BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 28364040)

  • 1. Hypoxia reduces HNF4α/MODY1 protein expression in pancreatic β-cells by activating AMP-activated protein kinase.
    Sato Y; Tsuyama T; Sato C; Karim MF; Yoshizawa T; Inoue M; Yamagata K
    J Biol Chem; 2017 May; 292(21):8716-8728. PubMed ID: 28364040
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hepatocyte nuclear factor-4alpha involved in type 1 maturity-onset diabetes of the young is a novel target of AMP-activated protein kinase.
    Leclerc I; Lenzner C; Gourdon L; Vaulont S; Kahn A; Viollet B
    Diabetes; 2001 Jul; 50(7):1515-21. PubMed ID: 11423471
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The MODY1 gene for hepatocyte nuclear factor 4alpha and a feedback loop control COUP-TFII expression in pancreatic beta cells.
    Perilhou A; Tourrel-Cuzin C; Zhang P; Kharroubi I; Wang H; Fauveau V; Scott DK; Wollheim CB; Vasseur-Cognet M
    Mol Cell Biol; 2008 Jul; 28(14):4588-97. PubMed ID: 18474611
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Roles of HNF1α and HNF4α in pancreatic β-cells: lessons from a monogenic form of diabetes (MODY).
    Yamagata K
    Vitam Horm; 2014; 95():407-23. PubMed ID: 24559927
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metformin attenuates angiotensin II-induced TGFβ1 expression by targeting hepatocyte nuclear factor-4-α.
    Chen R; Feng Y; Wu J; Song Y; Li H; Shen Q; Li D; Zhang J; Lu Z; Xiao H; Zhang Y
    Br J Pharmacol; 2018 Apr; 175(8):1217-1229. PubMed ID: 28230250
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hepatocyte nuclear factor 4alpha regulates the expression of pancreatic beta -cell genes implicated in glucose metabolism and nutrient-induced insulin secretion.
    Wang H; Maechler P; Antinozzi PA; Hagenfeldt KA; Wollheim CB
    J Biol Chem; 2000 Nov; 275(46):35953-9. PubMed ID: 10967120
    [TBL] [Abstract][Full Text] [Related]  

  • 7. MED25 is a mediator component of HNF4α-driven transcription leading to insulin secretion in pancreatic beta-cells.
    Han EH; Rha GB; Chi YI
    PLoS One; 2012; 7(8):e44007. PubMed ID: 22952853
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Expression of HNF4alpha variants in pancreatic islets and Ins-1 beta cells.
    Huang J; Karakucuk V; Levitsky LL; Rhoads DB
    Diabetes Metab Res Rev; 2008 Oct; 24(7):533-43. PubMed ID: 18561282
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The maturity-onset diabetes of the young (MODY1) transcription factor HNF4alpha regulates expression of genes required for glucose transport and metabolism.
    Stoffel M; Duncan SA
    Proc Natl Acad Sci U S A; 1997 Nov; 94(24):13209-14. PubMed ID: 9371825
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Transcriptional Regulation of X-Box-binding Protein One (XBP1) by Hepatocyte Nuclear Factor 4α (HNF4Α) Is Vital to Beta-cell Function.
    Moore BD; Jin RU; Lo H; Jung M; Wang H; Battle MA; Wollheim CB; Urano F; Mills JC
    J Biol Chem; 2016 Mar; 291(12):6146-57. PubMed ID: 26792861
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ErbB3-binding protein 1 (EBP1) represses HNF4α-mediated transcription and insulin secretion in pancreatic β-cells.
    Han EH; Singh P; Lee IK; Urrutia R; Chi YI
    J Biol Chem; 2019 Sep; 294(38):13983-13994. PubMed ID: 31362984
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel mechanisms of regulation of the expression and transcriptional activity of hepatocyte nuclear factor 4α.
    Guo S; Lu H
    J Cell Biochem; 2019 Jan; 120(1):519-532. PubMed ID: 30191603
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation of Pancreatic β Cell Mass by Cross-Interaction between CCAAT Enhancer Binding Protein β Induced by Endoplasmic Reticulum Stress and AMP-Activated Protein Kinase Activity.
    Matsuda T; Takahashi H; Mieda Y; Shimizu S; Kawamoto T; Matsuura Y; Takai T; Suzuki E; Kanno A; Koyanagi-Kimura M; Asahara S; Bartolome A; Yokoi N; Inoue H; Ogawa W; Seino S; Kido Y
    PLoS One; 2015; 10(6):e0130757. PubMed ID: 26091000
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The G115S mutation associated with maturity-onset diabetes of the young impairs hepatocyte nuclear factor 4alpha activities and introduces a PKA phosphorylation site in its DNA-binding domain.
    Oxombre B; Kouach M; Moerman E; Formstecher P; Laine B
    Biochem J; 2004 Nov; 383(Pt. 3):573-80. PubMed ID: 15233628
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Sustained expression of hepatocyte nuclear factor-6 leads to loss of pancreatic beta-cells by apoptosis.
    Hara M; Shen J; Pugh W; Polonsky KS; Le Beau MM; Bell GI
    Exp Clin Endocrinol Diabetes; 2007 Nov; 115(10):654-61. PubMed ID: 18058600
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Functional characterization of the HNF4alpha isoform (HNF4alpha8) expressed in pancreatic beta-cells.
    Ihara A; Yamagata K; Nammo T; Miura A; Yuan M; Tanaka T; Sladek FM; Matsuzawa Y; Miyagawa J; Shimomura I
    Biochem Biophys Res Commun; 2005 Apr; 329(3):984-90. PubMed ID: 15752752
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The flavonoid derivative 4'-nitro-6-hydroxyflavone suppresses the activity of HNF4α and stimulates the degradation of HNF4α protein through the activation of AMPK.
    Inoue J; Ikeda S; Kanayama T; Sato R
    Biosci Biotechnol Biochem; 2017 Aug; 81(8):1548-1552. PubMed ID: 28475422
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Role of AMPK in pancreatic beta cell function.
    Fu A; Eberhard CE; Screaton RA
    Mol Cell Endocrinol; 2013 Feb; 366(2):127-34. PubMed ID: 22766107
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tissue-specific transcription factor HNF4alpha inhibits cell proliferation and induces apoptosis in the pancreatic INS-1 beta-cell line.
    Erdmann S; Senkel S; Arndt T; Lucas B; Lausen J; Klein-Hitpass L; Ryffel GU; Thomas H
    Biol Chem; 2007 Jan; 388(1):91-106. PubMed ID: 17214554
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hepatocyte Nuclear Factor 4-α (HNF4α) controls the insulin resistance-induced pancreatic β-cell mass expansion.
    Barth R; Ruoso C; Ferreira SM; de Ramos FC; Lima FB; Boschero AC; Santos GJD
    Life Sci; 2022 Jan; 289():120213. PubMed ID: 34902439
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.