BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

263 related articles for article (PubMed ID: 28319892)

  • 1. Mitochondrial hyperpolarization in iPSC-derived neurons from patients of FTDP-17 with 10+16 MAPT mutation leads to oxidative stress and neurodegeneration.
    Esteras N; Rohrer JD; Hardy J; Wray S; Abramov AY
    Redox Biol; 2017 Aug; 12():410-422. PubMed ID: 28319892
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Frontotemporal dementia-associated N279K tau mutant disrupts subcellular vesicle trafficking and induces cellular stress in iPSC-derived neural stem cells.
    Wren MC; Zhao J; Liu CC; Murray ME; Atagi Y; Davis MD; Fu Y; Okano HJ; Ogaki K; Strongosky AJ; Tacik P; Rademakers R; Ross OA; Dickson DW; Wszolek ZK; Kanekiyo T; Bu G
    Mol Neurodegener; 2015 Sep; 10():46. PubMed ID: 26373282
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Genetically engineered MAPT 10+16 mutation causes pathophysiological excitability of human iPSC-derived neurons related to 4R tau-induced dementia.
    Kopach O; Esteras N; Wray S; Abramov AY; Rusakov DA
    Cell Death Dis; 2021 Jul; 12(8):716. PubMed ID: 34274950
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Developmental regulation of tau splicing is disrupted in stem cell-derived neurons from frontotemporal dementia patients with the 10 + 16 splice-site mutation in MAPT.
    Sposito T; Preza E; Mahoney CJ; Setó-Salvia N; Ryan NS; Morris HR; Arber C; Devine MJ; Houlden H; Warner TT; Bushell TJ; Zagnoni M; Kunath T; Livesey FJ; Fox NC; Rossor MN; Hardy J; Wray S
    Hum Mol Genet; 2015 Sep; 24(18):5260-9. PubMed ID: 26136155
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MMP-9 and MMP-2 Contribute to Neuronal Cell Death in iPSC Models of Frontotemporal Dementia with MAPT Mutations.
    Biswas MHU; Almeida S; Lopez-Gonzalez R; Mao W; Zhang Z; Karydas A; Geschwind MD; Biernat J; Mandelkow EM; Futai K; Miller BL; Gao FB
    Stem Cell Reports; 2016 Sep; 7(3):316-324. PubMed ID: 27594586
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Early maturation and distinct tau pathology in induced pluripotent stem cell-derived neurons from patients with MAPT mutations.
    Iovino M; Agathou S; González-Rueda A; Del Castillo Velasco-Herrera M; Borroni B; Alberici A; Lynch T; O'Dowd S; Geti I; Gaffney D; Vallier L; Paulsen O; Káradóttir RT; Spillantini MG
    Brain; 2015 Nov; 138(Pt 11):3345-59. PubMed ID: 26220942
    [TBL] [Abstract][Full Text] [Related]  

