BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

389 related articles for article (PubMed ID: 28360132)

  • 1. Dose-dependent transduction of Hedgehog relies on phosphorylation-based feedback between the G-protein-coupled receptor Smoothened and the kinase Fused.
    Sanial M; Bécam I; Hofmann L; Behague J; Argüelles C; Gourhand V; Bruzzone L; Holmgren RA; Plessis A
    Development; 2017 May; 144(10):1841-1850. PubMed ID: 28360132
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Regulation of Smoothened Phosphorylation and High-Level Hedgehog Signaling Activity by a Plasma Membrane Associated Kinase.
    Li S; Li S; Han Y; Tong C; Wang B; Chen Y; Jiang J
    PLoS Biol; 2016 Jun; 14(6):e1002481. PubMed ID: 27280464
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hedgehog signalling activity of Smoothened requires phosphorylation by protein kinase A and casein kinase I.
    Jia J; Tong C; Wang B; Luo L; Jiang J
    Nature; 2004 Dec; 432(7020):1045-50. PubMed ID: 15616566
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Fused-Costal2 protein complex regulates Hedgehog-induced Smo phosphorylation and cell-surface accumulation.
    Liu Y; Cao X; Jiang J; Jia J
    Genes Dev; 2007 Aug; 21(15):1949-63. PubMed ID: 17671093
    [TBL] [Abstract][Full Text] [Related]  

  • 5. High hedgehog signaling is transduced by a multikinase-dependent switch controlling the apico-basal distribution of the GPCR smoothened.
    Gonçalves Antunes M; Sanial M; Contremoulins V; Carvalho S; Plessis A; Becam I
    Elife; 2022 Sep; 11():. PubMed ID: 36083801
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phosphorylation of the atypical kinesin Costal2 by the kinase Fused induces the partial disassembly of the Smoothened-Fused-Costal2-Cubitus interruptus complex in Hedgehog signalling.
    Ruel L; Gallet A; Raisin S; Truchi A; Staccini-Lavenant L; Cervantes A; Thérond PP
    Development; 2007 Oct; 134(20):3677-89. PubMed ID: 17881487
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Evidence for a novel feedback loop in the Hedgehog pathway involving Smoothened and Fused.
    Claret S; Sanial M; Plessis A
    Curr Biol; 2007 Aug; 17(15):1326-33. PubMed ID: 17658259
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Sequential phosphorylation of smoothened transduces graded hedgehog signaling.
    Su Y; Ospina JK; Zhang J; Michelson AP; Schoen AM; Zhu AJ
    Sci Signal; 2011 Jul; 4(180):ra43. PubMed ID: 21730325
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hedgehog-regulated atypical PKC promotes phosphorylation and activation of Smoothened and Cubitus interruptus in Drosophila.
    Jiang K; Liu Y; Fan J; Epperly G; Gao T; Jiang J; Jia J
    Proc Natl Acad Sci U S A; 2014 Nov; 111(45):E4842-50. PubMed ID: 25349414
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hedgehog induces formation of PKA-Smoothened complexes to promote Smoothened phosphorylation and pathway activation.
    Li S; Ma G; Wang B; Jiang J
    Sci Signal; 2014 Jul; 7(332):ra62. PubMed ID: 24985345
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The last 59 amino acids of Smoothened cytoplasmic tail directly bind the protein kinase Fused and negatively regulate the Hedgehog pathway.
    Malpel S; Claret S; Sanial M; Brigui A; Piolot T; Daviet L; Martin-Lannerée S; Plessis A
    Dev Biol; 2007 Mar; 303(1):121-33. PubMed ID: 17182028
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hedgehog activates fused through phosphorylation to elicit a full spectrum of pathway responses.
    Zhou Q; Kalderon D
    Dev Cell; 2011 Jun; 20(6):802-14. PubMed ID: 21664578
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Distinct phosphorylations on kinesin costal-2 mediate differential hedgehog signaling strength.
    Ranieri N; Ruel L; Gallet A; Raisin S; Thérond PP
    Dev Cell; 2012 Feb; 22(2):279-94. PubMed ID: 22306085
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The contributions of protein kinase A and smoothened phosphorylation to hedgehog signal transduction in Drosophila melanogaster.
    Zhou Q; Apionishev S; Kalderon D
    Genetics; 2006 Aug; 173(4):2049-62. PubMed ID: 16783001
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Analysis of Smoothened Phosphorylation and Activation in Cultured Cells and Wing Discs of Drosophila.
    Jiang K; Jia J
    Methods Mol Biol; 2015; 1322():45-60. PubMed ID: 26179038
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Hedgehog-induced Smoothened conformational switch assembles a signaling complex that activates Fused by promoting its dimerization and phosphorylation.
    Shi Q; Li S; Jia J; Jiang J
    Development; 2011 Oct; 138(19):4219-31. PubMed ID: 21852395
    [TBL] [Abstract][Full Text] [Related]  

  • 17. G protein Galphai functions immediately downstream of Smoothened in Hedgehog signalling.
    Ogden SK; Fei DL; Schilling NS; Ahmed YF; Hwa J; Robbins DJ
    Nature; 2008 Dec; 456(7224):967-70. PubMed ID: 18987629
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Extensive phosphorylation of Smoothened in Hedgehog pathway activation.
    Zhang C; Williams EH; Guo Y; Lum L; Beachy PA
    Proc Natl Acad Sci U S A; 2004 Dec; 101(52):17900-7. PubMed ID: 15598741
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hedgehog signal transduction via Smoothened association with a cytoplasmic complex scaffolded by the atypical kinesin, Costal-2.
    Lum L; Zhang C; Oh S; Mann RK; von Kessler DP; Taipale J; Weis-Garcia F; Gong R; Wang B; Beachy PA
    Mol Cell; 2003 Nov; 12(5):1261-74. PubMed ID: 14636583
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Stability and association of Smoothened, Costal2 and Fused with Cubitus interruptus are regulated by Hedgehog.
    Ruel L; Rodriguez R; Gallet A; Lavenant-Staccini L; Thérond PP
    Nat Cell Biol; 2003 Oct; 5(10):907-13. PubMed ID: 14523402
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.