BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

621 related articles for article (PubMed ID: 28369484)

  • 21. MRN complex is an essential effector of DNA damage repair.
    Qiu S; Huang J
    J Zhejiang Univ Sci B; 2021 Jan; 22(1):31-37. PubMed ID: 33448185
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Interplay with the Mre11-Rad50-Nbs1 complex and phosphorylation by GSK3β implicate human B-Myb in DNA-damage signaling.
    Henrich SM; Usadel C; Werwein E; Burdova K; Janscak P; Ferrari S; Hess D; Klempnauer KH
    Sci Rep; 2017 Jan; 7():41663. PubMed ID: 28128338
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Purification and biochemical characterization of ataxia-telangiectasia mutated and Mre11/Rad50/Nbs1.
    Lee JH; Paull TT
    Methods Enzymol; 2006; 408():529-39. PubMed ID: 16793391
    [TBL] [Abstract][Full Text] [Related]  

  • 24. The Mre11/Rad50/Nbs1 complex plays an important role in the prevention of DNA rereplication in mammalian cells.
    Lee AY; Liu E; Wu X
    J Biol Chem; 2007 Nov; 282(44):32243-55. PubMed ID: 17715134
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Two-step activation of ATM by DNA and the Mre11-Rad50-Nbs1 complex.
    Dupré A; Boyer-Chatenet L; Gautier J
    Nat Struct Mol Biol; 2006 May; 13(5):451-7. PubMed ID: 16622404
    [TBL] [Abstract][Full Text] [Related]  

  • 26. The Mre11-Rad50-Nbs1 complex mediates activation of TopBP1 by ATM.
    Yoo HY; Kumagai A; Shevchenko A; Shevchenko A; Dunphy WG
    Mol Biol Cell; 2009 May; 20(9):2351-60. PubMed ID: 19279141
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Mre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity.
    Jazayeri A; Balestrini A; Garner E; Haber JE; Costanzo V
    EMBO J; 2008 Jul; 27(14):1953-62. PubMed ID: 18596698
    [TBL] [Abstract][Full Text] [Related]  

  • 28. A murine model of Nijmegen breakage syndrome.
    Williams BR; Mirzoeva OK; Morgan WF; Lin J; Dunnick W; Petrini JH
    Curr Biol; 2002 Apr; 12(8):648-53. PubMed ID: 11967151
    [TBL] [Abstract][Full Text] [Related]  

  • 29. NBS1 promotes the endonuclease activity of the MRE11-RAD50 complex by sensing CtIP phosphorylation.
    Anand R; Jasrotia A; Bundschuh D; Howard SM; Ranjha L; Stucki M; Cejka P
    EMBO J; 2019 Apr; 38(7):. PubMed ID: 30787182
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex.
    Lee JH; Paull TT
    Science; 2004 Apr; 304(5667):93-6. PubMed ID: 15064416
    [TBL] [Abstract][Full Text] [Related]  

  • 31. ATP puts the brake on DNA double-strand break repair: a new study shows that ATP switches the Mre11-Rad50-Nbs1 repair factor between signaling and processing of DNA ends.
    Hopfner KP
    Bioessays; 2014 Dec; 36(12):1170-8. PubMed ID: 25213441
    [TBL] [Abstract][Full Text] [Related]  

  • 32. ATM and the Mre11-Rad50-Nbs1 complex respond to nucleoside analogue-induced stalled replication forks and contribute to drug resistance.
    Ewald B; Sampath D; Plunkett W
    Cancer Res; 2008 Oct; 68(19):7947-55. PubMed ID: 18829552
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Rad50 zinc hook is important for the Mre11 complex to bind chromosomal DNA double-stranded breaks and initiate various DNA damage responses.
    He J; Shi LZ; Truong LN; Lu CS; Razavian N; Li Y; Negrete A; Shiloach J; Berns MW; Wu X
    J Biol Chem; 2012 Sep; 287(38):31747-56. PubMed ID: 22833675
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Loss of the tumor suppressor BIN1 enables ATM Ser/Thr kinase activation by the nuclear protein E2F1 and renders cancer cells resistant to cisplatin.
    Folk WP; Kumari A; Iwasaki T; Pyndiah S; Johnson JC; Cassimere EK; Abdulovic-Cui AL; Sakamuro D
    J Biol Chem; 2019 Apr; 294(14):5700-5719. PubMed ID: 30733337
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Requirement of the MRN complex for ATM activation by DNA damage.
    Uziel T; Lerenthal Y; Moyal L; Andegeko Y; Mittelman L; Shiloh Y
    EMBO J; 2003 Oct; 22(20):5612-21. PubMed ID: 14532133
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Double-strand breaks in ribosomal RNA genes activate a distinct signaling and chromatin response to facilitate nucleolar restructuring and repair.
    Korsholm LM; Gál Z; Lin L; Quevedo O; Ahmad DA; Dulina E; Luo Y; Bartek J; Larsen DH
    Nucleic Acids Res; 2019 Sep; 47(15):8019-8035. PubMed ID: 31184714
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Cell cycle-and proteasome-dependent formation of etoposide-induced replication protein A (RPA) or Mre11/Rad50/Nbs1 (MRN) complex repair foci.
    Robison JG; Dixon K; Bissler JJ
    Cell Cycle; 2007 Oct; 6(19):2399-407. PubMed ID: 17700069
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Resection of DNA double-strand breaks activates Mre11-Rad50-Nbs1- and Rad9-Hus1-Rad1-dependent mechanisms that redundantly promote ATR checkpoint activation and end processing in Xenopus egg extracts.
    Tatsukawa K; Sakamoto R; Kawasoe Y; Kubota Y; Tsurimoto T; Takahashi TS; Ohashi E
    Nucleic Acids Res; 2024 Apr; 52(6):3146-3163. PubMed ID: 38349040
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Dancing on damaged chromatin: functions of ATM and the RAD50/MRE11/NBS1 complex in cellular responses to DNA damage.
    Iijima K; Ohara M; Seki R; Tauchi H
    J Radiat Res; 2008 Sep; 49(5):451-64. PubMed ID: 18772547
    [TBL] [Abstract][Full Text] [Related]  

  • 40. NBS1 Phosphorylation Status Dictates Repair Choice of Dysfunctional Telomeres.
    Rai R; Hu C; Broton C; Chen Y; Lei M; Chang S
    Mol Cell; 2017 Mar; 65(5):801-817.e4. PubMed ID: 28216226
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 32.