These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
465 related articles for article (PubMed ID: 28341788)
1. Discovery and Pharmacological Characterization of JNJ-42756493 (Erdafitinib), a Functionally Selective Small-Molecule FGFR Family Inhibitor. Perera TPS; Jovcheva E; Mevellec L; Vialard J; De Lange D; Verhulst T; Paulussen C; Van De Ven K; King P; Freyne E; Rees DC; Squires M; Saxty G; Page M; Murray CW; Gilissen R; Ward G; Thompson NT; Newell DR; Cheng N; Xie L; Yang J; Platero SJ; Karkera JD; Moy C; Angibaud P; Laquerre S; Lorenzi MV Mol Cancer Ther; 2017 Jun; 16(6):1010-1020. PubMed ID: 28341788 [TBL] [Abstract][Full Text] [Related]
2. Oncogenic Characterization and Pharmacologic Sensitivity of Activating Fibroblast Growth Factor Receptor (FGFR) Genetic Alterations to the Selective FGFR Inhibitor Erdafitinib. Karkera JD; Cardona GM; Bell K; Gaffney D; Portale JC; Santiago-Walker A; Moy CH; King P; Sharp M; Bahleda R; Luo FR; Alvarez JD; Lorenzi MV; Platero SJ Mol Cancer Ther; 2017 Aug; 16(8):1717-1726. PubMed ID: 28416604 [TBL] [Abstract][Full Text] [Related]
3. Multicenter Phase I Study of Erdafitinib (JNJ-42756493), Oral Pan-Fibroblast Growth Factor Receptor Inhibitor, in Patients with Advanced or Refractory Solid Tumors. Bahleda R; Italiano A; Hierro C; Mita A; Cervantes A; Chan N; Awad M; Calvo E; Moreno V; Govindan R; Spira A; Gonzalez M; Zhong B; Santiago-Walker A; Poggesi I; Parekh T; Xie H; Infante J; Tabernero J Clin Cancer Res; 2019 Aug; 25(16):4888-4897. PubMed ID: 31088831 [TBL] [Abstract][Full Text] [Related]
4. Phase I Dose-Escalation Study of JNJ-42756493, an Oral Pan-Fibroblast Growth Factor Receptor Inhibitor, in Patients With Advanced Solid Tumors. Tabernero J; Bahleda R; Dienstmann R; Infante JR; Mita A; Italiano A; Calvo E; Moreno V; Adamo B; Gazzah A; Zhong B; Platero SJ; Smit JW; Stuyckens K; Chatterjee-Kishore M; Rodon J; Peddareddigari V; Luo FR; Soria JC J Clin Oncol; 2015 Oct; 33(30):3401-8. PubMed ID: 26324363 [TBL] [Abstract][Full Text] [Related]
5. AZD4547: an orally bioavailable, potent, and selective inhibitor of the fibroblast growth factor receptor tyrosine kinase family. Gavine PR; Mooney L; Kilgour E; Thomas AP; Al-Kadhimi K; Beck S; Rooney C; Coleman T; Baker D; Mellor MJ; Brooks AN; Klinowska T Cancer Res; 2012 Apr; 72(8):2045-56. PubMed ID: 22369928 [TBL] [Abstract][Full Text] [Related]
6. The fibroblast growth factor receptor genetic status as a potential predictor of the sensitivity to CH5183284/Debio 1347, a novel selective FGFR inhibitor. Nakanishi Y; Akiyama N; Tsukaguchi T; Fujii T; Sakata K; Sase H; Isobe T; Morikami K; Shindoh H; Mio T; Ebiike H; Taka N; Aoki Y; Ishii N Mol Cancer Ther; 2014 Nov; 13(11):2547-58. PubMed ID: 25169980 [TBL] [Abstract][Full Text] [Related]
7. In vitro and in vivo evaluation of the radiosensitizing effect of a selective FGFR inhibitor (JNJ-42756493) for rectal cancer. Verstraete M; Debucquoy A; Gonnissen A; Dok R; Isebaert S; Devos E; McBride W; Haustermans K BMC Cancer; 2015 Dec; 15():946. PubMed ID: 26675289 [TBL] [Abstract][Full Text] [Related]
8. Futibatinib Is a Novel Irreversible FGFR 1-4 Inhibitor That Shows Selective Antitumor Activity against FGFR-Deregulated Tumors. Sootome H; Fujita H; Ito K; Ochiiwa H; Fujioka Y; Ito K; Miura A; Sagara T; Ito S; Ohsawa H; Otsuki S; Funabashi K; Yashiro M; Matsuo K; Yonekura K; Hirai H Cancer Res; 2020 Nov; 80(22):4986-4997. PubMed ID: 32973082 [TBL] [Abstract][Full Text] [Related]
9. Safety, pharmacokinetic, and pharmacodynamics of erdafitinib, a pan-fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitor, in patients with advanced or refractory solid tumors. Nishina T; Takahashi S; Iwasawa R; Noguchi H; Aoki M; Doi T Invest New Drugs; 2018 Jun; 36(3):424-434. PubMed ID: 28965185 [TBL] [Abstract][Full Text] [Related]
