BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1396 related articles for article (PubMed ID: 28321286)

  • 1. CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in cerebral organoids derived from iPS cells.
    Wang P; Mokhtari R; Pedrosa E; Kirschenbaum M; Bayrak C; Zheng D; Lachman HM
    Mol Autism; 2017; 8():11. PubMed ID: 28321286
    [TBL] [Abstract][Full Text] [Related]  

  • 2. CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in neurodevelopment.
    Wang P; Lin M; Pedrosa E; Hrabovsky A; Zhang Z; Guo W; Lachman HM; Zheng D
    Mol Autism; 2015; 6():55. PubMed ID: 26491539
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CHD8 regulates neurodevelopmental pathways associated with autism spectrum disorder in neural progenitors.
    Sugathan A; Biagioli M; Golzio C; Erdin S; Blumenthal I; Manavalan P; Ragavendran A; Brand H; Lucente D; Miles J; Sheridan SD; Stortchevoi A; Kellis M; Haggarty SJ; Katsanis N; Gusella JF; Talkowski ME
    Proc Natl Acad Sci U S A; 2014 Oct; 111(42):E4468-77. PubMed ID: 25294932
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Heterozygous deletion of the autism-associated gene CHD8 impairs synaptic function through widespread changes in gene expression and chromatin compaction.
    Shi X; Lu C; Corman A; Nikish A; Zhou Y; Platt RJ; Iossifov I; Zhang F; Pan JQ; Sanjana NE
    Am J Hum Genet; 2023 Oct; 110(10):1750-1768. PubMed ID: 37802044
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Functional DNA methylation signatures for autism spectrum disorder genomic risk loci: 16p11.2 deletions and CHD8 variants.
    Siu MT; Butcher DT; Turinsky AL; Cytrynbaum C; Stavropoulos DJ; Walker S; Caluseriu O; Carter M; Lou Y; Nicolson R; Georgiades S; Szatmari P; Anagnostou E; Scherer SW; Choufani S; Brudno M; Weksberg R
    Clin Epigenetics; 2019 Jul; 11(1):103. PubMed ID: 31311581
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Gene-Environment Interactions in Developmental Neurotoxicity: a Case Study of Synergy between Chlorpyrifos and CHD8 Knockout in Human BrainSpheres.
    Modafferi S; Zhong X; Kleensang A; Murata Y; Fagiani F; Pamies D; Hogberg HT; Calabrese V; Lachman H; Hartung T; Smirnova L
    Environ Health Perspect; 2021 Jul; 129(7):77001. PubMed ID: 34259569
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Modeling the neuropsychiatric manifestations of Lowe syndrome using induced pluripotent stem cells: defective F-actin polymerization and WAVE-1 expression in neuronal cells.
    Barnes J; Salas F; Mokhtari R; Dolstra H; Pedrosa E; Lachman HM
    Mol Autism; 2018; 9():44. PubMed ID: 30147856
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The autism-associated gene chromodomain helicase DNA-binding protein 8 (CHD8) regulates noncoding RNAs and autism-related genes.
    Wilkinson B; Grepo N; Thompson BL; Kim J; Wang K; Evgrafov OV; Lu W; Knowles JA; Campbell DB
    Transl Psychiatry; 2015 May; 5(5):e568. PubMed ID: 25989142
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Single-Cell Transcriptomics Supports a Role of
    Hoffmann A; Spengler D
    Int J Mol Sci; 2021 Mar; 22(6):. PubMed ID: 33806835
    [TBL] [Abstract][Full Text] [Related]  

  • 10. TSC patient-derived isogenic neural progenitor cells reveal altered early neurodevelopmental phenotypes and rapamycin-induced MNK-eIF4E signaling.
    Martin P; Wagh V; Reis SA; Erdin S; Beauchamp RL; Shaikh G; Talkowski M; Thiele E; Sheridan SD; Haggarty SJ; Ramesh V
    Mol Autism; 2020; 11(1):2. PubMed ID: 31921404
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The autism-associated chromatin modifier CHD8 regulates other autism risk genes during human neurodevelopment.
    Cotney J; Muhle RA; Sanders SJ; Liu L; Willsey AJ; Niu W; Liu W; Klei L; Lei J; Yin J; Reilly SK; Tebbenkamp AT; Bichsel C; Pletikos M; Sestan N; Roeder K; State MW; Devlin B; Noonan JP
    Nat Commun; 2015 Mar; 6():6404. PubMed ID: 25752243
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Autism-associated CHD8 keeps proliferation of human neural progenitors in check by lengthening the G1 phase of the cell cycle.
    Coakley-Youngs E; Ranatunga M; Richardson S; Getti G; Shorter S; Fivaz M
    Biol Open; 2022 Sep; 11(9):. PubMed ID: 36222238
    [TBL] [Abstract][Full Text] [Related]  

  • 13. ZNF804A Transcriptional Networks in Differentiating Neurons Derived from Induced Pluripotent Stem Cells of Human Origin.
    Chen J; Lin M; Hrabovsky A; Pedrosa E; Dean J; Jain S; Zheng D; Lachman HM
    PLoS One; 2015; 10(4):e0124597. PubMed ID: 25905630
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Autism spectrum disorder early in development associated with CHD8 mutations among two Chinese children.
    Wang J; Liu J; Gao Y; Wang K; Jiang K
    BMC Pediatr; 2018 Oct; 18(1):338. PubMed ID: 30376831
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Gene Regulation Analysis Reveals Perturbations of Autism Spectrum Disorder during Neural System Development.
    Li D; Xu J; Yang MQ
    Genes (Basel); 2021 Nov; 12(12):. PubMed ID: 34946850
    [TBL] [Abstract][Full Text] [Related]  

  • 16. CHD8 dosage regulates transcription in pluripotency and early murine neural differentiation.
    Sood S; Weber CM; Hodges HC; Krokhotin A; Shalizi A; Crabtree GR
    Proc Natl Acad Sci U S A; 2020 Sep; 117(36):22331-22340. PubMed ID: 32839322
    [TBL] [Abstract][Full Text] [Related]  

  • 17. CHD8 intragenic deletion associated with autism spectrum disorder.
    Stolerman ES; Smith B; Chaubey A; Jones JR
    Eur J Med Genet; 2016 Apr; 59(4):189-94. PubMed ID: 26921529
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Common CHD8 Genomic Targets Contrast With Model-Specific Transcriptional Impacts of
    Wade AA; Lim K; Catta-Preta R; Nord AS
    Front Mol Neurosci; 2018; 11():481. PubMed ID: 30692911
    [TBL] [Abstract][Full Text] [Related]  

  • 19. CHD8 haploinsufficiency results in autistic-like phenotypes in mice.
    Katayama Y; Nishiyama M; Shoji H; Ohkawa Y; Kawamura A; Sato T; Suyama M; Takumi T; Miyakawa T; Nakayama KI
    Nature; 2016 Sep; 537(7622):675-679. PubMed ID: 27602517
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Integrative transcriptome network analysis of iPSC-derived neurons from schizophrenia and schizoaffective disorder patients with 22q11.2 deletion.
    Lin M; Pedrosa E; Hrabovsky A; Chen J; Puliafito BR; Gilbert SR; Zheng D; Lachman HM
    BMC Syst Biol; 2016 Nov; 10(1):105. PubMed ID: 27846841
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 70.