These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

346 related articles for article (PubMed ID: 28287550)

  • 1. Forskolin-induced Swelling in Intestinal Organoids: An In Vitro Assay for Assessing Drug Response in Cystic Fibrosis Patients.
    Boj SF; Vonk AM; Statia M; Su J; Vries RR; Beekman JM; Clevers H
    J Vis Exp; 2017 Feb; (120):. PubMed ID: 28287550
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterizing responses to CFTR-modulating drugs using rectal organoids derived from subjects with cystic fibrosis.
    Dekkers JF; Berkers G; Kruisselbrink E; Vonk A; de Jonge HR; Janssens HM; Bronsveld I; van de Graaf EA; Nieuwenhuis EE; Houwen RH; Vleggaar FP; Escher JC; de Rijke YB; Majoor CJ; Heijerman HG; de Winter-de Groot KM; Clevers H; van der Ent CK; Beekman JM
    Sci Transl Med; 2016 Jun; 8(344):344ra84. PubMed ID: 27334259
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A functional CFTR assay using primary cystic fibrosis intestinal organoids.
    Dekkers JF; Wiegerinck CL; de Jonge HR; Bronsveld I; Janssens HM; de Winter-de Groot KM; Brandsma AM; de Jong NW; Bijvelds MJ; Scholte BJ; Nieuwenhuis EE; van den Brink S; Clevers H; van der Ent CK; Middendorp S; Beekman JM
    Nat Med; 2013 Jul; 19(7):939-45. PubMed ID: 23727931
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Protocol for Application, Standardization and Validation of the Forskolin-Induced Swelling Assay in Cystic Fibrosis Human Colon Organoids.
    Vonk AM; van Mourik P; Ramalho AS; Silva IAL; Statia M; Kruisselbrink E; Suen SWF; Dekkers JF; Vleggaar FP; Houwen RHJ; Mullenders J; Boj SF; Vries R; Amaral MD; de Boeck K; van der Ent CK; Beekman JM
    STAR Protoc; 2020 Jun; 1(1):100019. PubMed ID: 33111074
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Correction of CFTR function in intestinal organoids to guide treatment of cystic fibrosis.
    Ramalho AS; Fürstová E; Vonk AM; Ferrante M; Verfaillie C; Dupont L; Boon M; Proesmans M; Beekman JM; Sarouk I; Vazquez Cordero C; Vermeulen F; De Boeck K;
    Eur Respir J; 2021 Jan; 57(1):. PubMed ID: 32747394
    [TBL] [Abstract][Full Text] [Related]  

  • 6. β2-Adrenergic receptor agonists activate CFTR in intestinal organoids and subjects with cystic fibrosis.
    Vijftigschild LA; Berkers G; Dekkers JF; Zomer-van Ommen DD; Matthes E; Kruisselbrink E; Vonk A; Hensen CE; Heida-Michel S; Geerdink M; Janssens HM; van de Graaf EA; Bronsveld I; de Winter-de Groot KM; Majoor CJ; Heijerman HG; de Jonge HR; Hanrahan JW; van der Ent CK; Beekman JM
    Eur Respir J; 2016 Sep; 48(3):768-79. PubMed ID: 27471203
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Forskolin-induced swelling of intestinal organoids correlates with disease severity in adults with cystic fibrosis and homozygous F508del mutations.
    de Winter-de Groot KM; Berkers G; Marck-van der Wilt REP; van der Meer R; Vonk A; Dekkers JF; Geerdink M; Michel S; Kruisselbrink E; Vries R; Clevers H; Vleggaar FP; Elias SG; Heijerman HGM; van der Ent CK; Beekman JM
    J Cyst Fibros; 2020 Jul; 19(4):614-619. PubMed ID: 31735562
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Comparison of ex vivo and in vitro intestinal cystic fibrosis models to measure CFTR-dependent ion channel activity.
    Zomer-van Ommen DD; de Poel E; Kruisselbrink E; Oppelaar H; Vonk AM; Janssens HM; van der Ent CK; Hagemeijer MC; Beekman JM
    J Cyst Fibros; 2018 May; 17(3):316-324. PubMed ID: 29544685
    [TBL] [Abstract][Full Text] [Related]  

  • 9. R560S: A class II CFTR mutation that is not rescued by current modulators.
    Awatade NT; Ramalho S; Silva IAL; Felício V; Botelho HM; de Poel E; Vonk A; Beekman JM; Farinha CM; Amaral MD
    J Cyst Fibros; 2019 Mar; 18(2):182-189. PubMed ID: 30030066
    [TBL] [Abstract][Full Text] [Related]  

  • 10. CFTR function and clinical response to modulators parallel nasal epithelial organoid swelling.
    Anderson JD; Liu Z; Odom LV; Kersh L; Guimbellot JS
    Am J Physiol Lung Cell Mol Physiol; 2021 Jul; 321(1):L119-L129. PubMed ID: 34009038
    [TBL] [Abstract][Full Text] [Related]  

