128 related articles for article (PubMed ID: 28253972)
1. In Vitro Characterization of VPS34 Lipid Kinase Inhibition by Small Molecules.
Fassy F; Dureuil C; Lamberton A; Mathieu M; Michot N; Ronan B; Pasquier B
Methods Enzymol; 2017; 587():447-464. PubMed ID: 28253972
[TBL] [Abstract][Full Text] [Related]
2. A highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagy.
Ronan B; Flamand O; Vescovi L; Dureuil C; Durand L; Fassy F; Bachelot MF; Lamberton A; Mathieu M; Bertrand T; Marquette JP; El-Ahmad Y; Filoche-Romme B; Schio L; Garcia-Echeverria C; Goulaouic H; Pasquier B
Nat Chem Biol; 2014 Dec; 10(12):1013-9. PubMed ID: 25326666
[TBL] [Abstract][Full Text] [Related]
3. Discovery of (2S)-8-[(3R)-3-methylmorpholin-4-yl]-1-(3-methyl-2-oxobutyl)-2-(trifluoromethyl)-3,4-dihydro-2H-pyrimido[1,2-a]pyrimidin-6-one: a novel potent and selective inhibitor of Vps34 for the treatment of solid tumors.
Pasquier B; El-Ahmad Y; Filoche-Rommé B; Dureuil C; Fassy F; Abecassis PY; Mathieu M; Bertrand T; Benard T; Barrière C; El Batti S; Letallec JP; Sonnefraud V; Brollo M; Delbarre L; Loyau V; Pilorge F; Bertin L; Richepin P; Arigon J; Labrosse JR; Clément J; Durand F; Combet R; Perraut P; Leroy V; Gay F; Lefrançois D; Bretin F; Marquette JP; Michot N; Caron A; Castell C; Schio L; McCort G; Goulaouic H; Garcia-Echeverria C; Ronan B
J Med Chem; 2015 Jan; 58(1):376-400. PubMed ID: 25402320
[TBL] [Abstract][Full Text] [Related]
4. Development of in vitro PIK3C3/VPS34 complex protein assay for autophagy-specific inhibitor screening.
Kim TM; Baek JH; Kim JH; Oh MS; Kim J
Anal Biochem; 2015 Jul; 480():21-7. PubMed ID: 25862085
[TBL] [Abstract][Full Text] [Related]
5. SAR405, a PIK3C3/Vps34 inhibitor that prevents autophagy and synergizes with MTOR inhibition in tumor cells.
Pasquier B
Autophagy; 2015 Apr; 11(4):725-6. PubMed ID: 25905679
[TBL] [Abstract][Full Text] [Related]
6. The intricate regulation and complex functions of the Class III phosphoinositide 3-kinase Vps34.
Backer JM
Biochem J; 2016 Aug; 473(15):2251-71. PubMed ID: 27470591
[TBL] [Abstract][Full Text] [Related]
7. Class III phosphoinositide 3-kinase/VPS34 and dynamin are critical for apical endocytic recycling.
Carpentier S; N'Kuli F; Grieco G; Van Der Smissen P; Janssens V; Emonard H; Bilanges B; Vanhaesebroeck B; Gaide Chevronnay HP; Pierreux CE; Tyteca D; Courtoy PJ
Traffic; 2013 Aug; 14(8):933-48. PubMed ID: 23621784
[TBL] [Abstract][Full Text] [Related]
8. VPS34 complexes from a structural perspective.
Ohashi Y; Tremel S; Williams RL
J Lipid Res; 2019 Feb; 60(2):229-241. PubMed ID: 30397185
[TBL] [Abstract][Full Text] [Related]
9. Cinderella finds her shoe: the first Vps34 inhibitor uncovers a new PI3K-AGC protein kinase connection.
Bilanges B; Vanhaesebroeck B
Biochem J; 2014 Dec; 464(2):e7-10. PubMed ID: 25395352
[TBL] [Abstract][Full Text] [Related]
