BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

689 related articles for article (PubMed ID: 28318036)

  • 1. Autophagy determines efficiency of liver-directed gene therapy with adeno-associated viral vectors.
    Hösel M; Huber A; Bohlen S; Lucifora J; Ronzitti G; Puzzo F; Boisgerault F; Hacker UT; Kwanten WJ; Klöting N; Blüher M; Gluschko A; Schramm M; Utermöhlen O; Bloch W; Mingozzi F; Krut O; Büning H
    Hepatology; 2017 Jul; 66(1):252-265. PubMed ID: 28318036
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Gene transfer into hepatocytes mediated by helper virus-free HSV/AAV hybrid vectors.
    Fraefel C; Jacoby DR; Lage C; Hilderbrand H; Chou JY; Alt FW; Breakefield XO; Majzoub JA
    Mol Med; 1997 Dec; 3(12):813-25. PubMed ID: 9440115
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Improved hepatic gene transfer by using an adeno-associated virus serotype 5 vector.
    Mingozzi F; Schüttrumpf J; Arruda VR; Liu Y; Liu YL; High KA; Xiao W; Herzog RW
    J Virol; 2002 Oct; 76(20):10497-502. PubMed ID: 12239326
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Optimized adeno-associated virus (AAV)-protein phosphatase-5 helper viruses for efficient liver transduction by single-stranded AAV vectors: therapeutic expression of factor IX at reduced vector doses.
    Jayandharan GR; Zhong L; Sack BK; Rivers AE; Li M; Li B; Herzog RW; Srivastava A
    Hum Gene Ther; 2010 Mar; 21(3):271-83. PubMed ID: 19788390
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Selection and evaluation of clinically relevant AAV variants in a xenograft liver model.
    Lisowski L; Dane AP; Chu K; Zhang Y; Cunningham SC; Wilson EM; Nygaard S; Grompe M; Alexander IE; Kay MA
    Nature; 2014 Feb; 506(7488):382-6. PubMed ID: 24390344
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Adeno-associated viral vectors for correction of inborn errors of metabolism: progressing towards clinical application.
    Jacobs F; Wang L
    Curr Pharm Des; 2011; 17(24):2500-15. PubMed ID: 21774772
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A limited number of transducible hepatocytes restricts a wide-range linear vector dose response in recombinant adeno-associated virus-mediated liver transduction.
    Nakai H; Thomas CE; Storm TA; Fuess S; Powell S; Wright JF; Kay MA
    J Virol; 2002 Nov; 76(22):11343-9. PubMed ID: 12388694
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification and Validation of Small Molecules That Enhance Recombinant Adeno-associated Virus Transduction following High-Throughput Screens.
    Nicolson SC; Li C; Hirsch ML; Setola V; Samulski RJ
    J Virol; 2016 Aug; 90(16):7019-7031. PubMed ID: 27147738
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Self-complementary adeno-associated virus 2 (AAV)-T cell protein tyrosine phosphatase vectors as helper viruses to improve transduction efficiency of conventional single-stranded AAV vectors in vitro and in vivo.
    Zhong L; Chen L; Li Y; Qing K; Weigel-Kelley KA; Chan RJ; Yoder MC; Srivastava A
    Mol Ther; 2004 Nov; 10(5):950-7. PubMed ID: 15509512
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Single-Cell Transcriptome Analysis of Mouse Liver Cell-Specific Tropism and Transcriptional Dysregulation Following Intravenous Administration of AAVrh.10 Vectors.
    Zhu D; Rostami MR; Zuo WL; Leopold PL; Crystal RG
    Hum Gene Ther; 2020 May; 31(9-10):590-604. PubMed ID: 32143547
    [TBL] [Abstract][Full Text] [Related]  

  • 11. AAV-mediated liver-directed gene therapy.
    Sands MS
    Methods Mol Biol; 2011; 807():141-57. PubMed ID: 22034029
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Development of a Clinical Candidate AAV3 Vector for Gene Therapy of Hemophilia B.
    Brown HC; Doering CB; Herzog RW; Ling C; Markusic DM; Spencer HT; Srivastava A; Srivastava A
    Hum Gene Ther; 2020 Oct; 31(19-20):1114-1123. PubMed ID: 32657150
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Long-Term Follow-Up of the First in Human Intravascular Delivery of AAV for Gene Transfer: AAV2-hFIX16 for Severe Hemophilia B.
    George LA; Ragni MV; Rasko JEJ; Raffini LJ; Samelson-Jones BJ; Ozelo M; Hazbon M; Runowski AR; Wellman JA; Wachtel K; Chen Y; Anguela XM; Kuranda K; Mingozzi F; High KA
    Mol Ther; 2020 Sep; 28(9):2073-2082. PubMed ID: 32559433
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Enhancing Transgene Expression from Recombinant AAV8 Vectors in Different Tissues Using Woodchuck Hepatitis Virus Post-Transcriptional Regulatory Element.
    Wang L; Wang Z; Zhang F; Zhu R; Bi J; Wu J; Zhang H; Wu H; Kong W; Yu B; Yu X
    Int J Med Sci; 2016; 13(4):286-91. PubMed ID: 27076785
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Enhancing transduction of the liver by adeno-associated viral vectors.
    Nathwani AC; Cochrane M; McIntosh J; Ng CY; Zhou J; Gray JT; Davidoff AM
    Gene Ther; 2009 Jan; 16(1):60-9. PubMed ID: 18701909
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Engineered AAV vector minimizes in vivo targeting of transduced hepatocytes by capsid-specific CD8+ T cells.
    Martino AT; Basner-Tschakarjan E; Markusic DM; Finn JD; Hinderer C; Zhou S; Ostrov DA; Srivastava A; Ertl HC; Terhorst C; High KA; Mingozzi F; Herzog RW
    Blood; 2013 Mar; 121(12):2224-33. PubMed ID: 23325831
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Adeno-associated virus type 2-mediated gene transfer: role of cellular T-cell protein tyrosine phosphatase in transgene expression in established cell lines in vitro and transgenic mice in vivo.
    Qing K; Li W; Zhong L; Tan M; Hansen J; Weigel-Kelley KA; Chen L; Yoder MC; Srivastava A
    J Virol; 2003 Feb; 77(4):2741-6. PubMed ID: 12552015
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Nonrandom transduction of recombinant adeno-associated virus vectors in mouse hepatocytes in vivo: cell cycling does not influence hepatocyte transduction.
    Miao CH; Nakai H; Thompson AR; Storm TA; Chiu W; Snyder RO; Kay MA
    J Virol; 2000 Apr; 74(8):3793-803. PubMed ID: 10729154
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evaluation of engineered AAV capsids for hepatic factor IX gene transfer in murine and canine models.
    Markusic DM; Nichols TC; Merricks EP; Palaschak B; Zolotukhin I; Marsic D; Zolotukhin S; Srivastava A; Herzog RW
    J Transl Med; 2017 May; 15(1):94. PubMed ID: 28460646
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Double-stranded RNA innate immune response activation from long-term adeno-associated virus vector transduction.
    Shao W; Earley LF; Chai Z; Chen X; Sun J; He T; Deng M; Hirsch ML; Ting J; Samulski RJ; Li C
    JCI Insight; 2018 Jun; 3(12):. PubMed ID: 29925692
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 35.