These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

562 related articles for article (PubMed ID: 28370287)

  • 1. A functional mammalian target of rapamycin complex 1 signaling is indispensable for c-Myc-driven hepatocarcinogenesis.
    Liu P; Ge M; Hu J; Li X; Che L; Sun K; Cheng L; Huang Y; Pilo MG; Cigliano A; Pes GM; Pascale RM; Brozzetti S; Vidili G; Porcu A; Cossu A; Palmieri G; Sini MC; Ribback S; Dombrowski F; Tao J; Calvisi DF; Chen L; Chen X
    Hepatology; 2017 Jul; 66(1):167-181. PubMed ID: 28370287
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 4EBP1/eIF4E and p70S6K/RPS6 axes play critical and distinct roles in hepatocarcinogenesis driven by AKT and N-Ras proto-oncogenes in mice.
    Wang C; Cigliano A; Jiang L; Li X; Fan B; Pilo MG; Liu Y; Gui B; Sini M; Smith JW; Dombrowski F; Calvisi DF; Evert M; Chen X
    Hepatology; 2015 Jan; 61(1):200-13. PubMed ID: 25145583
    [TBL] [Abstract][Full Text] [Related]  

  • 3. AKT inhibition overcomes rapamycin resistance by enhancing the repressive function of PRAS40 on mTORC1/4E-BP1 axis.
    Mi W; Ye Q; Liu S; She QB
    Oncotarget; 2015 Jun; 6(16):13962-77. PubMed ID: 25961827
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pivotal Role of Fatty Acid Synthase in c-MYC Driven Hepatocarcinogenesis.
    Jia J; Che L; Cigliano A; Wang X; Peitta G; Tao J; Zhong S; Ribback S; Evert M; Chen X; Calvisi DF
    Int J Mol Sci; 2020 Nov; 21(22):. PubMed ID: 33187130
    [TBL] [Abstract][Full Text] [Related]  

  • 5. GSK-3 directly regulates phospho-4EBP1 in renal cell carcinoma cell-line: an intrinsic subcellular mechanism for resistance to mTORC1 inhibition.
    Ito H; Ichiyanagi O; Naito S; Bilim VN; Tomita Y; Kato T; Nagaoka A; Tsuchiya N
    BMC Cancer; 2016 Jul; 16():393. PubMed ID: 27387559
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Feedback loops blockade potentiates apoptosis induction and antitumor activity of a novel AKT inhibitor DC120 in human liver cancer.
    Yang F; Deng R; Qian XJ; Chang SH; Wu XQ; Qin J; Feng GK; Ding K; Zhu XF
    Cell Death Dis; 2014 Mar; 5(3):e1114. PubMed ID: 24625973
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hepatitis C virus NS5A binds to the mRNA cap-binding eukaryotic translation initiation 4F (eIF4F) complex and up-regulates host translation initiation machinery through eIF4E-binding protein 1 inactivation.
    George A; Panda S; Kudmulwar D; Chhatbar SP; Nayak SC; Krishnan HH
    J Biol Chem; 2012 Feb; 287(7):5042-58. PubMed ID: 22184107
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Reciprocal regulation of mTOR complexes in pancreatic islets from humans with type 2 diabetes.
    Yuan T; Rafizadeh S; Gorrepati KD; Lupse B; Oberholzer J; Maedler K; Ardestani A
    Diabetologia; 2017 Apr; 60(4):668-678. PubMed ID: 28004151
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The mammalian target of rapamycin regulates cholesterol biosynthetic gene expression and exhibits a rapamycin-resistant transcriptional profile.
    Wang BT; Ducker GS; Barczak AJ; Barbeau R; Erle DJ; Shokat KM
    Proc Natl Acad Sci U S A; 2011 Sep; 108(37):15201-6. PubMed ID: 21876130
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ciclopirox olamine inhibits mTORC1 signaling by activation of AMPK.
    Zhou H; Shang C; Wang M; Shen T; Kong L; Yu C; Ye Z; Luo Y; Liu L; Li Y; Huang S
    Biochem Pharmacol; 2016 Sep; 116():39-50. PubMed ID: 27396756
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ASCT2 silencing regulates mammalian target-of-rapamycin growth and survival signaling in human hepatoma cells.
    Fuchs BC; Finger RE; Onan MC; Bode BP
    Am J Physiol Cell Physiol; 2007 Jul; 293(1):C55-63. PubMed ID: 17329400
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Yes-associated protein 1 and transcriptional coactivator with PDZ-binding motif activate the mammalian target of rapamycin complex 1 pathway by regulating amino acid transporters in hepatocellular carcinoma.
    Park YY; Sohn BH; Johnson RL; Kang MH; Kim SB; Shim JJ; Mangala LS; Kim JH; Yoo JE; Rodriguez-Aguayo C; Pradeep S; Hwang JE; Jang HJ; Lee HS; Rupaimoole R; Lopez-Berestein G; Jeong W; Park IS; Park YN; Sood AK; Mills GB; Lee JS
    Hepatology; 2016 Jan; 63(1):159-72. PubMed ID: 26389641
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Co-activation of AKT and c-Met triggers rapid hepatocellular carcinoma development via the mTORC1/FASN pathway in mice.
    Hu J; Che L; Li L; Pilo MG; Cigliano A; Ribback S; Li X; Latte G; Mela M; Evert M; Dombrowski F; Zheng G; Chen X; Calvisi DF
    Sci Rep; 2016 Feb; 6():20484. PubMed ID: 26857837
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The synergistic inhibition of breast cancer proliferation by combined treatment with 4EGI-1 and MK2206.
    Wang H; Huang F; Wang J; Wang P; Lv W; Hong L; Li S; Zhou J
    Cell Cycle; 2015; 14(2):232-42. PubMed ID: 25607647
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Improvement of mTORC1-driven overproduction of apoB-containing triacylglyceride-rich lipoproteins by short-chain fatty acids, 4-phenylbutyric acid and (R)-α-lipoic acid, in human hepatocellular carcinoma cells.
    Roberts JL; He B; Erickson A; Moreau R
    Biochim Biophys Acta; 2016 Mar; 1861(3):166-76. PubMed ID: 26680362
    [TBL] [Abstract][Full Text] [Related]  

