BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

331 related articles for article (PubMed ID: 28321119)

  • 41. Fragment analysis represents a suitable approach for the detection of hotspot c.7541_7542delCT NOTCH1 mutation in chronic lymphocytic leukemia.
    Vavrova E; Kantorova B; Vonkova B; Kabathova J; Skuhrova-Francova H; Diviskova E; Letocha O; Kotaskova J; Brychtova Y; Doubek M; Mayer J; Pospisilova S
    Leuk Res; 2017 Sep; 60():145-150. PubMed ID: 28837890
    [TBL] [Abstract][Full Text] [Related]  

  • 42. New insights into Notch1 regulation of the PI3K-AKT-mTOR1 signaling axis: targeted therapy of γ-secretase inhibitor resistant T-cell acute lymphoblastic leukemia.
    Hales EC; Taub JW; Matherly LH
    Cell Signal; 2014 Jan; 26(1):149-61. PubMed ID: 24140475
    [TBL] [Abstract][Full Text] [Related]  

  • 43. 14q deletions are associated with trisomy 12, NOTCH1 mutations and unmutated IGHV genes in chronic lymphocytic leukemia and small lymphocytic lymphoma.
    Cosson A; Chapiro E; Belhouachi N; Cung HA; Keren B; Damm F; Algrin C; Lefebvre C; Fert-Ferrer S; Luquet I; Gachard N; Mugneret F; Terre C; Collonge-Rame MA; Michaux L; Rafdord-Weiss I; Talmant P; Veronese L; Nadal N; Struski S; Barin C; Helias C; Lafage M; Lippert E; Auger N; Eclache V; Roos-Weil D; Leblond V; Settegrana C; Maloum K; Davi F; Merle-Beral H; Lesty C; Nguyen-Khac F;
    Genes Chromosomes Cancer; 2014 Aug; 53(8):657-66. PubMed ID: 24729385
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Notch signaling promotes disease initiation and progression in murine chronic lymphocytic leukemia.
    Tardivon D; Antoszewski M; Zangger N; Nkosi M; Sordet-Dessimoz J; Hendriks R; Koch U; Radtke F
    Blood; 2021 Jun; 137(22):3079-3092. PubMed ID: 33512383
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Detection of NOTCH1 c.7541_7542delCT mutation in chronic lymphocytic leukemia using conventional and real-time polymerase chain reaction.
    Bilous NI; Abramenko IV; Chumak AA; Dyagil IS; Martіna ZV
    Exp Oncol; 2016 Jun; 38(2):112-6. PubMed ID: 27356580
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Constitutive phosphorylation of the active Notch1 intracellular domain in chronic lymphocytic leukemia cells with NOTCH1 mutation.
    De Falco F; Sabatini R; Falzetti F; Di Ianni M; Sportoletti P; Baldoni S; Del Papa B; Screpanti I; Marconi P; Rosati E
    Leukemia; 2015 Apr; 29(4):994-8. PubMed ID: 25425197
    [No Abstract]   [Full Text] [Related]  

  • 47. Proliferation centres of chronic lymphocytic leukaemia/small lymphocytic lymphoma have enhanced expression of MYC protein, which does not result from rearrangement or gain of the MYC gene.
    Gibson SE; Leeman-Neill RJ; Jain S; Piao W; Cieply KM; Swerdlow SH
    Br J Haematol; 2016 Oct; 175(1):173-5. PubMed ID: 26568397
    [No Abstract]   [Full Text] [Related]  

  • 48. NOTCH1 mutations identify a chronic lymphocytic leukemia patient subset with worse prognosis in the setting of a rituximab-based induction and consolidation treatment.
    Bo MD; Del Principe MI; Pozzo F; Ragusa D; Bulian P; Rossi D; Capelli G; Rossi FM; Niscola P; Buccisano F; Bomben R; Zucchetto A; Maurillo L; de Fabritiis P; Amadori S; Gaidano G; Gattei V; Del Poeta G
    Ann Hematol; 2014 Oct; 93(10):1765-74. PubMed ID: 24923451
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Ultrasensitive Detection of NOTCH1 c.7544_7545delCT Mutations in Chronic Lymphocytic Leukemia by Droplet Digital PCR Reveals High Frequency of Subclonal Mutations and Predicts Clinical Outcome in Cases with Trisomy 12.
    Hoofd C; Huang SJ; Gusscott S; Lam S; Wong R; Johnston A; Ben-Neriah S; Steidl C; Scott DW; Bruyere H; Gillan TL; Toze CL; Gerrie AS; Weng AP
    J Mol Diagn; 2020 Apr; 22(4):571-578. PubMed ID: 32036086
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Resistance to CD95-mediated apoptosis of CD40-activated chronic lymphocytic leukemia B cells is not related to lack of DISC molecules expression.
    de Totero D; Montera M; Rosso O; Clavio M; Balleari E; Foa R; Gobbi M
    Hematol J; 2004; 5(2):152-60. PubMed ID: 15048066
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Interactions between bone marrow stromal microenvironment and B-chronic lymphocytic leukemia cells: any role for Notch, Wnt and Hh signaling pathways?
    Seke Etet PF; Vecchio L; Nwabo Kamdje AH
    Cell Signal; 2012 Jul; 24(7):1433-43. PubMed ID: 22446006
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Chronic lymphocytic leukemia: a clinical and molecular heterogenous disease.
    Rodríguez-Vicente AE; Díaz MG; Hernández-Rivas JM
    Cancer Genet; 2013 Mar; 206(3):49-62. PubMed ID: 23531595
    [TBL] [Abstract][Full Text] [Related]  

