487 related articles for article (PubMed ID: 28348409)
1. Inhibiting the system x
Liu DS; Duong CP; Haupt S; Montgomery KG; House CM; Azar WJ; Pearson HB; Fisher OM; Read M; Guerra GR; Haupt Y; Cullinane C; Wiman KG; Abrahmsen L; Phillips WA; Clemons NJ
Nat Commun; 2017 Mar; 8():14844. PubMed ID: 28348409
[TBL] [Abstract][Full Text] [Related]
2. Expression of xCT and activity of system xc(-) are regulated by NRF2 in human breast cancer cells in response to oxidative stress.
Habib E; Linher-Melville K; Lin HX; Singh G
Redox Biol; 2015 Aug; 5():33-42. PubMed ID: 25827424
[TBL] [Abstract][Full Text] [Related]
3. Inhibiting system x
Clemons NJ; Liu DS; Duong CP; Phillips WA
Mol Cell Oncol; 2017; 4(5):e1344757. PubMed ID: 29057306
[TBL] [Abstract][Full Text] [Related]
4. NRF2 Is a Major Target of ARF in p53-Independent Tumor Suppression.
Chen D; Tavana O; Chu B; Erber L; Chen Y; Baer R; Gu W
Mol Cell; 2017 Oct; 68(1):224-232.e4. PubMed ID: 28985506
[TBL] [Abstract][Full Text] [Related]
5. Mutant p53 Mediates Sensitivity to Cancer Treatment Agents in Oesophageal Adenocarcinoma Associated with MicroRNA and SLC7A11 Expression.
Eichelmann AK; Mayne GC; Chiam K; Due SL; Bastian I; Butz F; Wang T; Sykes PJ; Clemons NJ; Liu DS; Michael MZ; Karapetis CS; Hummel R; Watson DI; Hussey DJ
Int J Mol Sci; 2021 May; 22(11):. PubMed ID: 34074015
[No Abstract] [Full Text] [Related]
6. Transketolase regulates sensitivity to APR-246 in p53-null cells independently of oxidative stress modulation.
Milne JV; Zhang BZ; Fujihara KM; Dawar S; Phillips WA; Clemons NJ
Sci Rep; 2021 Feb; 11(1):4480. PubMed ID: 33627789
[TBL] [Abstract][Full Text] [Related]
7. The GTPase KRAS suppresses the p53 tumor suppressor by activating the NRF2-regulated antioxidant defense system in cancer cells.
Yang H; Xiang S; Kazi A; Sebti SM
J Biol Chem; 2020 Mar; 295(10):3055-3063. PubMed ID: 32001619
[TBL] [Abstract][Full Text] [Related]
8. Targeting the Vulnerability of Glutathione Metabolism in ARID1A-Deficient Cancers.
Ogiwara H; Takahashi K; Sasaki M; Kuroda T; Yoshida H; Watanabe R; Maruyama A; Makinoshima H; Chiwaki F; Sasaki H; Kato T; Okamoto A; Kohno T
Cancer Cell; 2019 Feb; 35(2):177-190.e8. PubMed ID: 30686770
[TBL] [Abstract][Full Text] [Related]
9. Cystine-glutamate antiporter xCT as a therapeutic target for cancer.
Liu L; Liu R; Liu Y; Li G; Chen Q; Liu X; Ma S
Cell Biochem Funct; 2021 Mar; 39(2):174-179. PubMed ID: 32749001
[TBL] [Abstract][Full Text] [Related]
10. SLC7A11 Is a Superior Determinant of APR-246 (Eprenetapopt) Response than
Fujihara KM; Corrales Benitez M; Cabalag CS; Zhang BZ; Ko HS; Liu DS; Simpson KJ; Haupt Y; Lipton L; Haupt S; Phillips WA; Clemons NJ
Mol Cancer Ther; 2021 Oct; 20(10):1858-1867. PubMed ID: 34315763
[TBL] [Abstract][Full Text] [Related]