10. A Functional Genetic Screen Identifies the Phosphoinositide 3-kinase Pathway as a Determinant of Resistance to Fibroblast Growth Factor Receptor Inhibitors in FGFR Mutant Urothelial Cell Carcinoma. Wang L; Šuštić T; Leite de Oliveira R; Lieftink C; Halonen P; van de Ven M; Beijersbergen RL; van den Heuvel MM; Bernards R; van der Heijden MS Eur Urol; 2017 Jun; 71(6):858-862. PubMed ID: 28108151 [TBL] [Abstract][Full Text] [Related]
11. Erdafitinib: A novel therapy for FGFR-mutated urothelial cancer. Roubal K; Myint ZW; Kolesar JM Am J Health Syst Pharm; 2020 Feb; 77(5):346-351. PubMed ID: 32073123 [TBL] [Abstract][Full Text] [Related]
12. E7090, a Novel Selective Inhibitor of Fibroblast Growth Factor Receptors, Displays Potent Antitumor Activity and Prolongs Survival in Preclinical Models. Watanabe Miyano S; Yamamoto Y; Kodama K; Miyajima Y; Mikamoto M; Nakagawa T; Kuramochi H; Funasaka S; Nagao S; Sugi NH; Okamoto K; Minoshima Y; Nakatani Y; Karoji Y; Ohashi I; Yamane Y; Okada T; Matsushima T; Matsui J; Iwata M; Uenaka T; Tsuruoka A Mol Cancer Ther; 2016 Nov; 15(11):2630-2639. PubMed ID: 27535969 [TBL] [Abstract][Full Text] [Related]
13. Inhibition of the FGF/FGFR System Induces Apoptosis in Lung Cancer Cells via c-Myc Downregulation and Oxidative Stress. Giacomini A; Taranto S; Rezzola S; Matarazzo S; Grillo E; Bugatti M; Scotuzzi A; Guerra J; Di Trani M; Presta M; Ronca R Int J Mol Sci; 2020 Dec; 21(24):. PubMed ID: 33317057 [TBL] [Abstract][Full Text] [Related]
14. Identification of Pharmacodynamic Transcript Biomarkers in Response to FGFR Inhibition by AZD4547. Delpuech O; Rooney C; Mooney L; Baker D; Shaw R; Dymond M; Wang D; Zhang P; Cross S; Veldman-Jones M; Wilson J; Davies BR; Dry JR; Kilgour E; Smith PD Mol Cancer Ther; 2016 Nov; 15(11):2802-2813. PubMed ID: 27550940 [TBL] [Abstract][Full Text] [Related]
15. Erdafitinib for the treatment of urothelial cancer. Marandino L; Raggi D; Giannatempo P; Farè E; Necchi A Expert Rev Anticancer Ther; 2019 Oct; 19(10):835-846. PubMed ID: 31544541 [No Abstract] [Full Text] [Related]
17. Discovery of [5-Amino-1-(2-methyl-3H-benzimidazol-5-yl)pyrazol-4-yl]-(1H-indol-2-yl)methanone (CH5183284/Debio 1347), An Orally Available and Selective Fibroblast Growth Factor Receptor (FGFR) Inhibitor. Ebiike H; Taka N; Matsushita M; Ohmori M; Takami K; Hyohdoh I; Kohchi M; Hayase T; Nishii H; Morikami K; Nakanishi Y; Akiyama N; Shindoh H; Ishii N; Isobe T; Matsuoka H J Med Chem; 2016 Dec; 59(23):10586-10600. PubMed ID: 27933954 [TBL] [Abstract][Full Text] [Related]
18. Overview of the clinical use of erdafitinib as a treatment option for the metastatic urothelial carcinoma: where do we stand. D'Angelo A; Bagby S; Galli IC; Bortoletti C; Roviello G Expert Rev Clin Pharmacol; 2020 Oct; 13(10):1139-1146. PubMed ID: 32935605 [TBL] [Abstract][Full Text] [Related]
19. Effect of FGF/FGFR pathway blocking on lung adenocarcinoma and its cancer-associated fibroblasts. Hegab AE; Ozaki M; Kameyama N; Gao J; Kagawa S; Yasuda H; Soejima K; Yin Y; Guzy RD; Nakamura Y; Ornitz DM; Betsuyaku T J Pathol; 2019 Oct; 249(2):193-205. PubMed ID: 31090071 [TBL] [Abstract][Full Text] [Related]
20. A novel, selective inhibitor of fibroblast growth factor receptors that shows a potent broad spectrum of antitumor activity in several tumor xenograft models. Zhao G; Li WY; Chen D; Henry JR; Li HY; Chen Z; Zia-Ebrahimi M; Bloem L; Zhai Y; Huss K; Peng SB; McCann DJ Mol Cancer Ther; 2011 Nov; 10(11):2200-10. PubMed ID: 21900693 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]