These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 28317242)

  • 1. Chemical screening identifies ROCK as a target for recovering mitochondrial function in Hutchinson-Gilford progeria syndrome.
    Kang HT; Park JT; Choi K; Choi HJC; Jung CW; Kim GR; Lee YS; Park SC
    Aging Cell; 2017 Jun; 16(3):541-550. PubMed ID: 28317242
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A crucial role of ROCK for alleviation of senescence-associated phenotype.
    Park JT; Kang HT; Park CH; Lee YS; Cho KA; Park SC
    Exp Gerontol; 2018 Jun; 106():8-15. PubMed ID: 29474864
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Rescue of Mitochondrial Function in Hutchinson-Gilford Progeria Syndrome by the Pharmacological Modulation of Exportin CRM1.
    Monterrubio-Ledezma F; Navarro-García F; Massieu L; Mondragón-Flores R; Soto-Ponce LA; Magaña JJ; Cisneros B
    Cells; 2023 Jan; 12(2):. PubMed ID: 36672210
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The accumulation of un-repairable DNA damage in laminopathy progeria fibroblasts is caused by ROS generation and is prevented by treatment with N-acetyl cysteine.
    Richards SA; Muter J; Ritchie P; Lattanzi G; Hutchison CJ
    Hum Mol Genet; 2011 Oct; 20(20):3997-4004. PubMed ID: 21807766
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Methylene blue alleviates nuclear and mitochondrial abnormalities in progeria.
    Xiong ZM; Choi JY; Wang K; Zhang H; Tariq Z; Wu D; Ko E; LaDana C; Sesaki H; Cao K
    Aging Cell; 2016 Apr; 15(2):279-90. PubMed ID: 26663466
    [TBL] [Abstract][Full Text] [Related]  

  • 6. High-Throughput Screen Detects Calcium Signaling Dysfunction in Hutchinson-Gilford Progeria Syndrome.
    Fafián-Labora JA; Morente-López M; de Toro FJ; Arufe MC
    Int J Mol Sci; 2021 Jul; 22(14):. PubMed ID: 34298947
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effect of progerin on the accumulation of oxidized proteins in fibroblasts from Hutchinson Gilford progeria patients.
    Viteri G; Chung YW; Stadtman ER
    Mech Ageing Dev; 2010 Jan; 131(1):2-8. PubMed ID: 19958786
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Signaling pathway activation drift during aging: Hutchinson-Gilford Progeria Syndrome fibroblasts are comparable to normal middle-age and old-age cells.
    Aliper AM; Csoka AB; Buzdin A; Jetka T; Roumiantsev S; Moskalev A; Zhavoronkov A
    Aging (Albany NY); 2015 Jan; 7(1):26-37. PubMed ID: 25587796
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Peroxisomal abnormalities and catalase deficiency in Hutchinson-Gilford Progeria Syndrome.
    Mao X; Bharti P; Thaivalappil A; Cao K
    Aging (Albany NY); 2020 Mar; 12(6):5195-5208. PubMed ID: 32186522
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lysophosphatidic acid receptor LPA
    Chen WM; Chiang JC; Lin YC; Lin YN; Chuang PY; Chang YC; Chen CC; Wu KY; Hsieh JC; Chen SK; Huang WP; Chen BPC; Lee H
    Aging Cell; 2020 Jan; 19(1):e13064. PubMed ID: 31714004
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Temsirolimus Partially Rescues the Hutchinson-Gilford Progeria Cellular Phenotype.
    Gabriel D; Gordon LB; Djabali K
    PLoS One; 2016; 11(12):e0168988. PubMed ID: 28033363
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Defective DSB repair correlates with abnormal nuclear morphology and is improved with FTI treatment in Hutchinson-Gilford progeria syndrome fibroblasts.
    Constantinescu D; Csoka AB; Navara CS; Schatten GP
    Exp Cell Res; 2010 Oct; 316(17):2747-59. PubMed ID: 20599958
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pretreatment with Rho-kinase inhibitor ameliorates lethal endotoxemia-induced liver injury by improving mitochondrial function.
    Ding R; Han J; Zhao D; Hu Z; Ma X
    Int Immunopharmacol; 2016 Nov; 40():125-130. PubMed ID: 27588912
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sustained accumulation of prelamin A and depletion of lamin A/C both cause oxidative stress and mitochondrial dysfunction but induce different cell fates.
    Sieprath T; Corne TD; Nooteboom M; Grootaert C; Rajkovic A; Buysschaert B; Robijns J; Broers JL; Ramaekers FC; Koopman WJ; Willems PH; De Vos WH
    Nucleus; 2015; 6(3):236-46. PubMed ID: 25996284
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Prolonged treatment with Y-27632 promotes the senescence of primary human dermal fibroblasts by increasing the expression of IGFBP-5 and transforming them into a CAF-like phenotype.
    Li X; Zhou Q; Wang S; Wang P; Li J; Xie Z; Liu C; Wen J; Wu X
    Aging (Albany NY); 2020 Aug; 12(16):16621-16646. PubMed ID: 32843583
    [TBL] [Abstract][Full Text] [Related]  

  • 16. S1PR2 antagonist ameliorate high glucose-induced fission and dysfunction of mitochondria in HRGECs via regulating ROCK1.
    Chen W; Xiang H; Chen R; Yang J; Yang X; Zhou J; Liu H; Zhao S; Xiao J; Chen P; Chen AF; Chen S; Lu H
    BMC Nephrol; 2019 Apr; 20(1):135. PubMed ID: 30999892
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Incomplete processing of mutant lamin A in Hutchinson-Gilford progeria leads to nuclear abnormalities, which are reversed by farnesyltransferase inhibition.
    Glynn MW; Glover TW
    Hum Mol Genet; 2005 Oct; 14(20):2959-69. PubMed ID: 16126733
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome.
    Scaffidi P; Misteli T
    Nat Med; 2005 Apr; 11(4):440-5. PubMed ID: 15750600
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Progerin impairs chromosome maintenance by depleting CENP-F from metaphase kinetochores in Hutchinson-Gilford progeria fibroblasts.
    Eisch V; Lu X; Gabriel D; Djabali K
    Oncotarget; 2016 Apr; 7(17):24700-18. PubMed ID: 27015553
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mitophagy defect mediates the aging-associated hallmarks in Hutchinson-Gilford progeria syndrome.
    Sun Y; Xu L; Li Y; Jia S; Wang G; Cen X; Xu Y; Cao Z; Wang J; Shen N; Hu L; Zhang J; Mao J; Xia H; Liu Z; Fu X
    Aging Cell; 2024 Jun; 23(6):e14143. PubMed ID: 38482753
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.