  • 7. MAPT genotype-dependent mitochondrial aberration and ROS production trigger dysfunction and death in cortical neurons of patients with hereditary FTLD.
    Korn L; Speicher AM; Schroeter CB; Gola L; Kaehne T; Engler A; Disse P; Fernández-Orth J; Csatári J; Naumann M; Seebohm G; Meuth SG; Schöler HR; Wiendl H; Kovac S; Pawlowski M
    Redox Biol; 2023 Feb; 59():102597. PubMed ID: 36599286
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Tau inhibits mitochondrial calcium efflux and makes neurons vulnerable to calcium-induced cell death.
    Britti E; Ros J; Esteras N; Abramov AY
    Cell Calcium; 2020 Mar; 86():102150. PubMed ID: 31918031
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Distinct Neurodegenerative Changes in an Induced Pluripotent Stem Cell Model of Frontotemporal Dementia Linked to Mutant TAU Protein.
    Ehrlich M; Hallmann AL; Reinhardt P; Araúzo-Bravo MJ; Korr S; Röpke A; Psathaki OE; Ehling P; Meuth SG; Oblak AL; Murrell JR; Ghetti B; Zaehres H; Schöler HR; Sterneckert J; Kuhlmann T; Hargus G
    Stem Cell Reports; 2015 Jul; 5(1):83-96. PubMed ID: 26143746
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mitochondrial ROS control neuronal excitability and cell fate in frontotemporal dementia.
    Esteras N; Kopach O; Maiolino M; Lariccia V; Amoroso S; Qamar S; Wray S; Rusakov DA; Jaganjac M; Abramov AY
    Alzheimers Dement; 2022 Feb; 18(2):318-338. PubMed ID: 34057756
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Human iPSC-Derived Neuronal Model of Tau-A152T Frontotemporal Dementia Reveals Tau-Mediated Mechanisms of Neuronal Vulnerability.
    Silva MC; Cheng C; Mair W; Almeida S; Fong H; Biswas MHU; Zhang Z; Huang Y; Temple S; Coppola G; Geschwind DH; Karydas A; Miller BL; Kosik KS; Gao FB; Steen JA; Haggarty SJ
    Stem Cell Reports; 2016 Sep; 7(3):325-340. PubMed ID: 27594585
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Induced pluripotent stem cells (iPSCs) derived from a symptomatic carrier of a S305I mutation in the microtubule-associated protein tau (MAPT)-gene causing frontotemporal dementia.
    Nimsanor N; Jørring I; Rasmussen MA; Clausen C; Mau-Holzmann UA; Kitiyanant N; Nielsen JE; Nielsen TT; Hyttel P; Holst B; Schmid B
    Stem Cell Res; 2016 Nov; 17(3):564-567. PubMed ID: 27789411
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [The genetics of dementias. Part 1: Molecular basis of frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17)].
    Kowalska A
    Postepy Hig Med Dosw (Online); 2009 Jun; 63():278-86. PubMed ID: 19535823
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Generation of an isogenic, gene-corrected iPSC line from a symptomatic 59-year-old female patient with frontotemporal dementia caused by an R406W mutation in the microtubule associated protein tau (MAPT) gene.
    Nimsanor N; Poulsen U; Rasmussen MA; Clausen C; Mau-Holzmann UA; Nielsen JE; Nielsen TT; Hyttel P; Holst B; Schmid B
    Stem Cell Res; 2016 Nov; 17(3):576-579. PubMed ID: 27934586
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Maturation and phenotype of pathophysiological neuronal excitability of human cells in tau-related dementia.
    Kopach O; Esteras N; Wray S; Rusakov DA; Abramov AY
    J Cell Sci; 2020 May; 133(10):. PubMed ID: 32299835
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Clinical, pathological, and genetic characteristics of frontotemporal dementia and parkinsonism linked to chromosome 17 with mutations in the MAPT and PGRN].
    Tsuboi Y
    Brain Nerve; 2009 Nov; 61(11):1285-91. PubMed ID: 19938685
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pathological Progression Induced by the Frontotemporal Dementia-Associated R406W Tau Mutation in Patient-Derived iPSCs.
    Nakamura M; Shiozawa S; Tsuboi D; Amano M; Watanabe H; Maeda S; Kimura T; Yoshimatsu S; Kisa F; Karch CM; Miyasaka T; Takashima A; Sahara N; Hisanaga SI; Ikeuchi T; Kaibuchi K; Okano H
    Stem Cell Reports; 2019 Oct; 13(4):684-699. PubMed ID: 31543469
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B.
    Zhang Y; Schmid B; Nikolaisen NK; Rasmussen MA; Aldana BI; Agger M; Calloe K; Stummann TC; Larsen HM; Nielsen TT; Huang J; Xu F; Liu X; Bolund L; Meyer M; Bak LK; Waagepetersen HS; Luo Y; Nielsen JE; ; Holst B; Clausen C; Hyttel P; Freude KK
    Stem Cell Reports; 2017 Mar; 8(3):648-658. PubMed ID: 28216144
    [TBL] [Abstract][Full Text] [Related]  

  • 19. FTDP-17 with Pick body-like inclusions associated with a novel tau mutation, p.E372G.
    Tacik P; DeTure MA; Carlomagno Y; Lin WL; Murray ME; Baker MC; Josephs KA; Boeve BF; Wszolek ZK; Graff-Radford NR; Parisi JE; Petrucelli L; Rademakers R; Isaacson RS; Heilman KM; Petersen RC; Dickson DW; Kouri N
    Brain Pathol; 2017 Sep; 27(5):612-626. PubMed ID: 27529406
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Astrocyte pathology in a human neural stem cell model of frontotemporal dementia caused by mutant TAU protein.
    Hallmann AL; Araúzo-Bravo MJ; Mavrommatis L; Ehrlich M; Röpke A; Brockhaus J; Missler M; Sterneckert J; Schöler HR; Kuhlmann T; Zaehres H; Hargus G
    Sci Rep; 2017 Mar; 7():42991. PubMed ID: 28256506
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.