BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

542 related articles for article (PubMed ID: 28265061)

  • 1. Amyotrophic lateral sclerosis-linked mutations increase the viscosity of liquid-like TDP-43 RNP granules in neurons.
    Gopal PP; Nirschl JJ; Klinman E; Holzbaur EL
    Proc Natl Acad Sci U S A; 2017 Mar; 114(12):E2466-E2475. PubMed ID: 28265061
    [TBL] [Abstract][Full Text] [Related]  

  • 2. ALS-linked mutations enlarge TDP-43-enriched neuronal RNA granules in the dendritic arbor.
    Liu-Yesucevitz L; Lin AY; Ebata A; Boon JY; Reid W; Xu YF; Kobrin K; Murphy GJ; Petrucelli L; Wolozin B
    J Neurosci; 2014 Mar; 34(12):4167-74. PubMed ID: 24647938
    [TBL] [Abstract][Full Text] [Related]  

  • 3. RNP granules in ALS and neurodegeneration: From multifunctional membraneless organelles to therapeutic opportunities.
    Shelkovnikova TA; Hautbergue GM
    Int Rev Neurobiol; 2024; 176():455-479. PubMed ID: 38802180
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Altered mRNP granule dynamics in FTLD pathogenesis.
    Bowden HA; Dormann D
    J Neurochem; 2016 Aug; 138 Suppl 1():112-33. PubMed ID: 26938019
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity.
    Daigle JG; Krishnamurthy K; Ramesh N; Casci I; Monaghan J; McAvoy K; Godfrey EW; Daniel DC; Johnson EM; Monahan Z; Shewmaker F; Pasinelli P; Pandey UB
    Acta Neuropathol; 2016 Apr; 131(4):605-20. PubMed ID: 26728149
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tar DNA binding protein of 43 kDa (TDP-43), 14-3-3 proteins and copper/zinc superoxide dismutase (SOD1) interact to modulate NFL mRNA stability. Implications for altered RNA processing in amyotrophic lateral sclerosis (ALS).
    Volkening K; Leystra-Lantz C; Yang W; Jaffee H; Strong MJ
    Brain Res; 2009 Dec; 1305():168-82. PubMed ID: 19815002
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Motor neurons and glia exhibit specific individualized responses to TDP-43 expression in a Drosophila model of amyotrophic lateral sclerosis.
    Estes PS; Daniel SG; McCallum AP; Boehringer AV; Sukhina AS; Zwick RA; Zarnescu DC
    Dis Model Mech; 2013 May; 6(3):721-33. PubMed ID: 23471911
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The ALS disease protein TDP-43 is actively transported in motor neuron axons and regulates axon outgrowth.
    Fallini C; Bassell GJ; Rossoll W
    Hum Mol Genet; 2012 Aug; 21(16):3703-18. PubMed ID: 22641816
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Stress-Specific Spatiotemporal Responses of RNA-Binding Proteins in Human Stem-Cell-Derived Motor Neurons.
    Harley J; Patani R
    Int J Mol Sci; 2020 Nov; 21(21):. PubMed ID: 33172210
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function.
    Murakami T; Qamar S; Lin JQ; Schierle GS; Rees E; Miyashita A; Costa AR; Dodd RB; Chan FT; Michel CH; Kronenberg-Versteeg D; Li Y; Yang SP; Wakutani Y; Meadows W; Ferry RR; Dong L; Tartaglia GG; Favrin G; Lin WL; Dickson DW; Zhen M; Ron D; Schmitt-Ulms G; Fraser PE; Shneider NA; Holt C; Vendruscolo M; Kaminski CF; St George-Hyslop P
    Neuron; 2015 Nov; 88(4):678-90. PubMed ID: 26526393
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Persistent mRNA localization defects and cell death in ALS neurons caused by transient cellular stress.
    Markmiller S; Sathe S; Server KL; Nguyen TB; Fulzele A; Cody N; Javaherian A; Broski S; Finkbeiner S; Bennett EJ; Lécuyer E; Yeo GW
    Cell Rep; 2021 Sep; 36(10):109685. PubMed ID: 34496257
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Stress Induces Dynamic, Cytotoxicity-Antagonizing TDP-43 Nuclear Bodies via Paraspeckle LncRNA NEAT1-Mediated Liquid-Liquid Phase Separation.
    Wang C; Duan Y; Duan G; Wang Q; Zhang K; Deng X; Qian B; Gu J; Ma Z; Zhang S; Guo L; Liu C; Fang Y
    Mol Cell; 2020 Aug; 79(3):443-458.e7. PubMed ID: 32649883
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD.
    Fang MY; Markmiller S; Vu AQ; Javaherian A; Dowdle WE; Jolivet P; Bushway PJ; Castello NA; Baral A; Chan MY; Linsley JW; Linsley D; Mercola M; Finkbeiner S; Lecuyer E; Lewcock JW; Yeo GW
    Neuron; 2019 Sep; 103(5):802-819.e11. PubMed ID: 31272829
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sustained expression of TDP-43 and FUS in motor neurons in rodent's lifetime.
    Huang C; Xia PY; Zhou H
    Int J Biol Sci; 2010 Jul; 6(4):396-406. PubMed ID: 20616880
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phase separation and pathologic transitions of RNP condensates in neurons: implications for amyotrophic lateral sclerosis, frontotemporal dementia and other neurodegenerative disorders.
    Naskar A; Nayak A; Salaikumaran MR; Vishal SS; Gopal PP
    Front Mol Neurosci; 2023; 16():1242925. PubMed ID: 37720552
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pathophysiological implications of RNP granules in frontotemporal dementia and ALS.
    Desai P; Bandopadhyay R
    Neurochem Int; 2020 Nov; 140():104819. PubMed ID: 32763254
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sequence Determinants of TDP-43 Ribonucleoprotein Condensate Formation and Axonal Transport in Neurons.
    Vishal SS; Wijegunawardana D; Salaikumaran MR; Gopal PP
    Front Cell Dev Biol; 2022; 10():876893. PubMed ID: 35646935
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pathological Modification of TDP-43 in Amyotrophic Lateral Sclerosis with SOD1 Mutations.
    Jeon GS; Shim YM; Lee DY; Kim JS; Kang M; Ahn SH; Shin JY; Geum D; Hong YH; Sung JJ
    Mol Neurobiol; 2019 Mar; 56(3):2007-2021. PubMed ID: 29982983
    [TBL] [Abstract][Full Text] [Related]  

  • 19. TDP-43 is directed to stress granules by sorbitol, a novel physiological osmotic and oxidative stressor.
    Dewey CM; Cenik B; Sephton CF; Dries DR; Mayer P; Good SK; Johnson BA; Herz J; Yu G
    Mol Cell Biol; 2011 Mar; 31(5):1098-108. PubMed ID: 21173160
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Human TDP-43 and FUS selectively affect motor neuron maturation and survival in a murine cell model of ALS by non-cell-autonomous mechanisms.
    Wächter N; Storch A; Hermann A
    Amyotroph Lateral Scler Frontotemporal Degener; 2015; 16(7-8):431-41. PubMed ID: 26174443
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 28.