10. Selective autophagy inhibition through disruption of the PIK3C3-containing complex I.
Pavlinov I; Salkovski M; Aldrich LN
Autophagy; 2020 Aug; 16(8):1547-1549. PubMed ID: 32619130
[TBL] [Abstract][Full Text] [Related]
11. VPS34 Acetylation Controls Its Lipid Kinase Activity and the Initiation of Canonical and Non-canonical Autophagy.
Su H; Yang F; Wang Q; Shen Q; Huang J; Peng C; Zhang Y; Wan W; Wong CCL; Sun Q; Wang F; Zhou T; Liu W
Mol Cell; 2017 Sep; 67(6):907-921.e7. PubMed ID: 28844862
[TBL] [Abstract][Full Text] [Related]
12. Vps34 Kinase Domain Dynamics Regulate the Autophagic PI 3-Kinase Complex.
Stjepanovic G; Baskaran S; Lin MG; Hurley JH
Mol Cell; 2017 Aug; 67(3):528-534.e3. PubMed ID: 28757208
[TBL] [Abstract][Full Text] [Related]
13. The Role of Phosphatidylinositol 3-Kinase Catalytic Subunit Type 3 in the Pathogenesis of Human Cancer.
Chu CA; Wang YW; Chen YL; Chen HW; Chuang JJ; Chang HY; Ho CL; Chang C; Chow NH; Lee CT
Int J Mol Sci; 2021 Oct; 22(20):. PubMed ID: 34681622
[TBL] [Abstract][Full Text] [Related]
14. Bacterial Overexpression and Denaturing Purification of VPS34-Binding Domain of Beclin 1.
Baek JH; Jung J; Seo J; Kim JH; Kim J
J Microbiol Biotechnol; 2016 Oct; 26(10):1808-1816. PubMed ID: 27363473
[TBL] [Abstract][Full Text] [Related]
15. Beclin 1-ATG14L Protein-Protein Interaction Inhibitor Selectively Inhibits Autophagy through Disruption of VPS34 Complex I.
Pavlinov I; Salkovski M; Aldrich LN
J Am Chem Soc; 2020 May; 142(18):8174-8182. PubMed ID: 32320221
[TBL] [Abstract][Full Text] [Related]
16. Regulation of mammalian autophagy by class II and III PI 3-kinases through PI3P synthesis.
Devereaux K; Dall'Armi C; Alcazar-Roman A; Ogasawara Y; Zhou X; Wang F; Yamamoto A; De Camilli P; Di Paolo G
PLoS One; 2013; 8(10):e76405. PubMed ID: 24098492
[TBL] [Abstract][Full Text] [Related]
17. The class III phosphatidylinositol 3-kinase Vps34 in Saccharomyces cerevisiae.
Reidick C; Boutouja F; Platta HW
Biol Chem; 2017 May; 398(5-6):677-685. PubMed ID: 27935849
[TBL] [Abstract][Full Text] [Related]
18. Simultaneous inhibition of Vps34 kinase would enhance PI3Kδ inhibitor cytotoxicity in the B-cell malignancies.
Liu X; Wang A; Liang X; Liu J; Zou F; Chen C; Zhao Z; Deng Y; Wu H; Qi Z; Wang B; Wang L; Liu F; Xu Y; Wang W; Fernandes SM; Stone RM; Galinsky IA; Brown JR; Loh T; Griffin JD; Zhang S; Weisberg EL; Zhang X; Liu J; Liu Q
Oncotarget; 2016 Aug; 7(33):53515-53525. PubMed ID: 27447747
[TBL] [Abstract][Full Text] [Related]
19. FBXL20-mediated Vps34 ubiquitination as a p53 controlled checkpoint in regulating autophagy and receptor degradation.
Xiao J; Zhang T; Xu D; Wang H; Cai Y; Jin T; Liu M; Jin M; Wu K; Yuan J
Genes Dev; 2015 Jan; 29(2):184-96. PubMed ID: 25593308
[TBL] [Abstract][Full Text] [Related]
20. Targeting the Autophagy Specific Lipid Kinase VPS34 for Cancer Treatment: An Integrative Repurposing Strategy.
Murali P; Verma K; Rungrotmongkol T; Thangavelu P; Karuppasamy R
Protein J; 2021 Feb; 40(1):41-53. PubMed ID: 33400087
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
