181 related articles for article (PubMed ID: 28254379)
1. New natural amino acid-bearing prodrugs boost pterostilbene's oral pharmacokinetic and distribution profile.
Azzolini M; Mattarei A; La Spina M; Fanin M; Chiodarelli G; Romio M; Zoratti M; Paradisi C; Biasutto L
Eur J Pharm Biopharm; 2017 Jun; 115():149-158. PubMed ID: 28254379
[TBL] [Abstract][Full Text] [Related]
2. Intestinal absorption and activation of decitabine amino acid ester prodrugs mediated by peptide transporter PEPT1 and enterocyte enzymes.
Tao W; Zhao D; Sun M; Wang Z; Lin B; Bao Y; Li Y; He Z; Sun Y; Sun J
Int J Pharm; 2018 Apr; 541(1-2):64-71. PubMed ID: 29471144
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and Evaluation as Prodrugs of Hydrophilic Carbamate Ester Analogues of Resveratrol.
Azzolini M; Mattarei A; La Spina M; Marotta E; Zoratti M; Paradisi C; Biasutto L
Mol Pharm; 2015 Sep; 12(9):3441-54. PubMed ID: 26252229
[TBL] [Abstract][Full Text] [Related]
4. Amino Acid Carbamates As Prodrugs Of Resveratrol.
Mattarei A; Azzolini M; La Spina M; Zoratti M; Paradisi C; Biasutto L
Sci Rep; 2015 Oct; 5():15216. PubMed ID: 26463125
[TBL] [Abstract][Full Text] [Related]
5. Bifunctional peptidomimetic prodrugs of didanosine for improved intestinal permeability and enhanced acidic stability: synthesis, transepithelial transport, chemical stability and pharmacokinetics.
Yan Z; Sun J; Chang Y; Liu Y; Fu Q; Xu Y; Sun Y; Pu X; Zhang Y; Jing Y; Yin S; Zhu M; Wang Y; He Z
Mol Pharm; 2011 Apr; 8(2):319-29. PubMed ID: 21280612
[TBL] [Abstract][Full Text] [Related]
6. Pharmacokinetics of amino acid ester prodrugs of acyclovir after oral administration: interaction with the transporters on Caco-2 cells.
Katragadda S; Jain R; Kwatra D; Hariharan S; Mitra AK
Int J Pharm; 2008 Oct; 362(1-2):93-101. PubMed ID: 18638532
[TBL] [Abstract][Full Text] [Related]
7. Increasing oral absorption of polar neuraminidase inhibitors: a prodrug transporter approach applied to oseltamivir analogue.
Gupta D; Varghese Gupta S; Dahan A; Tsume Y; Hilfinger J; Lee KD; Amidon GL
Mol Pharm; 2013 Feb; 10(2):512-22. PubMed ID: 23244438
[TBL] [Abstract][Full Text] [Related]
8. Enhancing Oral Bioavailability of Cyclic RGD Hexa-peptides by the Lipophilic Prodrug Charge Masking Approach: Redirection of Peptide Intestinal Permeability from a Paracellular to Transcellular Pathway.
Schumacher-Klinger A; Fanous J; Merzbach S; Weinmüller M; Reichart F; Räder AFB; Gitlin-Domagalska A; Gilon C; Kessler H; Hoffman A
Mol Pharm; 2018 Aug; 15(8):3468-3477. PubMed ID: 29976060
[TBL] [Abstract][Full Text] [Related]
9. Synthesis, transport and pharmacokinetics of 5'-amino acid ester prodrugs of 1-beta-D-arabinofuranosylcytosine.
Sun Y; Sun J; Shi S; Jing Y; Yin S; Chen Y; Li G; Xu Y; He Z
Mol Pharm; 2009; 6(1):315-25. PubMed ID: 19115956
[TBL] [Abstract][Full Text] [Related]
10. Transport of levovirin prodrugs in the human intestinal Caco-2 cell line.
Li F; Hong L; Mau CI; Chan R; Hendricks T; Dvorak C; Yee C; Harris J; Alfredson T
J Pharm Sci; 2006 Jun; 95(6):1318-25. PubMed ID: 16634069
[TBL] [Abstract][Full Text] [Related]
11. Ethylene glycol-linked amino acid diester prodrugs of oleanolic acid for PepT1-mediated transport: synthesis, intestinal permeability and pharmacokinetics.
