212 related articles for article (PubMed ID: 28263461)
1. Current Concepts in Methadone Metabolism and Transport.
Kharasch ED
Clin Pharmacol Drug Dev; 2017 Mar; 6(2):125-134. PubMed ID: 28263461
[TBL] [Abstract][Full Text] [Related]
2. Role of hepatic and intestinal cytochrome P450 3A and 2B6 in the metabolism, disposition, and miotic effects of methadone.
Kharasch ED; Hoffer C; Whittington D; Sheffels P
Clin Pharmacol Ther; 2004 Sep; 76(3):250-69. PubMed ID: 15371986
[TBL] [Abstract][Full Text] [Related]
3. Methadone Pharmacogenetics: CYP2B6 Polymorphisms Determine Plasma Concentrations, Clearance, and Metabolism.
Kharasch ED; Regina KJ; Blood J; Friedel C
Anesthesiology; 2015 Nov; 123(5):1142-53. PubMed ID: 26389554
[TBL] [Abstract][Full Text] [Related]
4. Influence of HIV antiretrovirals on methadone N-demethylation and transport.
Campbell SD; Gadel S; Friedel C; Crafford A; Regina KJ; Kharasch ED
Biochem Pharmacol; 2015 May; 95(2):115-25. PubMed ID: 25801005
[TBL] [Abstract][Full Text] [Related]
5. Enantiomeric metabolic interactions and stereoselective human methadone metabolism.
Totah RA; Allen KE; Sheffels P; Whittington D; Kharasch ED
J Pharmacol Exp Ther; 2007 Apr; 321(1):389-99. PubMed ID: 17259447
[TBL] [Abstract][Full Text] [Related]
6. Stereoselective metabolism of methadone N-demethylation by cytochrome P4502B6 and 2C19.
Gerber JG; Rhodes RJ; Gal J
Chirality; 2004 Jan; 16(1):36-44. PubMed ID: 14628297
[TBL] [Abstract][Full Text] [Related]
7. Differences in Methadone Metabolism by CYP2B6 Variants.
Gadel S; Friedel C; Kharasch ED
Drug Metab Dispos; 2015 Jul; 43(7):994-1001. PubMed ID: 25897175
[TBL] [Abstract][Full Text] [Related]
8. Mechanism of efavirenz influence on methadone pharmacokinetics and pharmacodynamics.
Kharasch ED; Whittington D; Ensign D; Hoffer C; Bedynek PS; Campbell S; Stubbert K; Crafford A; London A; Kim T
Clin Pharmacol Ther; 2012 Apr; 91(4):673-84. PubMed ID: 22398970
[TBL] [Abstract][Full Text] [Related]
9. Role of cytochrome P4502B6 in methadone metabolism and clearance.
Kharasch ED; Stubbert K
J Clin Pharmacol; 2013 Mar; 53(3):305-13. PubMed ID: 23361846
[TBL] [Abstract][Full Text] [Related]
10. Drug-Drug Interaction Studies of Methadone and Antiviral Drugs: Lessons Learned.
Younis IR; Lakota EA; Volpe DA; Patel V; Xu Y; Sahajwalla CG
J Clin Pharmacol; 2019 Aug; 59(8):1035-1043. PubMed ID: 30973652
[TBL] [Abstract][Full Text] [Related]
11. Metabolomics of methadone: clinical and forensic toxicological implications and variability of dose response.
Dinis-Oliveira RJ
Drug Metab Rev; 2016 Nov; 48(4):568-576. PubMed ID: 27320437
[TBL] [Abstract][Full Text] [Related]
12. Methadone enantiomer plasma levels, CYP2B6, CYP2C19, and CYP2C9 genotypes, and response to treatment.
Crettol S; Déglon JJ; Besson J; Croquette-Krokkar M; Gothuey I; Hämmig R; Monnat M; Hüttemann H; Baumann P; Eap CB
Clin Pharmacol Ther; 2005 Dec; 78(6):593-604. PubMed ID: 16338275
[TBL] [Abstract][Full Text] [Related]
13. CYP2B6 SNPs are associated with methadone dose required for effective treatment of opioid addiction.
Levran O; Peles E; Hamon S; Randesi M; Adelson M; Kreek MJ
Addict Biol; 2013 Jul; 18(4):709-16. PubMed ID: 21790905
[TBL] [Abstract][Full Text] [Related]
14. Methadone metabolism and clearance are induced by nelfinavir despite inhibition of cytochrome P4503A (CYP3A) activity.
Kharasch ED; Walker A; Whittington D; Hoffer C; Bedynek PS
Drug Alcohol Depend; 2009 May; 101(3):158-68. PubMed ID: 19232844
[TBL] [Abstract][Full Text] [Related]
15. Impact of ABCB1 and CYP2B6 genetic polymorphisms on methadone metabolism, dose and treatment response in patients with opioid addiction: a systematic review and meta-analysis.
Dennis BB; Bawor M; Thabane L; Sohani Z; Samaan Z
PLoS One; 2014; 9(1):e86114. PubMed ID: 24489693
[TBL] [Abstract][Full Text] [Related]
16. Methadone N-demethylation by the common CYP2B6 allelic variant CYP2B6.6.
Gadel S; Crafford A; Regina K; Kharasch ED
Drug Metab Dispos; 2013 Apr; 41(4):709-13. PubMed ID: 23298862
[TBL] [Abstract][Full Text] [Related]
17. ABCB1, CYP2B6, and CYP3A4 genetic polymorphisms do not affect methadone maintenance treatment in HCV-positive patients.
Sutlović D; Ključević Ž; Kuret S
Arh Hig Rada Toksikol; 2020 Dec; 71(4):353-358. PubMed ID: 33410778
[TBL] [Abstract][Full Text] [Related]
18. Pharmacokinetic modeling of R and S-Methadone and their metabolites to study the effects of various covariates in post-operative children.
Aruldhas BW; Quinney SK; Overholser BR; Heathman MA; Masters AR; Ly RC; Gao H; Packiasabapathy S; Sadhasivam S
CPT Pharmacometrics Syst Pharmacol; 2021 Oct; 10(10):1183-1194. PubMed ID: 34435753
[TBL] [Abstract][Full Text] [Related]
19. Role of CYP2B6 in stereoselective human methadone metabolism.
Totah RA; Sheffels P; Roberts T; Whittington D; Thummel K; Kharasch ED
Anesthesiology; 2008 Mar; 108(3):363-74. PubMed ID: 18292673
[TBL] [Abstract][Full Text] [Related]
20. Relationship between CYP2B6*6 and cold pressor pain sensitivity in opioid dependent patients on methadone maintenance therapy (MMT).
Zahari Z; Lee CS; Ibrahim MA; Musa N; Mohd Yasin MA; Lee YY; Tan SC; Mohamad N; Ismail R
Drug Alcohol Depend; 2016 Aug; 165():143-50. PubMed ID: 27289271
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]