177 related articles for article (PubMed ID: 28285137)
1. Functional analysis of carboxylesterase in human induced pluripotent stem cell-derived enterocytes.
Kabeya T; Matsumura W; Iwao T; Hosokawa M; Matsunaga T
Biochem Biophys Res Commun; 2017 Apr; 486(1):143-148. PubMed ID: 28285137
[TBL] [Abstract][Full Text] [Related]
2. The role of intestinal carboxylesterase in the oral absorption of prodrugs.
Imai T; Ohura K
Curr Drug Metab; 2010 Nov; 11(9):793-805. PubMed ID: 21189138
[TBL] [Abstract][Full Text] [Related]
3. Generation of enterocyte-like cells with pharmacokinetic functions from human induced pluripotent stem cells using small-molecule compounds.
Iwao T; Kodama N; Kondo Y; Kabeya T; Nakamura K; Horikawa T; Niwa T; Kurose K; Matsunaga T
Drug Metab Dispos; 2015 Apr; 43(4):603-10. PubMed ID: 25650381
[TBL] [Abstract][Full Text] [Related]
4. Development of a Caco-2 Cell Line Carrying the Human Intestine-Type CES Expression Profile as a Promising Tool for Ester-Containing Drug Permeability Studies.
Ishizaki Y; Furihata T; Oyama Y; Ohura K; Imai T; Hosokawa M; Akita H; Chiba K
Biol Pharm Bull; 2018; 41(5):697-706. PubMed ID: 29709907
[TBL] [Abstract][Full Text] [Related]
5. Development of a novel system for estimating human intestinal absorption using Caco-2 cells in the absence of esterase activity.
Ohura K; Sakamoto H; Ninomiya S; Imai T
Drug Metab Dispos; 2010 Feb; 38(2):323-31. PubMed ID: 19923255
[TBL] [Abstract][Full Text] [Related]
6. Contribution of carboxylesterase in hamster to the intestinal first-pass loss and low bioavailability of ethyl piperate, an effective lipid-lowering drug candidate.
Lu Y; Bao N; Borjihan G; Ma Y; Hu M; Yu C; Li S; Jia J; Yang D; Wang Y
Drug Metab Dispos; 2011 May; 39(5):796-802. PubMed ID: 21346005
[TBL] [Abstract][Full Text] [Related]
7. [Generation of human iPS cell-derived hepatocytes and enterocytes for application to drug disposition studies].
Iwao T; Matsunaga T
Nihon Yakurigaku Zasshi; 2019; 154(2):72-77. PubMed ID: 31406046
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of mitogen-activated protein kinase kinase, DNA methyltransferase, and transforming growth factor-β promotes differentiation of human induced pluripotent stem cells into enterocytes.
Kodama N; Iwao T; Kabeya T; Horikawa T; Niwa T; Kondo Y; Nakamura K; Matsunaga T
Drug Metab Pharmacokinet; 2016 Jun; 31(3):193-200. PubMed ID: 27161454
[TBL] [Abstract][Full Text] [Related]
9. Differences in Intestinal Hydrolytic Activities between Cynomolgus Monkeys and Humans: Evaluation of Substrate Specificities Using Recombinant Carboxylesterase 2 Isozymes.
Igawa Y; Fujiwara S; Ohura K; Hirokawa T; Nishizawa Y; Uehara S; Uno Y; Imai T
Mol Pharm; 2016 Sep; 13(9):3176-86. PubMed ID: 27454346
[TBL] [Abstract][Full Text] [Related]
10. Pharmacokinetic functions of human induced pluripotent stem cell-derived small intestinal epithelial cells.
Kabeya T; Mima S; Imakura Y; Miyashita T; Ogura I; Yamada T; Yasujima T; Yuasa H; Iwao T; Matsunaga T
Drug Metab Pharmacokinet; 2020 Aug; 35(4):374-382. PubMed ID: 32651148
[TBL] [Abstract][Full Text] [Related]
11. Establishment of a novel culture method for maintaining intestinal stem cells derived from human induced pluripotent stem cells.