  • 53. The SIRT1/TP53 axis is activated upon B-cell receptor triggering via miR-132 up-regulation in chronic lymphocytic leukemia cells.
    Dal Bo M; D'Agaro T; Gobessi S; Zucchetto A; Dereani S; Rossi D; Zaja F; Pozzato G; Di Raimondo F; Gaidano G; Laurenti L; Del Poeta G; Efremov DG; Gattei V; Bomben R
    Oncotarget; 2015 Aug; 6(22):19102-17. PubMed ID: 26036258
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Activation of
    Biran A; Yin S; Kretzmer H; Ten Hacken E; Parvin S; Lucas F; Uduman M; Gutierrez C; Dangle N; Billington L; Regis FF; Rassenti LZ; Mohammad A; Hoffmann GB; Stevenson K; Zheng M; Witten E; Fernandes SM; Tausch E; Sun C; Stilgenbauer S; Brown JR; Kipps TJ; Aster JC; Gnirke A; Neuberg DS; Letai A; Wang L; Carrasco RD; Meissner A; Wu CJ
    Cancer Res; 2021 Dec; 81(24):6117-6130. PubMed ID: 34686499
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Novel prognostic gene mutations identified in chronic lymphocytic leukemia and their impact on clinical practice.
    Campregher PV; Hamerschlak N
    Clin Lymphoma Myeloma Leuk; 2014 Aug; 14(4):271-6. PubMed ID: 24548608
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Genomic alterations in high-risk chronic lymphocytic leukemia frequently affect cell cycle key regulators and NOTCH1-regulated transcription.
    Edelmann J; Holzmann K; Tausch E; Saunderson EA; Jebaraj BMC; Steinbrecher D; Dolnik A; Blätte TJ; Landau DA; Saub J; Estenfelder S; Ibach S; Cymbalista F; Leblond V; Delmer A; Bahlo J; Robrecht S; Fischer K; Goede V; Bullinger L; Wu CJ; Mertens D; Ficz G; Gribben JG; Hallek M; Döhner H; Stilgenbauer S
    Haematologica; 2020 May; 105(5):1379-1390. PubMed ID: 31467127
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Notch in Leukemia.
    McCarter AC; Wang Q; Chiang M
    Adv Exp Med Biol; 2018; 1066():355-394. PubMed ID: 30030836
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation.
    Fabbri G; Rasi S; Rossi D; Trifonov V; Khiabanian H; Ma J; Grunn A; Fangazio M; Capello D; Monti S; Cresta S; Gargiulo E; Forconi F; Guarini A; Arcaini L; Paulli M; Laurenti L; Larocca LM; Marasca R; Gattei V; Oscier D; Bertoni F; Mullighan CG; Foá R; Pasqualucci L; Rabadan R; Dalla-Favera R; Gaidano G
    J Exp Med; 2011 Jul; 208(7):1389-401. PubMed ID: 21670202
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Next-generation sequencing in chronic lymphocytic leukemia.
    Villamor N; López-Guillermo A; López-Otín C; Campo E
    Semin Hematol; 2013 Oct; 50(4):286-95. PubMed ID: 24246696
    [TBL] [Abstract][Full Text] [Related]  

  • 60. GSK3β is a critical, druggable component of the network regulating the active NOTCH1 protein and cell viability in CLL.
    De Falco F; Rompietti C; Sorcini D; Esposito A; Scialdone A; Baldoni S; Del Papa B; Adamo FM; Silva Barcelos EC; Dorillo E; Stella A; Di Ianni M; Screpanti I; Sportoletti P; Rosati E
    Cell Death Dis; 2022 Sep; 13(9):755. PubMed ID: 36050315
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 17.