These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

296 related articles for article (PubMed ID: 28338621)

  • 1. Optimized 4,5-Diarylimidazoles as Potent/Selective Inhibitors of Protein Kinase CK1δ and Their Structural Relation to p38α MAPK.
    Halekotte J; Witt L; Ianes C; Krüger M; Bührmann M; Rauh D; Pichlo C; Brunstein E; Luxenburger A; Baumann U; Knippschild U; Bischof J; Peifer C
    Molecules; 2017 Mar; 22(4):. PubMed ID: 28338621
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 3,4-Diaryl-isoxazoles and -imidazoles as potent dual inhibitors of p38alpha mitogen activated protein kinase and casein kinase 1delta.
    Peifer C; Abadleh M; Bischof J; Hauser D; Schattel V; Hirner H; Knippschild U; Laufer S
    J Med Chem; 2009 Dec; 52(23):7618-30. PubMed ID: 19591487
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and structure-activity relationships of 4-fluorophenyl-imidazole p38α MAPK, CK1δ and JAK2 kinase inhibitors.
    Seerden JP; Leusink-Ionescu G; Woudenberg-Vrenken T; Dros B; Molema G; Kamps JA; Kellogg RM
    Bioorg Med Chem Lett; 2014 Aug; 24(15):3412-8. PubMed ID: 24930833
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of Inhibitor of Wnt Production 2 (IWP-2) and Related Compounds As Selective ATP-Competitive Inhibitors of Casein Kinase 1 (CK1) δ/ε.
    García-Reyes B; Witt L; Jansen B; Karasu E; Gehring T; Leban J; Henne-Bruns D; Pichlo C; Brunstein E; Baumann U; Wesseler F; Rathmer B; Schade D; Peifer C; Knippschild U
    J Med Chem; 2018 May; 61(9):4087-4102. PubMed ID: 29630366
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 2-Azo-, 2-diazocine-thiazols and 2-azo-imidazoles as photoswitchable kinase inhibitors: limitations and pitfalls of the photoswitchable inhibitor approach.
    Schehr M; Ianes C; Weisner J; Heintze L; Müller MP; Pichlo C; Charl J; Brunstein E; Ewert J; Lehr M; Baumann U; Rauh D; Knippschild U; Peifer C; Herges R
    Photochem Photobiol Sci; 2019 Jun; 18(6):1398-1407. PubMed ID: 30924488
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Difluoro-dioxolo-benzoimidazol-benzamides as potent inhibitors of CK1δ and ε with nanomolar inhibitory activity on cancer cell proliferation.
    Richter J; Bischof J; Zaja M; Kohlhof H; Othersen O; Vitt D; Alscher V; Pospiech I; García-Reyes B; Berg S; Leban J; Knippschild U
    J Med Chem; 2014 Oct; 57(19):7933-46. PubMed ID: 25191940
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural basis for the interaction between casein kinase 1 delta and a potent and selective inhibitor.
    Long A; Zhao H; Huang X
    J Med Chem; 2012 Jan; 55(2):956-60. PubMed ID: 22168824
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 7-Amino-[1,2,4]triazolo[1,5-a][1,3,5]triazines as CK1δ inhibitors: Exploring substitutions at the 2 and 5-positions.
    Grieco I; Bassani D; Trevisan L; Salmaso V; Cescon E; Prencipe F; Da Ros T; Martinez-Gonzalez L; Martinez A; Spalluto G; Moro S; Federico S
    Bioorg Chem; 2024 Oct; 151():107659. PubMed ID: 39059072
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure-Based Development of Isoform-Selective Inhibitors of Casein Kinase 1ε vs Casein Kinase 1δ.
    Choi JY; Noguchi Y; Alburger JM; Bayle S; Chung E; Grant W; Chaikuad A; Knapp S; Duckett DR; Roush WR
    J Med Chem; 2023 Jun; 66(11):7162-7178. PubMed ID: 37204207
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ligand-protein interactions of selective casein kinase 1δ inhibitors.
    Mente S; Arnold E; Butler T; Chakrapani S; Chandrasekaran R; Cherry K; DiRico K; Doran A; Fisher K; Galatsis P; Green M; Hayward M; Humphrey J; Knafels J; Li J; Liu S; Marconi M; McDonald S; Ohren J; Paradis V; Sneed B; Walton K; Wager T
    J Med Chem; 2013 Sep; 56(17):6819-28. PubMed ID: 23919824
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Newly Developed CK1-Specific Inhibitors Show Specifically Stronger Effects on CK1 Mutants and Colon Cancer Cell Lines.
    Liu C; Witt L; Ianes C; Bischof J; Bammert MT; Baier J; Kirschner S; Henne-Bruns D; Xu P; Kornmann M; Peifer C; Knippschild U
    Int J Mol Sci; 2019 Dec; 20(24):. PubMed ID: 31817920
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Implications for selectivity of 3,4-diarylquinolinones as p38alphaMAP kinase inhibitors.
    Peifer C; Urich R; Schattel V; Abadleh M; Röttig M; Kohlbacher O; Laufer S
    Bioorg Med Chem Lett; 2008 Feb; 18(4):1431-5. PubMed ID: 18207396
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Developing novel classes of protein kinase CK1δ inhibitors by fusing [1,2,4]triazole with different bicyclic heteroaromatic systems.
    Grieco I; Bissaro M; Tiz DB; Perez DI; Perez C; Martinez A; Redenti S; Mariotto E; Bortolozzi R; Viola G; Cozza G; Spalluto G; Moro S; Federico S
    Eur J Med Chem; 2021 Apr; 216():113331. PubMed ID: 33721670
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 2-Benzamido-N-(1H-benzo[d]imidazol-2-yl)thiazole-4-carboxamide derivatives as potent inhibitors of CK1δ/ε.
    Bischof J; Leban J; Zaja M; Grothey A; Radunsky B; Othersen O; Strobl S; Vitt D; Knippschild U
    Amino Acids; 2012 Oct; 43(4):1577-91. PubMed ID: 22331384
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Recent Advances in the Development of Casein Kinase 1 Inhibitors.
    Li SS; Dong YH; Liu ZP
    Curr Med Chem; 2021; 28(8):1585-1604. PubMed ID: 32660395
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tetra-substituted pyridinylimidazoles as dual inhibitors of p38α mitogen-activated protein kinase and c-Jun N-terminal kinase 3 for potential treatment of neurodegenerative diseases.
    Muth F; Günther M; Bauer SM; Döring E; Fischer S; Maier J; Drückes P; Köppler J; Trappe J; Rothbauer U; Koch P; Laufer SA
    J Med Chem; 2015 Jan; 58(1):443-56. PubMed ID: 25475894
    [TBL] [Abstract][Full Text] [Related]  