  • 11. R117H-CFTR function and response to VX-770 correlate with mRNA and protein expression in intestinal organoids.
    Van Mourik P; van Haaren P; Kruisselbrink E; Korkmaz C; Janssens HM; de Winter-de Groot KM; van der Ent CK; Hagemeijer MC; Beekman JM
    J Cyst Fibros; 2020 Sep; 19(5):728-732. PubMed ID: 32061518
    [TBL] [Abstract][Full Text] [Related]  

  • 12. rAAV-CFTRΔR Rescues the Cystic Fibrosis Phenotype in Human Intestinal Organoids and Cystic Fibrosis Mice.
    Vidović D; Carlon MS; da Cunha MF; Dekkers JF; Hollenhorst MI; Bijvelds MJ; Ramalho AS; Van den Haute C; Ferrante M; Baekelandt V; Janssens HM; De Boeck K; Sermet-Gaudelus I; de Jonge HR; Gijsbers R; Beekman JM; Edelman A; Debyser Z
    Am J Respir Crit Care Med; 2016 Feb; 193(3):288-98. PubMed ID: 26509335
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Functional rescue of CFTR in rectal organoids from patients carrying R334W variant by CFTR modulators and PDE4 inhibitor Roflumilast.
    Latorre RV; Calicchia M; Bigliardi M; Conti J; Kleinfelder K; Melotti P; Sorio C
    Respir Investig; 2024 May; 62(3):455-461. PubMed ID: 38547757
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Potentiator synergy in rectal organoids carrying S1251N, G551D, or F508del CFTR mutations.
    Dekkers JF; Van Mourik P; Vonk AM; Kruisselbrink E; Berkers G; de Winter-de Groot KM; Janssens HM; Bronsveld I; van der Ent CK; de Jonge HR; Beekman JM
    J Cyst Fibros; 2016 Sep; 15(5):568-78. PubMed ID: 27160424
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Forskolin induced swelling (FIS) assay in intestinal organoids to guide eligibility for compassionate use treatment in a CF patient with a rare genotype.
    Aalbers BL; Brunsveld JE; van der Ent CK; van den Eijnden JC; Beekman JM; Heijerman HGM
    J Cyst Fibros; 2022 Mar; 21(2):254-257. PubMed ID: 35110005
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pharmacological analysis of CFTR variants of cystic fibrosis using stem cell-derived organoids.
    Chen KG; Zhong P; Zheng W; Beekman JM
    Drug Discov Today; 2019 Nov; 24(11):2126-2138. PubMed ID: 31173911
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A bioassay using intestinal organoids to measure CFTR modulators in human plasma.
    Dekkers R; Vijftigschild LA; Vonk AM; Kruisselbrink E; de Winter-de Groot KM; Janssens HM; van der Ent CK; Beekman JM
    J Cyst Fibros; 2015 Mar; 14(2):178-81. PubMed ID: 25467948
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Repeatability and reproducibility of the Forskolin-induced swelling (FIS) assay on intestinal organoids from people with Cystic Fibrosis.
    Bierlaagh MC; Ramalho AS; Silva IAL; Vonk AM; van den Bor RM; van Mourik P; Pott J; Suen SWF; Boj SF; Vries RGJ; Lammertyn E; Vermeulen F; Amaral MD; de Boeck K; van der Ent CK; Beekman JM
    J Cyst Fibros; 2024 Jul; 23(4):693-702. PubMed ID: 38749892
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Drug Repurposing for Cystic Fibrosis: Identification of Drugs That Induce CFTR-Independent Fluid Secretion in Nasal Organoids.
    Rodenburg LW; Delpiano L; Railean V; Centeio R; Pinto MC; Smits SMA; van der Windt IS; van Hugten CFJ; van Beuningen SFB; Rodenburg RNP; van der Ent CK; Amaral MD; Kunzelmann K; Gray MA; Beekman JM; Amatngalim GD
    Int J Mol Sci; 2022 Oct; 23(20):. PubMed ID: 36293514
    [TBL] [Abstract][Full Text] [Related]  

  • 20. FDA-approved drug screening in patient-derived organoids demonstrates potential of drug repurposing for rare cystic fibrosis genotypes.
    de Poel E; Spelier S; Hagemeijer MC; van Mourik P; Suen SWF; Vonk AM; Brunsveld JE; Ithakisiou GN; Kruisselbrink E; Oppelaar H; Berkers G; de Winter de Groot KM; Heida-Michel S; Jans SR; van Panhuis H; Bakker M; van der Meer R; Roukema J; Dompeling E; Weersink EJM; Koppelman GH; Blaazer AR; Muijlwijk-Koezen JE; van der Ent CK; Beekman JM
    J Cyst Fibros; 2023 May; 22(3):548-559. PubMed ID: 37147251
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.