BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

237 related articles for article (PubMed ID: 28294316)

  • 1. Knockout of ATG5 leads to malignant cell transformation and resistance to Src family kinase inhibitor PP2.
    Hwang SH; Han BI; Lee M
    J Cell Physiol; 2018 Jan; 233(1):506-515. PubMed ID: 28294316
    [TBL] [Abstract][Full Text] [Related]  

  • 2. An ATG5 knockout promotes paclitaxel resistance in v-Ha-ras-transformed NIH 3T3 cells.
    Eom SY; Hwang SH; Yeom H; Lee M
    Biochem Biophys Res Commun; 2019 May; 513(1):234-241. PubMed ID: 30954217
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Suppression of autophagy sensitizes multidrug resistant cells towards Src tyrosine kinase specific inhibitor PP2.
    Ahn JH; Lee M
    Cancer Lett; 2011 Nov; 310(2):188-97. PubMed ID: 21775053
    [TBL] [Abstract][Full Text] [Related]  

  • 4. EGFR plays a pivotal role in the regulation of polyamine-dependent apoptosis in intestinal epithelial cells.
    Ray RM; Bhattacharya S; Johnson LR
    Cell Signal; 2007 Dec; 19(12):2519-27. PubMed ID: 17825525
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Raf-1 kinase activation is uncoupled from downstream MEK/ERK pathway in cells treated with Src tyrosine kinase inhibitor PP2.
    Lee M
    Biochem Biophys Res Commun; 2006 Nov; 350(2):450-6. PubMed ID: 17010316
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Src family kinase inhibitor PP2 efficiently inhibits cervical cancer cell proliferation through down-regulating phospho-Src-Y416 and phospho-EGFR-Y1173.
    Kong L; Deng Z; Shen H; Zhang Y
    Mol Cell Biochem; 2011 Feb; 348(1-2):11-9. PubMed ID: 21052789
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Levels of the Autophagy-Related 5 Protein Affect Progression and Metastasis of Pancreatic Tumors in Mice.
    Görgülü K; Diakopoulos KN; Ai J; Schoeps B; Kabacaoglu D; Karpathaki AF; Ciecielski KJ; Kaya-Aksoy E; Ruess DA; Berninger A; Kowalska M; Stevanovic M; Wörmann SM; Wartmann T; Zhao Y; Halangk W; Voronina S; Tepikin A; Schlitter AM; Steiger K; Artati A; Adamski J; Aichler M; Walch A; Jastroch M; Hartleben G; Mantzoros CS; Weichert W; Schmid RM; Herzig S; Krüger A; Sainz B; Lesina M; Algül H
    Gastroenterology; 2019 Jan; 156(1):203-217.e20. PubMed ID: 30296435
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of mitotic Aurora kinase A by alisertib induces apoptosis and autophagy of human gastric cancer AGS and NCI-N78 cells.
    Yuan CX; Zhou ZW; Yang YX; He ZX; Zhang X; Wang D; Yang T; Wang NJ; Zhao RJ; Zhou SF
    Drug Des Devel Ther; 2015; 9():487-508. PubMed ID: 25609923
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The investigational Aurora kinase A inhibitor alisertib (MLN8237) induces cell cycle G2/M arrest, apoptosis, and autophagy via p38 MAPK and Akt/mTOR signaling pathways in human breast cancer cells.
    Li JP; Yang YX; Liu QL; Pan ST; He ZX; Zhang X; Yang T; Chen XW; Wang D; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():1627-52. PubMed ID: 25834401
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Induction of autophagy counteracts the anticancer effect of cisplatin in human esophageal cancer cells with acquired drug resistance.
    Yu L; Gu C; Zhong D; Shi L; Kong Y; Zhou Z; Liu S
    Cancer Lett; 2014 Dec; 355(1):34-45. PubMed ID: 25236911
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sorafenib-induced defective autophagy promotes cell death by necroptosis.
    Kharaziha P; Chioureas D; Baltatzis G; Fonseca P; Rodriguez P; Gogvadze V; Lennartsson L; Björklund AC; Zhivotovsky B; Grandér D; Egevad L; Nilsson S; Panaretakis T
    Oncotarget; 2015 Nov; 6(35):37066-82. PubMed ID: 26416459
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway.
    Niu NK; Wang ZL; Pan ST; Ding HQ; Au GH; He ZX; Zhou ZW; Xiao G; Yang YX; Zhang X; Yang T; Chen XW; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():1555-84. PubMed ID: 25792811
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Apoptotic effect of PP2 a Src tyrosine kinase inhibitor, in murine B cell leukemia.
    Lee M; Kim JY; Koh WS
    J Cell Biochem; 2004 Oct; 93(3):629-38. PubMed ID: 15378599
    [TBL] [Abstract][Full Text] [Related]  

  • 14.
    Hwang SH; Yeom H; Lee M
    Korean J Physiol Pharmacol; 2020 May; 24(3):233-240. PubMed ID: 32392914
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Selective pyrrolo-pyrimidine inhibitors reveal a necessary role for Src family kinases in Bcr-Abl signal transduction and oncogenesis.
    Wilson MB; Schreiner SJ; Choi HJ; Kamens J; Smithgall TE
    Oncogene; 2002 Nov; 21(53):8075-88. PubMed ID: 12444544
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dasatinib, a small molecule inhibitor of the Src kinase, reduces the growth and activates apoptosis in pre-neoplastic Barrett's esophagus cell lines: evidence for a noninvasive treatment of high-grade dysplasia.
    Inge LJ; Fowler AJ; Paquette KM; Richer AL; Tran N; Bremner RM
    J Thorac Cardiovasc Surg; 2013 Feb; 145(2):531-8. PubMed ID: 23142123
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Knockout of Atg5 inhibits proliferation and promotes apoptosis of DF-1 cells.
    Liao Z; Dai Z; Cai C; Zhang X; Li A; Zhang H; Yan Y; Lin W; Wu Y; Li H; Li H; Xie Q
    In Vitro Cell Dev Biol Anim; 2019 May; 55(5):341-348. PubMed ID: 31025250
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Alisertib induces cell cycle arrest and autophagy and suppresses epithelial-to-mesenchymal transition involving PI3K/Akt/mTOR and sirtuin 1-mediated signaling pathways in human pancreatic cancer cells.
    Wang F; Li H; Yan XG; Zhou ZW; Yi ZG; He ZX; Pan ST; Yang YX; Wang ZZ; Zhang X; Yang T; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():575-601. PubMed ID: 25632225
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Atg5 knockout induces alternative autophagy via the downregulation of Akt expression.
    Kim HG; Ro MH; Lee M
    Toxicol Res; 2023 Oct; 39(4):637-647. PubMed ID: 37779593
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Knockout of autophagy gene, ATG5 in mice vaginal cells abrogates cytokine response and pathogen clearance during vaginal infection of Candida albicans.
    Shroff A; Sequeira R; Patel V; Reddy KVR
    Cell Immunol; 2018 Feb; 324():59-73. PubMed ID: 29306553
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.