Kondo S; Mizuno S; Hashita T; Iwao T; Matsunaga T
Biol Open; 2020 Jan; 9(1):. PubMed ID: 31919043
[TBL] [Abstract][Full Text] [Related]
12. Establishment and Characterization of a Novel Caco-2 Subclone with a Similar Low Expression Level of Human Carboxylesterase 1 to Human Small Intestine.
Ohura K; Nishiyama H; Saco S; Kurokawa K; Imai T
Drug Metab Dispos; 2016 Dec; 44(12):1890-1898. PubMed ID: 27638507
[TBL] [Abstract][Full Text] [Related]
13. Simultaneous Evaluation of Membrane Permeability and UDP-Glucuronosyltransferase-Mediated Metabolism of Food-Derived Compounds Using Human Induced Pluripotent Stem Cell-Derived Small Intestinal Epithelial Cells.
Kitaguchi T; Mizota T; Ito M; Ohno K; Kobayashi K; Ogawa I; Qiu S; Iwao T; Hanioka N; Tanaka M; Matsunaga T
Drug Metab Dispos; 2022 Jan; 50(1):17-23. PubMed ID: 34670778
[TBL] [Abstract][Full Text] [Related]
14. Evaluation of transport mechanism of prodrugs and parent drugs formed by intracellular metabolism in Caco-2 cells with modified carboxylesterase activity: temocapril as a model case.
Ohura K; Nozawa T; Murakami K; Imai T
J Pharm Sci; 2011 Sep; 100(9):3985-94. PubMed ID: 21618543
[TBL] [Abstract][Full Text] [Related]
15. Characteristic Analysis of Intestinal Transport in Enterocyte-Like Cells Differentiated from Human Induced Pluripotent Stem Cells.
Kodama N; Iwao T; Katano T; Ohta K; Yuasa H; Matsunaga T
Drug Metab Dispos; 2016 Oct; 44(10):0. PubMed ID: 27417181
[TBL] [Abstract][Full Text] [Related]
16. Generation of Human iPSC-Derived Intestinal Epithelial Cell Monolayers by CDX2 Transduction.
Takayama K; Negoro R; Yamashita T; Kawai K; Ichikawa M; Mori T; Nakatsu N; Harada K; Ito S; Yamada H; Yamaura Y; Hirata K; Ishida S; Mizuguchi H
Cell Mol Gastroenterol Hepatol; 2019; 8(3):513-526. PubMed ID: 31228606
[TBL] [Abstract][Full Text] [Related]
17. [Utilization of Human iPS Cells for Evaluation of Drug Disposition and Mucosal Damages in the Small Intestine].
Iwao T
Yakugaku Zasshi; 2023; 143(3):243-247. PubMed ID: 36858557
[TBL] [Abstract][Full Text] [Related]
18. Biotransformation Capacity of Carboxylesterase in Skin and Keratinocytes for the Penta-Ethyl Ester Prodrug of DTPA.
Fu J; Sadgrove M; Marson L; Jay M
Drug Metab Dispos; 2016 Aug; 44(8):1313-8. PubMed ID: 27130352
[TBL] [Abstract][Full Text] [Related]
19. Modeling of drug-mediated CYP3A4 induction by using human iPS cell-derived enterocyte-like cells.
Negoro R; Takayama K; Nagamoto Y; Sakurai F; Tachibana M; Mizuguchi H
Biochem Biophys Res Commun; 2016 Apr; 472(4):631-6. PubMed ID: 26966071
[TBL] [Abstract][Full Text] [Related]
20. Substrate specificity of carboxylesterase isozymes and their contribution to hydrolase activity in human liver and small intestine.
Imai T; Taketani M; Shii M; Hosokawa M; Chiba K
Drug Metab Dispos; 2006 Oct; 34(10):1734-41. PubMed ID: 16837570
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]