These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

195 related articles for article (PubMed ID: 28351483)

  • 1. Surface modified nano-lipid drug conjugates of positive allosteric modulators of M1 muscarinic acetylcholine receptor for the treatment of Alzheimer's disease.
    Chintamaneni PK; Krishnamurthy PT; Rao PV; Pindiprolu SS
    Med Hypotheses; 2017 Apr; 101():17-22. PubMed ID: 28351483
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Polysorbate-80 surface modified nano-stearylamine BQCA conjugate for the management of Alzheimer's disease.
    Chintamaneni PK; Krishnamurthy PT; Pindiprolu SKSS
    RSC Adv; 2021 Jan; 11(10):5325-5334. PubMed ID: 35423107
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Towards a high-affinity allosteric enhancer at muscarinic M1 receptors.
    Lazareno S; Popham A; Birdsall NJ
    J Mol Neurosci; 2002; 19(1-2):123-7. PubMed ID: 12212769
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The selective positive allosteric M1 muscarinic receptor modulator PQCA attenuates learning and memory deficits in the Tg2576 Alzheimer's disease mouse model.
    Puri V; Wang X; Vardigan JD; Kuduk SD; Uslaner JM
    Behav Brain Res; 2015; 287():96-9. PubMed ID: 25800972
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Bitopic Binding Mode of an M
    Bradley SJ; Molloy C; Bundgaard C; Mogg AJ; Thompson KJ; Dwomoh L; Sanger HE; Crabtree MD; Brooke SM; Sexton PM; Felder CC; Christopoulos A; Broad LM; Tobin AB; Langmead CJ
    Mol Pharmacol; 2018 Jun; 93(6):645-656. PubMed ID: 29695609
    [TBL] [Abstract][Full Text] [Related]  

  • 6. M1 muscarinic acetylcholine receptors: A therapeutic strategy for symptomatic and disease-modifying effects in Alzheimer's disease?
    Scarpa M; Hesse S; Bradley SJ
    Adv Pharmacol; 2020; 88():277-310. PubMed ID: 32416870
    [TBL] [Abstract][Full Text] [Related]  

  • 7. SAR studies on carboxylic acid series M(1) selective positive allosteric modulators (PAMs).
    Kuduk SD; Beshore DC
    Curr Top Med Chem; 2014; 14(15):1738-54. PubMed ID: 25176125
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Crystal structures of the M1 and M4 muscarinic acetylcholine receptors.
    Thal DM; Sun B; Feng D; Nawaratne V; Leach K; Felder CC; Bures MG; Evans DA; Weis WI; Bachhawat P; Kobilka TS; Sexton PM; Kobilka BK; Christopoulos A
    Nature; 2016 Mar; 531(7594):335-40. PubMed ID: 26958838
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Progress toward a high-affinity allosteric enhancer at muscarinic M1 receptors.
    Lazareno S; Popham A; Birdsall NJ
    J Mol Neurosci; 2003; 20(3):363-7. PubMed ID: 14501021
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Diverse Effects on M
    Rook JM; Abe M; Cho HP; Nance KD; Luscombe VB; Adams JJ; Dickerson JW; Remke DH; Garcia-Barrantes PM; Engers DW; Engers JL; Chang S; Foster JJ; Blobaum AL; Niswender CM; Jones CK; Conn PJ; Lindsley CW
    ACS Chem Neurosci; 2017 Apr; 8(4):866-883. PubMed ID: 28001356
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pharmacological characterization of LY593093, an M1 muscarinic acetylcholine receptor-selective partial orthosteric agonist.
    Watt ML; Schober DA; Hitchcock S; Liu B; Chesterfield AK; McKinzie D; Felder CC
    J Pharmacol Exp Ther; 2011 Aug; 338(2):622-32. PubMed ID: 21558436
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Characterization of a Novel M1 Muscarinic Acetylcholine Receptor Positive Allosteric Modulator Radioligand, [3H]PT-1284.
    Smith DL; Davoren JE; Edgerton JR; Lazzaro JT; Lee CW; Neal S; Zhang L; Grimwood S
    Mol Pharmacol; 2016 Sep; 90(3):177-87. PubMed ID: 27382013
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design and Synthesis of γ- and δ-Lactam M
    Davoren JE; Garnsey M; Pettersen B; Brodney MA; Edgerton JR; Fortin JP; Grimwood S; Harris AR; Jenkinson S; Kenakin T; Lazzaro JT; Lee CW; Lotarski SM; Nottebaum L; O'Neil SV; Popiolek M; Ramsey S; Steyn SJ; Thorn CA; Zhang L; Webb D
    J Med Chem; 2017 Aug; 60(15):6649-6663. PubMed ID: 28598634
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Opportunities and challenges for the development of M
    Nguyen HTM; van der Westhuizen ET; Langmead CJ; Tobin AB; Sexton PM; Christopoulos A; Valant C
    Br J Pharmacol; 2024 Jul; 181(14):2114-2142. PubMed ID: 36355830
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Assessment of the Molecular Mechanisms of Action of Novel 4-Phenylpyridine-2-One and 6-Phenylpyrimidin-4-One Allosteric Modulators at the M
    van der Westhuizen ET; Spathis A; Khajehali E; Jörg M; Mistry SN; Capuano B; Tobin AB; Sexton PM; Scammells PJ; Valant C; Christopoulos A
    Mol Pharmacol; 2018 Jul; 94(1):770-783. PubMed ID: 29691279
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The M1 muscarinic receptor allosteric agonists AC-42 and 1-[1'-(2-methylbenzyl)-1,4'-bipiperidin-4-yl]-1,3-dihydro-2H-benzimidazol-2-one bind to a unique site distinct from the acetylcholine orthosteric site.
    Jacobson MA; Kreatsoulas C; Pascarella DM; O'Brien JA; Sur C
    Mol Pharmacol; 2010 Oct; 78(4):648-57. PubMed ID: 20660086
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Evidence for Classical Cholinergic Toxicity Associated with Selective Activation of M1 Muscarinic Receptors.
    Alt A; Pendri A; Bertekap RL; Li G; Benitex Y; Nophsker M; Rockwell KL; Burford NT; Sum CS; Chen J; Herbst JJ; Ferrante M; Hendricson A; Cvijic ME; Westphal RS; O'Connell J; Banks M; Zhang L; Gentles RG; Jenkins S; Loy J; Macor JE
    J Pharmacol Exp Ther; 2016 Feb; 356(2):293-304. PubMed ID: 26582730
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and pharmacological profiling of analogues of benzyl quinolone carboxylic acid (BQCA) as allosteric modulators of the M1 muscarinic receptor.
    Mistry SN; Valant C; Sexton PM; Capuano B; Christopoulos A; Scammells PJ
    J Med Chem; 2013 Jun; 56(12):5151-72. PubMed ID: 23718562
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 4-Phenylpyridin-2-one Derivatives: A Novel Class of Positive Allosteric Modulator of the M1 Muscarinic Acetylcholine Receptor.
    Mistry SN; Jörg M; Lim H; Vinh NB; Sexton PM; Capuano B; Christopoulos A; Lane JR; Scammells PJ
    J Med Chem; 2016 Jan; 59(1):388-409. PubMed ID: 26624844
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and Pharmacological Evaluation of Heterocyclic Carboxamides: Positive Allosteric Modulators of the M
    Dallagnol JCC; Khajehali E; van der Westhuizen ET; Jörg M; Valant C; Gonçalves AG; Capuano B; Christopoulos A; Scammells PJ
    J Med Chem; 2018 Apr; 61(7):2875-2894. PubMed ID: 29544056
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.