11. Suppression of the SLC7A11/glutathione axis causes synthetic lethality in KRAS-mutant lung adenocarcinoma.
Hu K; Li K; Lv J; Feng J; Chen J; Wu H; Cheng F; Jiang W; Wang J; Pei H; Chiao PJ; Cai Z; Chen Y; Liu M; Pang X
J Clin Invest; 2020 Apr; 130(4):1752-1766. PubMed ID: 31874110
[TBL] [Abstract][Full Text] [Related]
12. Ferroptosis as a p53-mediated activity during tumour suppression.
Jiang L; Kon N; Li T; Wang SJ; Su T; Hibshoosh H; Baer R; Gu W
Nature; 2015 Apr; 520(7545):57-62. PubMed ID: 25799988
[TBL] [Abstract][Full Text] [Related]
13. Increased Expression of System xc- in Glioblastoma Confers an Altered Metabolic State and Temozolomide Resistance.
Polewski MD; Reveron-Thornton RF; Cherryholmes GA; Marinov GK; Cassady K; Aboody KS
Mol Cancer Res; 2016 Dec; 14(12):1229-1242. PubMed ID: 27658422
[TBL] [Abstract][Full Text] [Related]
14. Sigma 1 receptor regulates the oxidative stress response in primary retinal Müller glial cells via NRF2 signaling and system xc(-), the Na(+)-independent glutamate-cystine exchanger.
Wang J; Shanmugam A; Markand S; Zorrilla E; Ganapathy V; Smith SB
Free Radic Biol Med; 2015 Sep; 86():25-36. PubMed ID: 25920363
[TBL] [Abstract][Full Text] [Related]
15. Anti-leukaemic effects induced by APR-246 are dependent on induction of oxidative stress and the NFE2L2/HMOX1 axis that can be targeted by PI3K and mTOR inhibitors in acute myeloid leukaemia cells.
Ali D; Mohammad DK; Mujahed H; Jonson-Videsäter K; Nore B; Paul C; Lehmann S
Br J Haematol; 2016 Jul; 174(1):117-26. PubMed ID: 26991755
[TBL] [Abstract][Full Text] [Related]
16. Suppression of the SLC7A11/glutathione axis causes ferroptosis and apoptosis and alters the mitogen-activated protein kinase pathway in nasopharyngeal carcinoma.
Wang HH; Fan SQ; Zhan YT; Peng SP; Wang WY
Int J Biol Macromol; 2024 Jan; 254(Pt 3):127976. PubMed ID: 37951442
[TBL] [Abstract][Full Text] [Related]
17. ATF3 promotes erastin-induced ferroptosis by suppressing system Xc
Wang L; Liu Y; Du T; Yang H; Lei L; Guo M; Ding HF; Zhang J; Wang H; Chen X; Yan C
Cell Death Differ; 2020 Feb; 27(2):662-675. PubMed ID: 31273299
[TBL] [Abstract][Full Text] [Related]
18. Tumor-Associated Antigen xCT and Mutant-p53 as Molecular Targets for New Combinatorial Antitumor Strategies.
Magri J; Gasparetto A; Conti L; Calautti E; Cossu C; Ruiu R; Barutello G; Cavallo F
Cells; 2021 Jan; 10(1):. PubMed ID: 33430127
[TBL] [Abstract][Full Text] [Related]
19. Dynamic roles of p53-mediated metabolic activities in ROS-induced stress responses.
Jiang L; Hickman JH; Wang SJ; Gu W
Cell Cycle; 2015; 14(18):2881-5. PubMed ID: 26218928
[TBL] [Abstract][Full Text] [Related]
20. Mutant p53R273H attenuates the expression of phase 2 detoxifying enzymes and promotes the survival of cells with high levels of reactive oxygen species.
Kalo E; Kogan-Sakin I; Solomon H; Bar-Nathan E; Shay M; Shetzer Y; Dekel E; Goldfinger N; Buganim Y; Stambolsky P; Goldstein I; Madar S; Rotter V
J Cell Sci; 2012 Nov; 125(Pt 22):5578-86. PubMed ID: 22899716
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]