Cao F; Jia J; Yin Z; Gao Y; Sha L; Lai Y; Ping Q; Zhang Y
Mol Pharm; 2012 Aug; 9(8):2127-35. PubMed ID: 22352697
[TBL] [Abstract][Full Text] [Related]
12. N-Monosubstituted Methoxy-oligo(ethylene glycol) Carbamate Ester Prodrugs of Resveratrol.
Mattarei A; Azzolini M; Zoratti M; Biasutto L; Paradisi C
Molecules; 2015 Sep; 20(9):16085-102. PubMed ID: 26404221
[TBL] [Abstract][Full Text] [Related]
13. Propylene glycol-linked amino acid/dipeptide diester prodrugs of oleanolic acid for PepT1-mediated transport: synthesis, intestinal permeability, and pharmacokinetics.
Cao F; Gao Y; Wang M; Fang L; Ping Q
Mol Pharm; 2013 Apr; 10(4):1378-87. PubMed ID: 23339520
[TBL] [Abstract][Full Text] [Related]
14. Pharmacokinetic studies of naproxen amides of some amino acid esters with promising colorectal cancer chemopreventive activity.
Aboul-Fadl T; Al-Hamad SS; Fouad EA
Bioorg Chem; 2018 Feb; 76():370-379. PubMed ID: 29241109
[TBL] [Abstract][Full Text] [Related]
15. New water-soluble carbamate ester derivatives of resveratrol.
Mattarei A; Carraro M; Azzolini M; Paradisi C; Zoratti M; Biasutto L
Molecules; 2014 Oct; 19(10):15900-17. PubMed ID: 25275336
[TBL] [Abstract][Full Text] [Related]
16. Floxuridine amino acid ester prodrugs: enhancing Caco-2 permeability and resistance to glycosidic bond metabolism.
Landowski CP; Song X; Lorenzi PL; Hilfinger JM; Amidon GL
Pharm Res; 2005 Sep; 22(9):1510-8. PubMed ID: 16132363
[TBL] [Abstract][Full Text] [Related]
17. In vitro and in vivo evaluations of the metabolism, pharmacokinetics, and bioavailability of ester prodrugs of L-767,679, a potent fibrinogen receptor antagonist: an approach for the selection of a prodrug candidate.
Prueksaritanont T; Gorham LM; Breslin MJ; Hutchinson JH; Hartman GD; Vyas KP; Baillie TA
Drug Metab Dispos; 1997 Aug; 25(8):978-84. PubMed ID: 9280406
[TBL] [Abstract][Full Text] [Related]
18. Cationic Ester Prodrugs of Curcumin with N,N-dimethyl Amino Acid Promoieties Improved Poor Water Solubility and Intestinal Absorption.
Hirano-Kusuda M; Setoguchi S; Koga M; Goto S; Yamada A; Watase D; Nagata-Akaho N; Karube Y; Matsunaga K; Takata J
Pharm Res; 2023 May; 40(5):1299-1310. PubMed ID: 37081301
[TBL] [Abstract][Full Text] [Related]
19. A study of the intestinal absorption of an ester-type prodrug, ME3229, in rats: active efflux transport as a cause of poor bioavailability of the active drug.
Okudaira N; Tatebayashi T; Speirs GC; Komiya I; Sugiyama Y
J Pharmacol Exp Ther; 2000 Aug; 294(2):580-7. PubMed ID: 10900235
[TBL] [Abstract][Full Text] [Related]
20. Design, Synthesis, and Pharmacokinetic Evaluation of Phosphate and Amino Acid Ester Prodrugs for Improving the Oral Bioavailability of the HIV-1 Protease Inhibitor Atazanavir.
A M Subbaiah M; Mandlekar S; Desikan S; Ramar T; Subramani L; Annadurai M; Desai SD; Sinha S; Jenkins SM; Krystal MR; Subramanian M; Sridhar S; Padmanabhan S; Bhutani P; Arla R; Singh S; Sinha J; Thakur M; Kadow JF; Meanwell NA
J Med Chem; 2019 Apr; 62(7):3553-3574. PubMed ID: 30938524
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
