365 related articles for article (PubMed ID: 28319438)
1. Systemic deregulation of autophagy upon loss of ALS- and FTD-linked C9orf72.
Ji YJ; Ugolino J; Brady NR; Hamacher-Brady A; Wang J
Autophagy; 2017 Jul; 13(7):1254-1255. PubMed ID: 28319438
[TBL] [Abstract][Full Text] [Related]
2. Loss of C9orf72 Enhances Autophagic Activity via Deregulated mTOR and TFEB Signaling.
Ugolino J; Ji YJ; Conchina K; Chu J; Nirujogi RS; Pandey A; Brady NR; Hamacher-Brady A; Wang J
PLoS Genet; 2016 Nov; 12(11):e1006443. PubMed ID: 27875531
[TBL] [Abstract][Full Text] [Related]
3.
Shao Q; Yang M; Liang C; Ma L; Zhang W; Jiang Z; Luo J; Lee JK; Liang C; Chen JF
Autophagy; 2020 Sep; 16(9):1635-1650. PubMed ID: 31847700
[TBL] [Abstract][Full Text] [Related]
4. C9orf72 ALS-FTD: recent evidence for dysregulation of the autophagy-lysosome pathway at multiple levels.
Beckers J; Tharkeshwar AK; Van Damme P
Autophagy; 2021 Nov; 17(11):3306-3322. PubMed ID: 33632058
[TBL] [Abstract][Full Text] [Related]
5. A C9ORF72/SMCR8-containing complex regulates ULK1 and plays a dual role in autophagy.
Yang M; Liang C; Swaminathan K; Herrlinger S; Lai F; Shiekhattar R; Chen JF
Sci Adv; 2016 Sep; 2(9):e1601167. PubMed ID: 27617292
[TBL] [Abstract][Full Text] [Related]
6. The most prevalent genetic cause of ALS-FTD, C9orf72 synergizes the toxicity of ATXN2 intermediate polyglutamine repeats through the autophagy pathway.
Ciura S; Sellier C; Campanari ML; Charlet-Berguerand N; Kabashi E
Autophagy; 2016 Aug; 12(8):1406-8. PubMed ID: 27245636
[TBL] [Abstract][Full Text] [Related]
7. Cellular and physiological functions of C9ORF72 and implications for ALS/FTD.
Pang W; Hu F
J Neurochem; 2021 May; 157(3):334-350. PubMed ID: 33259633
[TBL] [Abstract][Full Text] [Related]
8. SMCR8 negatively regulates AKT and MTORC1 signaling to modulate lysosome biogenesis and tissue homeostasis.
Lan Y; Sullivan PM; Hu F
Autophagy; 2019 May; 15(5):871-885. PubMed ID: 30696333
[TBL] [Abstract][Full Text] [Related]
9. TFEB/Mitf links impaired nuclear import to autophagolysosomal dysfunction in C9-ALS.
Cunningham KM; Maulding K; Ruan K; Senturk M; Grima JC; Sung H; Zuo Z; Song H; Gao J; Dubey S; Rothstein JD; Zhang K; Bellen HJ; Lloyd TE
Elife; 2020 Dec; 9():. PubMed ID: 33300868
[TBL] [Abstract][Full Text] [Related]
10. The ALS-FTD-linked gene product, C9orf72, regulates neuronal morphogenesis via autophagy.
Ho WY; Tai YK; Chang JC; Liang J; Tyan SH; Chen S; Guan JL; Zhou H; Shen HM; Koo E; Ling SC
Autophagy; 2019 May; 15(5):827-842. PubMed ID: 30669939
[TBL] [Abstract][Full Text] [Related]
11. The progress in
Jiang L; Zhang T; Lu K; Qi S
Small GTPases; 2022 Jan; 13(1):56-76. PubMed ID: 33663328
[TBL] [Abstract][Full Text] [Related]
12. Smcr8 deficiency disrupts axonal transport-dependent lysosomal function and promotes axonal swellings and gain of toxicity in C9ALS/FTD mouse models.
Liang C; Shao Q; Zhang W; Yang M; Chang Q; Chen R; Chen JF
Hum Mol Genet; 2019 Dec; 28(23):3940-3953. PubMed ID: 31625563
[TBL] [Abstract][Full Text] [Related]
13. C9orf72-dependent lysosomal functions regulate epigenetic control of autophagy and lipid metabolism.
Liu Y; Wang J
Autophagy; 2019 May; 15(5):913-914. PubMed ID: 30767689
[TBL] [Abstract][Full Text] [Related]
14. Structure of the C9orf72 ARF GAP complex that is haploinsufficient in ALS and FTD.
Su MY; Fromm SA; Zoncu R; Hurley JH
Nature; 2020 Sep; 585(7824):251-255. PubMed ID: 32848248
[TBL] [Abstract][Full Text] [Related]
15. The C9orf72-interacting protein Smcr8 is a negative regulator of autoimmunity and lysosomal exocytosis.
Zhang Y; Burberry A; Wang JY; Sandoe J; Ghosh S; Udeshi ND; Svinkina T; Mordes DA; Mok J; Charlton M; Li QZ; Carr SA; Eggan K
Genes Dev; 2018 Jul; 32(13-14):929-943. PubMed ID: 29950492
[TBL] [Abstract][Full Text] [Related]
16. Cryo-EM structure of C9ORF72-SMCR8-WDR41 reveals the role as a GAP for Rab8a and Rab11a.
Tang D; Sheng J; Xu L; Zhan X; Liu J; Jiang H; Shu X; Liu X; Zhang T; Jiang L; Zhou C; Li W; Cheng W; Li Z; Wang K; Lu K; Yan C; Qi S
Proc Natl Acad Sci U S A; 2020 May; 117(18):9876-9883. PubMed ID: 32303654
[TBL] [Abstract][Full Text] [Related]
17. Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin-2 to induce motor neuron dysfunction and cell death.
Sellier C; Campanari ML; Julie Corbier C; Gaucherot A; Kolb-Cheynel I; Oulad-Abdelghani M; Ruffenach F; Page A; Ciura S; Kabashi E; Charlet-Berguerand N
EMBO J; 2016 Jun; 35(12):1276-97. PubMed ID: 27103069
[TBL] [Abstract][Full Text] [Related]
18. Reversing lysosome-ribosome circuit dysregulation mitigates C9FTD/ALS neurodegeneration and behaviors.
Ma L; Liang C; Wang J; Chang Q; Wang Y; Zhang W; Du Y; Sadan J; Chen JF
Hum Mol Genet; 2023 Apr; 32(8):1252-1265. PubMed ID: 36322143
[TBL] [Abstract][Full Text] [Related]
19. [Impact of C9orf72 on Japanese Patients with Amytrophic Lateral Sclerosis (ALS)/Frontotemporal Dementia (FTD)].
Tomiyama H
Brain Nerve; 2019 Nov; 71(11):1190-1208. PubMed ID: 31722305
[TBL] [Abstract][Full Text] [Related]
20. Nucleoporin POM121 signals TFEB-mediated autophagy via activation of SIGMAR1/sigma-1 receptor chaperone by pridopidine.
Wang SM; Wu HE; Yasui Y; Geva M; Hayden M; Maurice T; Cozzolino M; Su TP
Autophagy; 2023 Jan; 19(1):126-151. PubMed ID: 35507432
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]