BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

153 related articles for article (PubMed ID: 28271893)

  • 1. MarH, a Bifunctional Enzyme Involved in the Condensation and Hydroxylation Steps of the Marineosin Biosynthetic Pathway.
    Lu W; Kancharla P; Reynolds KA
    Org Lett; 2017 Mar; 19(6):1298-1301. PubMed ID: 28271893
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Elucidation of final steps of the marineosins biosynthetic pathway through identification and characterization of the corresponding gene cluster.
    Salem SM; Kancharla P; Florova G; Gupta S; Lu W; Reynolds KA
    J Am Chem Soc; 2014 Mar; 136(12):4565-74. PubMed ID: 24575817
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Role and substrate specificity of the Streptomyces coelicolor RedH enzyme in undecylprodiginine biosynthesis.
    Haynes SW; Sydor PK; Stanley AE; Song L; Challis GL
    Chem Commun (Camb); 2008 Apr; (16):1865-7. PubMed ID: 18401500
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Elucidation of the Streptomyces coelicolor pathway to 2-undecylpyrrole, a key intermediate in undecylprodiginine and streptorubin B biosynthesis.
    Mo S; Sydor PK; Corre C; Alhamadsheh MM; Stanley AE; Haynes SW; Song L; Reynolds KA; Challis GL
    Chem Biol; 2008 Feb; 15(2):137-48. PubMed ID: 18291318
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Stereospecific synthesis of 23-hydroxyundecylprodiginines and analogues and conversion to antimalarial premarineosins via a Rieske oxygenase catalyzed bicyclization.
    Kancharla P; Lu W; Salem SM; Kelly JX; Reynolds KA
    J Org Chem; 2014 Dec; 79(23):11674-89. PubMed ID: 25380131
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Stereochemistry and Mechanism of Undecylprodigiosin Oxidative Carbocyclization to Streptorubin B by the Rieske Oxygenase RedG.
    Withall DM; Haynes SW; Challis GL
    J Am Chem Soc; 2015 Jun; 137(24):7889-97. PubMed ID: 26023709
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Evaluation of the biosynthetic proposal for the synthesis of marineosins A and B.
    Aldrich LN; Dawson ES; Lindsley CW
    Org Lett; 2010 Mar; 12(5):1048-51. PubMed ID: 20141121
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Site-specific modification of the anticancer and antituberculosis polyether salinomycin by biosynthetic engineering.
    Luhavaya H; Williams SR; Hong H; Gonzaga de Oliveira L; Leadlay PF
    Chembiochem; 2014 Sep; 15(14):2081-5. PubMed ID: 25155178
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Armeniaspirol Antibiotic Biosynthesis: Chlorination and Oxidative Dechlorination Steps Affording Spiro[4.4]non-8-ene.
    Fu C; Xie F; Hoffmann J; Wang Q; Bauer A; Brönstrup M; Mahmud T; Müller R
    Chembiochem; 2019 Mar; 20(6):764-769. PubMed ID: 30556942
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Biosynthesis of the red antibiotic, prodigiosin, in Serratia: identification of a novel 2-methyl-3-n-amyl-pyrrole (MAP) assembly pathway, definition of the terminal condensing enzyme, and implications for undecylprodigiosin biosynthesis in Streptomyces.
    Williamson NR; Simonsen HT; Ahmed RA; Goldet G; Slater H; Woodley L; Leeper FJ; Salmond GP
    Mol Microbiol; 2005 May; 56(4):971-89. PubMed ID: 15853884
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Purification and Kinetic Characterization of the Essential Condensation Enzymes Involved in Prodiginine and Tambjamine Biosynthesis.
    Picott KJ; Deichert JA; deKemp EM; Snieckus V; Ross AC
    Chembiochem; 2020 Apr; 21(7):1036-1042. PubMed ID: 31614061
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Biosynthesis: a twist in the tail.
    Weissman KJ
    Nat Chem Biol; 2011 Jun; 7(7):409-11. PubMed ID: 21685883
    [No Abstract]   [Full Text] [Related]  

  • 13. Rieske non-heme iron-dependent oxygenases catalyse diverse reactions in natural product biosynthesis.
    Perry C; de Los Santos ELC; Alkhalaf LM; Challis GL
    Nat Prod Rep; 2018 Jul; 35(7):622-632. PubMed ID: 29651484
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.
    Li W; Ju J; Rajski SR; Osada H; Shen B
    J Biol Chem; 2008 Oct; 283(42):28607-17. PubMed ID: 18708355
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutasynthesis of pyrrole spiroketal compound using calcimycin 3-hydroxy anthranilic acid biosynthetic mutant.
    Gou L; Wu Q; Lin S; Li X; Liang J; Zhou X; An D; Deng Z; Wang Z
    Appl Microbiol Biotechnol; 2013 Sep; 97(18):8183-91. PubMed ID: 23666477
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Analysis of the prodiginine biosynthesis gene cluster of Streptomyces coelicolor A3(2): new mechanisms for chain initiation and termination in modular multienzymes.
    Cerdeño AM; Bibb MJ; Challis GL
    Chem Biol; 2001 Aug; 8(8):817-29. PubMed ID: 11514230
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Conversion of L-proline to pyrrolyl-2-carboxyl-S-PCP during undecylprodigiosin and pyoluteorin biosynthesis.
    Thomas MG; Burkart MD; Walsh CT
    Chem Biol; 2002 Feb; 9(2):171-84. PubMed ID: 11880032
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure-function analyses of cytochrome P450revI involved in reveromycin A biosynthesis and evaluation of the biological activity of its substrate, reveromycin T.
    Takahashi S; Nagano S; Nogawa T; Kanoh N; Uramoto M; Kawatani M; Shimizu T; Miyazawa T; Shiro Y; Osada H
    J Biol Chem; 2014 Nov; 289(47):32446-58. PubMed ID: 25258320
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Oxidative tailoring reactions catalyzed by nonheme iron-dependent enzymes: streptorubin B biosynthesis as an example.
    Sydor PK; Challis GL
    Methods Enzymol; 2012; 516():195-218. PubMed ID: 23034230
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.
    Li W; Ju J; Osada H; Shen B
    J Bacteriol; 2006 Jun; 188(11):4148-52. PubMed ID: 16707708
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.