These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
22. Stromal platelet-derived growth factor receptor α (PDGFRα) provides a therapeutic target independent of tumor cell PDGFRα expression in lung cancer xenografts. Gerber DE; Gupta P; Dellinger MT; Toombs JE; Peyton M; Duignan I; Malaby J; Bailey T; Burns C; Brekken RA; Loizos N Mol Cancer Ther; 2012 Nov; 11(11):2473-82. PubMed ID: 22933705 [TBL] [Abstract][Full Text] [Related]
23. Abnormal platelet-derived growth factor signaling accounting for lung hypoplasia in experimental congenital diaphragmatic hernia. Dingemann J; Doi T; Ruttenstock E; Puri P J Pediatr Surg; 2010 Oct; 45(10):1989-94. PubMed ID: 20920717 [TBL] [Abstract][Full Text] [Related]
24. Platelet-derived growth factor-D modulates extracellular matrix homeostasis and remodeling through TIMP-1 induction and attenuation of MMP-2 and MMP-9 gelatinase activities. Borkham-Kamphorst E; Alexi P; Tihaa L; Haas U; Weiskirchen R Biochem Biophys Res Commun; 2015 Feb; 457(3):307-13. PubMed ID: 25576870 [TBL] [Abstract][Full Text] [Related]
25. Platelet-derived growth factor-A and sonic hedgehog signaling direct lung fibroblast precursors during alveolar septal formation. McGowan SE; McCoy DM Am J Physiol Lung Cell Mol Physiol; 2013 Aug; 305(3):L229-39. PubMed ID: 23748534 [TBL] [Abstract][Full Text] [Related]
26. Analysis of mice lacking the heparin-binding splice isoform of platelet-derived growth factor A. Andrae J; Ehrencrona H; Gallini R; Lal M; Ding H; Betsholtz C Mol Cell Biol; 2013 Oct; 33(20):4030-40. PubMed ID: 23938297 [TBL] [Abstract][Full Text] [Related]
27. Bone Morphogenic Protein 4-Smad-Induced Upregulation of Platelet-Derived Growth Factor AA Impairs Endothelial Function. Hu W; Zhang Y; Wang L; Lau CW; Xu J; Luo JY; Gou L; Yao X; Chen ZY; Ma RC; Tian XY; Huang Y Arterioscler Thromb Vasc Biol; 2016 Mar; 36(3):553-60. PubMed ID: 26769046 [TBL] [Abstract][Full Text] [Related]
28. Insight into the physiological functions of PDGF through genetic studies in mice. Betsholtz C Cytokine Growth Factor Rev; 2004 Aug; 15(4):215-28. PubMed ID: 15207813 [TBL] [Abstract][Full Text] [Related]
29. Characterization of platelet-derived growth factor-A expression in mouse tissues using a lacZ knock-in approach. Andrae J; Gouveia L; He L; Betsholtz C PLoS One; 2014; 9(8):e105477. PubMed ID: 25166724 [TBL] [Abstract][Full Text] [Related]
30. Platelet-derived growth factor receptor-alpha-expressing cells localize to the alveolar entry ring and have characteristics of myofibroblasts during pulmonary alveolar septal formation. McGowan SE; Grossmann RE; Kimani PW; Holmes AJ Anat Rec (Hoboken); 2008 Dec; 291(12):1649-61. PubMed ID: 18833569 [TBL] [Abstract][Full Text] [Related]
31. Combined anti-PDGFRalpha and PDGFRbeta targeting in non-small cell lung cancer. Reinmuth N; Liersch R; Raedel M; Fehrmann F; Fehrmann N; Bayer M; Schwoeppe C; Kessler T; Berdel W; Thomas M; Mesters RM Int J Cancer; 2009 Apr; 124(7):1535-44. PubMed ID: 19115205 [TBL] [Abstract][Full Text] [Related]
33. Alveogenesis failure in PDGF-A-deficient mice is coupled to lack of distal spreading of alveolar smooth muscle cell progenitors during lung development. Lindahl P; Karlsson L; Hellström M; Gebre-Medhin S; Willetts K; Heath JK; Betsholtz C Development; 1997 Oct; 124(20):3943-53. PubMed ID: 9374392 [TBL] [Abstract][Full Text] [Related]
34. Tumor-driven paracrine platelet-derived growth factor receptor alpha signaling is a key determinant of stromal cell recruitment in a model of human lung carcinoma. Tejada ML; Yu L; Dong J; Jung K; Meng G; Peale FV; Frantz GD; Hall L; Liang X; Gerber HP; Ferrara N Clin Cancer Res; 2006 May; 12(9):2676-88. PubMed ID: 16675559 [TBL] [Abstract][Full Text] [Related]
35. A Novel Pharmacodynamic Biomarker and Mechanistic Modeling Facilitate the Development of Tovetumab, a Monoclonal Antibody Directed Against Platelet-Derived Growth Factor Receptor Alpha, for Cancer Therapy. Liang M; Wang B; Schneider A; Vainshtein I; Roskos L AAPS J; 2020 Nov; 23(1):4. PubMed ID: 33210183 [TBL] [Abstract][Full Text] [Related]
36. PDGF-A signaling is a critical event in lung alveolar myofibroblast development and alveogenesis. Boström H; Willetts K; Pekny M; Levéen P; Lindahl P; Hedstrand H; Pekna M; Hellström M; Gebre-Medhin S; Schalling M; Nilsson M; Kurland S; Törnell J; Heath JK; Betsholtz C Cell; 1996 Jun; 85(6):863-73. PubMed ID: 8681381 [TBL] [Abstract][Full Text] [Related]
37. Platelet-derived growth factor-C (PDGF-C) induces anti-apoptotic effects on macrophages through Akt and Bad phosphorylation. Son D; Na YR; Hwang ES; Seok SH J Biol Chem; 2014 Feb; 289(9):6225-35. PubMed ID: 24421315 [TBL] [Abstract][Full Text] [Related]
38. Platelet-derived growth factor C is upregulated in human uterine fibroids and regulates uterine smooth muscle cell growth. Suo G; Jiang Y; Cowan B; Wang JY Biol Reprod; 2009 Oct; 81(4):749-58. PubMed ID: 19553600 [TBL] [Abstract][Full Text] [Related]
39. Expression and function of PDGF-C in development and stem cells. Tian Y; Zhan Y; Jiang Q; Lu W; Li X Open Biol; 2021 Dec; 11(12):210268. PubMed ID: 34847773 [TBL] [Abstract][Full Text] [Related]
40. PDGF C is a selective alpha platelet-derived growth factor receptor agonist that is highly expressed in platelet alpha granules and vascular smooth muscle. Fang L; Yan Y; Komuves LG; Yonkovich S; Sullivan CM; Stringer B; Galbraith S; Lokker NA; Hwang SS; Nurden P; Phillips DR; Giese NA Arterioscler Thromb Vasc Biol; 2004 Apr; 24(4):787-92. PubMed ID: 15061151 [TBL] [Abstract][Full Text] [Related] [Previous] [Next] [New Search]