  • 16. mTORC1 Up-Regulates GP73 to Promote Proliferation and Migration of Hepatocellular Carcinoma Cells and Growth of Xenograft Tumors in Mice.
    Chen X; Wang Y; Tao J; Shi Y; Gai X; Huang F; Ma Q; Zhou Z; Chen H; Zhang H; Liu Z; Sun Q; Peng H; Chen R; Jing Y; Yang H; Mao Y; Zhang H
    Gastroenterology; 2015 Sep; 149(3):741-52.e14. PubMed ID: 25980751
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mammalian target of rapamycin complex 1 activation is required for the stimulation of human skeletal muscle protein synthesis by essential amino acids.
    Dickinson JM; Fry CS; Drummond MJ; Gundermann DM; Walker DK; Glynn EL; Timmerman KL; Dhanani S; Volpi E; Rasmussen BB
    J Nutr; 2011 May; 141(5):856-62. PubMed ID: 21430254
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SLC1A5 glutamine transporter is a target of MYC and mediates reduced mTORC1 signaling and increased fatty acid oxidation in long-lived Myc hypomorphic mice.
    Zhao X; Petrashen AP; Sanders JA; Peterson AL; Sedivy JM
    Aging Cell; 2019 Jun; 18(3):e12947. PubMed ID: 30909319
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Site-specific mTOR phosphorylation promotes mTORC1-mediated signaling and cell growth.
    Acosta-Jaquez HA; Keller JA; Foster KG; Ekim B; Soliman GA; Feener EP; Ballif BA; Fingar DC
    Mol Cell Biol; 2009 Aug; 29(15):4308-24. PubMed ID: 19487463
    [TBL] [Abstract][Full Text] [Related]  

  • 20. High-dose rapamycin induces apoptosis in human cancer cells by dissociating mTOR complex 1 and suppressing phosphorylation of 4E-BP1.
    Yellen P; Saqcena M; Salloum D; Feng J; Preda A; Xu L; Rodrik-Outmezguine V; Foster DA
    Cell Cycle; 2011 Nov; 10(22):3948-56. PubMed ID: 22071574
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 29.