These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

141 related articles for article (PubMed ID: 28321016)

  • 1. 4μ8C Inhibits Insulin Secretion Independent of IRE1α RNase Activity.
    Sato H; Shiba Y; Tsuchiya Y; Saito M; Kohno K
    Cell Struct Funct; 2017 May; 42(1):61-70. PubMed ID: 28321016
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Treatment of established TH2 cells with 4μ8c, an inhibitor of IRE1α, blocks IL-5 but not IL-4 secretion.
    Poe C; Youngblood C; Hodge K; Kemp K
    BMC Immunol; 2019 Jan; 20(1):3. PubMed ID: 30630412
    [TBL] [Abstract][Full Text] [Related]  

  • 3. IRE1α-XBP1 pathway promotes melanoma progression by regulating IL-6/STAT3 signaling.
    Chen C; Zhang X
    J Transl Med; 2017 Feb; 15(1):42. PubMed ID: 28222747
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ER stress and distinct outputs of the IRE1α RNase control proliferation and senescence in response to oncogenic Ras.
    Blazanin N; Son J; Craig-Lucas AB; John CL; Breech KJ; Podolsky MA; Glick AB
    Proc Natl Acad Sci U S A; 2017 Sep; 114(37):9900-9905. PubMed ID: 28847931
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Unfolded Protein Response Reveals eIF2α Phosphorylation as a Critical Factor for Direct MHC Class I Antigen Presentation.
    Nagamine BS; Godil J; Dolan BP
    Immunohorizons; 2021 Mar; 5(3):135-146. PubMed ID: 33685907
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Opposite Roles of RNase and Kinase Activities of Inositol-Requiring Enzyme 1 (IRE1) on HSV-1 Replication.
    Su A; Wang H; Li Y; Wang X; Chen D; Wu Z
    Viruses; 2017 Aug; 9(9):. PubMed ID: 28832521
    [TBL] [Abstract][Full Text] [Related]  

  • 7. IRE1-XBP1 pathway regulates oxidative proinsulin folding in pancreatic β cells.
    Tsuchiya Y; Saito M; Kadokura H; Miyazaki JI; Tashiro F; Imagawa Y; Iwawaki T; Kohno K
    J Cell Biol; 2018 Apr; 217(4):1287-1301. PubMed ID: 29507125
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Triazoloacridone C-1305 impairs XBP1 splicing by acting as a potential IRE1α endoribonuclease inhibitor.
    Bartoszewska S; Króliczewski J; Crossman DK; Pogorzelska A; Bagiński M; Collawn JF; Bartoszewski R
    Cell Mol Biol Lett; 2021 Mar; 26(1):11. PubMed ID: 33730996
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The IRE1α/XBP1s Pathway Is Essential for the Glucose Response and Protection of β Cells.
    Hassler JR; Scheuner DL; Wang S; Han J; Kodali VK; Li P; Nguyen J; George JS; Davis C; Wu SP; Bai Y; Sartor M; Cavalcoli J; Malhi H; Baudouin G; Zhang Y; Yates JR; Itkin-Ansari P; Volkmann N; Kaufman RJ
    PLoS Biol; 2015 Oct; 13(10):e1002277. PubMed ID: 26469762
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulation of IRE1α by the small molecule inhibitor 4μ8c in hepatoma cells.
    Stewart C; Estrada A; Kim P; Wang D; Wei Y; Gentile C; Pagliassotti M
    Endoplasmic Reticulum Stress Dis; 2017 Apr; 4(1):1-10. PubMed ID: 29098149
    [TBL] [Abstract][Full Text] [Related]  

  • 11. [Pathogenic Mechanism of Diabetes Development Due to Dysfunction of Unfolded Protein Response].
    Tsuchiya Y; Saito M; Kohno K
    Yakugaku Zasshi; 2016; 136(6):817-25. PubMed ID: 27252061
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dual and opposing roles of the unfolded protein response regulated by IRE1alpha and XBP1 in proinsulin processing and insulin secretion.
    Lee AH; Heidtman K; Hotamisligil GS; Glimcher LH
    Proc Natl Acad Sci U S A; 2011 May; 108(21):8885-90. PubMed ID: 21555585
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of IRE1α-driven pro-survival pathways is a promising therapeutic application in acute myeloid leukemia.
    Sun H; Lin DC; Guo X; Kharabi Masouleh B; Gery S; Cao Q; Alkan S; Ikezoe T; Akiba C; Paquette R; Chien W; Müller-Tidow C; Jing Y; Agelopoulos K; Müschen M; Koeffler HP
    Oncotarget; 2016 Apr; 7(14):18736-49. PubMed ID: 26934650
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis.
    Zhang K; Wong HN; Song B; Miller CN; Scheuner D; Kaufman RJ
    J Clin Invest; 2005 Feb; 115(2):268-81. PubMed ID: 15690081
    [TBL] [Abstract][Full Text] [Related]  

  • 15. XBP1: A Pivotal Transcriptional Regulator of Glucose and Lipid Metabolism.
    Piperi C; Adamopoulos C; Papavassiliou AG
    Trends Endocrinol Metab; 2016 Mar; 27(3):119-122. PubMed ID: 26803729
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Allosteric inhibition of the IRE1α RNase preserves cell viability and function during endoplasmic reticulum stress.
    Ghosh R; Wang L; Wang ES; Perera BG; Igbaria A; Morita S; Prado K; Thamsen M; Caswell D; Macias H; Weiberth KF; Gliedt MJ; Alavi MV; Hari SB; Mitra AK; Bhhatarai B; Schürer SC; Snapp EL; Gould DB; German MS; Backes BJ; Maly DJ; Oakes SA; Papa FR
    Cell; 2014 Jul; 158(3):534-48. PubMed ID: 25018104
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cdc37/Hsp90 protein-mediated regulation of IRE1α protein activity in endoplasmic reticulum stress response and insulin synthesis in INS-1 cells.
    Ota A; Wang Y
    J Biol Chem; 2012 Feb; 287(9):6266-74. PubMed ID: 22199355
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Knockdown of IRE1α inhibits colonic tumorigenesis through decreasing β-catenin and IRE1α targeting suppresses colon cancer cells.
    Li XX; Zhang HS; Xu YM; Zhang RJ; Chen Y; Fan L; Qin YQ; Liu Y; Li M; Fang J
    Oncogene; 2017 Nov; 36(48):6738-6746. PubMed ID: 28825721
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The inositol-requiring enzyme 1 (IRE1α) RNAse inhibitor, 4µ8C, is also a potent cellular antioxidant.
    Chan SMH; Lowe MP; Bernard A; Miller AA; Herbert TP
    Biochem J; 2018 Mar; 475(5):923-929. PubMed ID: 29463644
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A Human IRE1 Inhibitor Blocks the Unfolded Protein Response in the Pathogenic Fungus Aspergillus fumigatus and Suggests Noncanonical Functions within the Pathway.
    Guirao-Abad JP; Weichert M; Albee A; Deck K; Askew DS
    mSphere; 2020 Oct; 5(5):. PubMed ID: 33087521
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.