J Am Chem Soc; 2024 Feb; 146(6):3926-3942. PubMed ID: 38291562
[TBL] [Abstract][Full Text] [Related]
4. Bioorganometallic mechanism of action, and inhibition, of IspH.
Wang W; Wang K; Liu YL; No JH; Li J; Nilges MJ; Oldfield E
Proc Natl Acad Sci U S A; 2010 Mar; 107(10):4522-7. PubMed ID: 20173096
[TBL] [Abstract][Full Text] [Related]
5. A closer look at the spectroscopic properties of possible reaction intermediates in wild-type and mutant (E)-4-hydroxy-3-methylbut-2-enyl diphosphate reductase.
Xu W; Lees NS; Hall D; Welideniya D; Hoffman BM; Duin EC
Biochemistry; 2012 Jun; 51(24):4835-49. PubMed ID: 22646150
[TBL] [Abstract][Full Text] [Related]
6. Exceptionally high percentage of IPP synthesis by Ginkgo biloba IspH is mainly due to Phe residue in the active site.
Shin BK; Kim M; Han J
Phytochemistry; 2017 Apr; 136():9-14. PubMed ID: 28139297
[TBL] [Abstract][Full Text] [Related]
7. Isoprenoid biosynthesis via the methylerythritol phosphate pathway: the (E)-4-hydroxy-3-methylbut-2-enyl diphosphate reductase (LytB/IspH) from Escherichia coli is a [4Fe-4S] protein.
Wolff M; Seemann M; Tse Sum Bui B; Frapart Y; Tritsch D; Garcia Estrabot A; Rodríguez-Concepción M; Boronat A; Marquet A; Rohmer M
FEBS Lett; 2003 Apr; 541(1-3):115-20. PubMed ID: 12706830
[TBL] [Abstract][Full Text] [Related]
8. Insights into the binding of pyridines to the iron-sulfur enzyme IspH.
Span I; Wang K; Eisenreich W; Bacher A; Zhang Y; Oldfield E; Groll M
J Am Chem Soc; 2014 Jun; 136(22):7926-32. PubMed ID: 24813236
[TBL] [Abstract][Full Text] [Related]
9. Inhibition of the 4Fe-4S Proteins IspG and IspH: an EPR, ENDOR and HYSCORE Investigation.
Guerra F; Wang K; Li J; Wang W; Liu YL; Amin S; Oldfield E
Chem Sci; 2014 Apr; 5(4):1642-1649. PubMed ID: 24999381
[TBL] [Abstract][Full Text] [Related]
10. Broken-Symmetry DFT Computations for the Reaction Pathway of IspH, an Iron-Sulfur Enzyme in Pathogenic Bacteria.
Blachly PG; Sandala GM; Giammona DA; Bashford D; McCammon JA; Noodleman L
Inorg Chem; 2015 Jul; 54(13):6439-61. PubMed ID: 26098647
[TBL] [Abstract][Full Text] [Related]
11. Crystal structures of mutant IspH proteins reveal a rotation of the substrate's hydroxymethyl group during catalysis.
Span I; Gräwert T; Bacher A; Eisenreich W; Groll M
J Mol Biol; 2012 Feb; 416(1):1-9. PubMed ID: 22137895
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of the Fe(4)S(4)-cluster-containing protein IspH (LytB): electron paramagnetic resonance, metallacycles, and mechanisms.
Wang K; Wang W; No JH; Zhang Y; Zhang Y; Oldfield E
J Am Chem Soc; 2010 May; 132(19):6719-27. PubMed ID: 20426416
[TBL] [Abstract][Full Text] [Related]
13. Discovery of acetylene hydratase activity of the iron-sulphur protein IspH.
Span I; Wang K; Wang W; Zhang Y; Bacher A; Eisenreich W; Li K; Schulz C; Oldfield E; Groll M
Nat Commun; 2012; 3():1042. PubMed ID: 22948824
[TBL] [Abstract][Full Text] [Related]
14. IspH protein of Escherichia coli: studies on iron-sulfur cluster implementation and catalysis.
Gräwert T; Kaiser J; Zepeck F; Laupitz R; Hecht S; Amslinger S; Schramek N; Schleicher E; Weber S; Haslbeck M; Buchner J; Rieder C; Arigoni D; Bacher A; Eisenreich W; Rohdich F
J Am Chem Soc; 2004 Oct; 126(40):12847-55. PubMed ID: 15469281
[TBL] [Abstract][Full Text] [Related]
15. Structure and Function of Four Classes of the 4Fe-4S Protein, IspH.
Rao G; Oldfield E
Biochemistry; 2016 Jul; 55(29):4119-29. PubMed ID: 27357244
[TBL] [Abstract][Full Text] [Related]
16. Targeting isoprenoid biosynthesis for drug discovery: bench to bedside.
Oldfield E
Acc Chem Res; 2010 Sep; 43(9):1216-26. PubMed ID: 20560544
[TBL] [Abstract][Full Text] [Related]
17. Organometallic mechanism of action and inhibition of the 4Fe-4S isoprenoid biosynthesis protein GcpE (IspG).
Wang W; Li J; Wang K; Huang C; Zhang Y; Oldfield E
Proc Natl Acad Sci U S A; 2010 Jun; 107(25):11189-93. PubMed ID: 20534554
[TBL] [Abstract][Full Text] [Related]
18. Pyridine inhibitor binding to the 4Fe-4S protein A. aeolicus IspH (LytB): a HYSCORE Investigation.
Wang W; Li J; Wang K; Smirnova TI; Oldfield E
J Am Chem Soc; 2011 May; 133(17):6525-8. PubMed ID: 21486034
[TBL] [Abstract][Full Text] [Related]
19. Inhibition of IspH, a [4Fe-4S]2+ enzyme involved in the biosynthesis of isoprenoids via the methylerythritol phosphate pathway.
Janthawornpong K; Krasutsky S; Chaignon P; Rohmer M; Poulter CD; Seemann M
J Am Chem Soc; 2013 Feb; 135(5):1816-22. PubMed ID: 23316732
[TBL] [Abstract][Full Text] [Related]
20. Methylerythritol Phosphate Pathway: Enzymatic Evidence for a Rotation in the LytB/IspH-Catalyzed Reaction.
Chaignon P; Petit BE; Vincent B; Allouche L; Seemann M
Chemistry; 2020 Jan; 26(5):1032-1036. PubMed ID: 31756006
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
