These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

379 related articles for article (PubMed ID: 28315520)

  • 1. Fail-safe control of translation initiation by dissociation of eIF2α phosphorylated ternary complexes.
    Jennings MD; Kershaw CJ; Adomavicius T; Pavitt GD
    Elife; 2017 Mar; 6():. PubMed ID: 28315520
    [TBL] [Abstract][Full Text] [Related]  

  • 2. An eIF5/eIF2 complex antagonizes guanine nucleotide exchange by eIF2B during translation initiation.
    Singh CR; Lee B; Udagawa T; Mohammad-Qureshi SS; Yamamoto Y; Pavitt GD; Asano K
    EMBO J; 2006 Oct; 25(19):4537-46. PubMed ID: 16990799
    [TBL] [Abstract][Full Text] [Related]  

  • 3. eIF2B Mechanisms of Action and Regulation: A Thermodynamic View.
    Bogorad AM; Lin KY; Marintchev A
    Biochemistry; 2018 Mar; 57(9):1426-1435. PubMed ID: 29425030
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The beta/Gcd7 subunit of eukaryotic translation initiation factor 2B (eIF2B), a guanine nucleotide exchange factor, is crucial for binding eIF2 in vivo.
    Dev K; Qiu H; Dong J; Zhang F; Barthlme D; Hinnebusch AG
    Mol Cell Biol; 2010 Nov; 30(21):5218-33. PubMed ID: 20805354
    [TBL] [Abstract][Full Text] [Related]  

  • 5. eIF5 has GDI activity necessary for translational control by eIF2 phosphorylation.
    Jennings MD; Pavitt GD
    Nature; 2010 May; 465(7296):378-81. PubMed ID: 20485439
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tight binding of the phosphorylated alpha subunit of initiation factor 2 (eIF2alpha) to the regulatory subunits of guanine nucleotide exchange factor eIF2B is required for inhibition of translation initiation.
    Krishnamoorthy T; Pavitt GD; Zhang F; Dever TE; Hinnebusch AG
    Mol Cell Biol; 2001 Aug; 21(15):5018-30. PubMed ID: 11438658
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel mechanisms of eIF2B action and regulation by eIF2α phosphorylation.
    Bogorad AM; Lin KY; Marintchev A
    Nucleic Acids Res; 2017 Nov; 45(20):11962-11979. PubMed ID: 29036434
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Biochemical analysis of the eIF2beta gamma complex reveals a structural function for eIF2alpha in catalyzed nucleotide exchange.
    Nika J; Rippel S; Hannig EM
    J Biol Chem; 2001 Jan; 276(2):1051-6. PubMed ID: 11042214
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mechanisms of translational regulation by a human eIF5-mimic protein.
    Singh CR; Watanabe R; Zhou D; Jennings MD; Fukao A; Lee B; Ikeda Y; Chiorini JA; Campbell SG; Ashe MP; Fujiwara T; Wek RC; Pavitt GD; Asano K
    Nucleic Acids Res; 2011 Oct; 39(19):8314-28. PubMed ID: 21745818
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Conserved bipartite motifs in yeast eIF5 and eIF2Bepsilon, GTPase-activating and GDP-GTP exchange factors in translation initiation, mediate binding to their common substrate eIF2.
    Asano K; Krishnamoorthy T; Phan L; Pavitt GD; Hinnebusch AG
    EMBO J; 1999 Mar; 18(6):1673-88. PubMed ID: 10075937
    [TBL] [Abstract][Full Text] [Related]  

  • 11. eIF2B promotes eIF5 dissociation from eIF2*GDP to facilitate guanine nucleotide exchange for translation initiation.
    Jennings MD; Zhou Y; Mohammad-Qureshi SS; Bennett D; Pavitt GD
    Genes Dev; 2013 Dec; 27(24):2696-707. PubMed ID: 24352424
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Change in nutritional status modulates the abundance of critical pre-initiation intermediate complexes during translation initiation in vivo.
    Singh CR; Udagawa T; Lee B; Wassink S; He H; Yamamoto Y; Anderson JT; Pavitt GD; Asano K
    J Mol Biol; 2007 Jul; 370(2):315-30. PubMed ID: 17512538
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Direct binding of translation initiation factor eIF2gamma-G domain to its GTPase-activating and GDP-GTP exchange factors eIF5 and eIF2B epsilon.
    Alone PV; Dever TE
    J Biol Chem; 2006 May; 281(18):12636-44. PubMed ID: 16522633
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural basis for the inhibition of translation through eIF2α phosphorylation.
    Gordiyenko Y; Llácer JL; Ramakrishnan V
    Nat Commun; 2019 Jun; 10(1):2640. PubMed ID: 31201334
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A multifactor complex of eukaryotic initiation factors, eIF1, eIF2, eIF3, eIF5, and initiator tRNA(Met) is an important translation initiation intermediate in vivo.
    Asano K; Clayton J; Shalev A; Hinnebusch AG
    Genes Dev; 2000 Oct; 14(19):2534-46. PubMed ID: 11018020
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The structural basis of translational control by eIF2 phosphorylation.
    Adomavicius T; Guaita M; Zhou Y; Jennings MD; Latif Z; Roseman AM; Pavitt GD
    Nat Commun; 2019 May; 10(1):2136. PubMed ID: 31086188
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of domains and residues within the epsilon subunit of eukaryotic translation initiation factor 2B (eIF2Bepsilon) required for guanine nucleotide exchange reveals a novel activation function promoted by eIF2B complex formation.
    Gomez E; Pavitt GD
    Mol Cell Biol; 2000 Jun; 20(11):3965-76. PubMed ID: 10805739
    [TBL] [Abstract][Full Text] [Related]  

  • 18. eIF2 independently binds two distinct eIF2B subcomplexes that catalyze and regulate guanine-nucleotide exchange.
    Pavitt GD; Ramaiah KV; Kimball SR; Hinnebusch AG
    Genes Dev; 1998 Feb; 12(4):514-26. PubMed ID: 9472020
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dynamic cycling of eIF2 through a large eIF2B-containing cytoplasmic body: implications for translation control.
    Campbell SG; Hoyle NP; Ashe MP
    J Cell Biol; 2005 Sep; 170(6):925-34. PubMed ID: 16157703
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Crystal structure of eIF2B and insights into eIF2-eIF2B interactions.
    Kashiwagi K; Ito T; Yokoyama S
    FEBS J; 2017 Mar; 284(6):868-874. PubMed ID: 27627185
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.