  • 17. CK1δ/ε kinases regulate TDP-43 phosphorylation and are therapeutic targets for ALS-related TDP-43 hyperphosphorylation.
    Ko VI; Ong K; Cleveland DW; Yu H; Ravits JM
    Neurobiol Dis; 2024 Jun; 196():106516. PubMed ID: 38677657
    [TBL] [Abstract][Full Text] [Related]  

  • 18. C5-Iminosugar modification of casein kinase 1δ lead 3-(4-fluorophenyl)-5-isopropyl-4-(pyridin-4-yl)isoxazole promotes enhanced inhibitor affinity and selectivity.
    von Drathen T; Ure EM; Kirschner S; Roth A; Meier L; Woolhouse AD; Cameron SA; Knippschild U; Peifer C; Luxenburger A
    Arch Pharm (Weinheim); 2022 May; 355(5):e2100497. PubMed ID: 35174898
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A Computational Workflow for the Identification of Novel Fragments Acting as Inhibitors of the Activity of Protein Kinase CK1δ.
    Bolcato G; Cescon E; Pavan M; Bissaro M; Bassani D; Federico S; Spalluto G; Sturlese M; Moro S
    Int J Mol Sci; 2021 Sep; 22(18):. PubMed ID: 34575906
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural basis for the potent and selective inhibition of casein kinase 1 epsilon.
    Long AM; Zhao H; Huang X
    J Med Chem; 2012 Nov; 55(22):10307-11. PubMed ID: 23106386
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.