BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

143 related articles for article (PubMed ID: 28281900)

  • 1. The emergence of TNIK as a therapeutic target for colorectal cancer.
    Masuda M; Yamada T
    Expert Opin Ther Targets; 2017 Apr; 21(4):353-355. PubMed ID: 28281900
    [No Abstract]   [Full Text] [Related]  

  • 2. Targeting the Wnt signaling pathway in colorectal cancer.
    Sawa M; Masuda M; Yamada T
    Expert Opin Ther Targets; 2016; 20(4):419-29. PubMed ID: 26439805
    [TBL] [Abstract][Full Text] [Related]  

  • 3. TNIK inhibition abrogates colorectal cancer stemness.
    Masuda M; Uno Y; Ohbayashi N; Ohata H; Mimata A; Kukimoto-Niino M; Moriyama H; Kashimoto S; Inoue T; Goto N; Okamoto K; Shirouzu M; Sawa M; Yamada T
    Nat Commun; 2016 Aug; 7():12586. PubMed ID: 27562646
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Traf2- and Nck-interacting kinase is essential for Wnt signaling and colorectal cancer growth.
    Shitashige M; Satow R; Jigami T; Aoki K; Honda K; Shibata T; Ono M; Hirohashi S; Yamada T
    Cancer Res; 2010 Jun; 70(12):5024-33. PubMed ID: 20530691
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Emergence of TNIK inhibitors in cancer therapeutics.
    Yamada T; Masuda M
    Cancer Sci; 2017 May; 108(5):818-823. PubMed ID: 28208209
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Traf2- and Nck-interacting kinase (TNIK) is involved in the anti-cancer mechanism of dovitinib in human multiple myeloma IM-9 cells.
    Chon HJ; Lee Y; Bae KJ; Byun BJ; Kim SA; Kim J
    Amino Acids; 2016 Jul; 48(7):1591-9. PubMed ID: 26995282
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Therapeutic targets in the Wnt signaling pathway: Feasibility of targeting TNIK in colorectal cancer.
    Masuda M; Sawa M; Yamada T
    Pharmacol Ther; 2015 Dec; 156():1-9. PubMed ID: 26542362
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Characterization of the ERG-regulated Kinome in Prostate Cancer Identifies TNIK as a Potential Therapeutic Target.
    Lee RS; Zhang L; Berger A; Lawrence MG; Song J; Niranjan B; Davies RG; Lister NL; Sandhu SK; Rubin MA; Risbridger GP; Taylor RA; Rickman DS; Horvath LG; Daly RJ
    Neoplasia; 2019 Apr; 21(4):389-400. PubMed ID: 30901730
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovery of 3,4-Dihydrobenzo[
    Li Y; Zhang L; Yang R; Qiao Z; Wu M; Huang C; Tian C; Luo X; Yang W; Zhang Y; Li L; Yang S
    J Med Chem; 2022 Feb; 65(3):1786-1807. PubMed ID: 34985886
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synergistic inhibition effect of TNIK inhibitor KY-05009 and receptor tyrosine kinase inhibitor dovitinib on IL-6-induced proliferation and Wnt signaling pathway in human multiple myeloma cells.
    Lee Y; Jung JI; Park KY; Kim SA; Kim J
    Oncotarget; 2017 Jun; 8(25):41091-41101. PubMed ID: 28467797
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Enormous influence of TNIK knockdown on intracellular signals and cell survival.
    Gui J; Yang B; Wu J; Zhou X
    Hum Cell; 2011 Sep; 24(3):121-6. PubMed ID: 21710359
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors.
    Ho KK; Parnell KM; Yuan Y; Xu Y; Kultgen SG; Hamblin S; Hendrickson TF; Luo B; Foulks JM; McCullar MV; Kanner SB
    Bioorg Med Chem Lett; 2013 Jan; 23(2):569-73. PubMed ID: 23232060
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery of benzo[d]oxazol-2(3H)-one derivatives as a new class of TNIK inhibitors for the treatment of colorectal cancer.
    Luo X; Yang R; Li Y; Zhang L; Yang S; Li L
    Bioorg Med Chem Lett; 2022 Jul; 67():128745. PubMed ID: 35447345
    [TBL] [Abstract][Full Text] [Related]  

  • 14. TNIK Is a Therapeutic Target in Lung Squamous Cell Carcinoma and Regulates FAK Activation through Merlin.
    Torres-Ayuso P; An E; Nyswaner KM; Bensen RC; Ritt DA; Specht SI; Das S; Andresson T; Cachau RE; Liang RJ; Ries AL; Robinson CM; Difilippantonio S; Gouker B; Bassel L; Karim BO; Miller CJ; Turk BE; Morrison DK; Brognard J
    Cancer Discov; 2021 Jun; 11(6):1411-1423. PubMed ID: 33495197
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Comprehensive Modeling and Discovery of Mebendazole as a Novel TRAF2- and NCK-interacting Kinase Inhibitor.
    Tan Z; Chen L; Zhang S
    Sci Rep; 2016 Sep; 6():33534. PubMed ID: 27650168
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Nuclear expression of phosphorylated TRAF2- and NCK-interacting kinase in hepatocellular carcinoma is associated with poor prognosis.
    Jin J; Jung HY; Wang Y; Xie J; Yeom YI; Jang JJ; Lee KB
    Pathol Res Pract; 2014 Oct; 210(10):621-7. PubMed ID: 25160513
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Role of the Rap2/TNIK kinase pathway in regulation of LRP6 stability for Wnt signaling.
    Park DS; Seo JH; Hong M; Choi SC
    Biochem Biophys Res Commun; 2013 Jun; 436(2):338-43. PubMed ID: 23743195
    [TBL] [Abstract][Full Text] [Related]  

  • 18. TNIK serves as a novel biomarker associated with poor prognosis in patients with pancreatic cancer.
    Zhang Y; Jiang H; Qin M; Su X; Cao Z; Wang J
    Tumour Biol; 2016 Jan; 37(1):1035-40. PubMed ID: 26269113
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Development of Small Molecules Targeting the Wnt Signaling Pathway in Cancer Stem Cells for the Treatment of Colorectal Cancer.
    Song L; Li Y; He B; Gong Y
    Clin Colorectal Cancer; 2015 Sep; 14(3):133-45. PubMed ID: 25799881
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Therapeutic inhibition of SGK1 suppresses colorectal cancer.
    Liang X; Lan C; Jiao G; Fu W; Long X; An Y; Wang K; Zhou J; Chen T; Li Y; Xu J; Huang Q; Xu B; Xiao J
    Exp Mol Med; 2017 Nov; 49(11):e399. PubMed ID: 29170478
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.