BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

74 related articles for article (PubMed ID: 2837246)

  • 1. N2-substituted guanine derivatives act as selective non substrate inhibitors of HSV I thymidine kinase.
    Focher F; Sangalli S; Ciarrocchi G; Della Valle G; Talarico D; Rebuzzini A; Wright G; Brown N; Spadari S
    Biochem Pharmacol; 1988 May; 37(9):1877-8. PubMed ID: 2837246
    [No Abstract]   [Full Text] [Related]  

  • 2. Structure-activity relationships of N2-substituted guanines as inhibitors of HSV1 and HSV2 thymidine kinases.
    Hildebrand C; Sandoli D; Focher F; Gambino J; Ciarrocchi G; Spadari S; Wright G
    J Med Chem; 1990 Jan; 33(1):203-6. PubMed ID: 2153203
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Nucleoside analogs as non-substrate inhibitors of herpes simplex viruses thymidine kinase.
    Focher F; Sandoli D; Hildebrand C; Sangalli S; Ciarrocchi G; Rebuzzini A; Pedrali-Noy G; Manservigi R; Wright G; Brown N
    Methods Find Exp Clin Pharmacol; 1989 Sep; 11(9):577-82. PubMed ID: 2555637
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Quantitative structure-activity relationships of N2-phenylguanines as inhibitors of herpes simplex virus thymidine kinases.
    Gambino J; Focher F; Hildebrand C; Maga G; Noonan T; Spadari S; Wright G
    J Med Chem; 1992 Aug; 35(16):2979-83. PubMed ID: 1323680
    [TBL] [Abstract][Full Text] [Related]  

  • 5. N2-phenyldeoxyguanosine: a novel selective inhibitor of herpes simplex thymidine kinase.
    Focher F; Hildebrand C; Freese S; Ciarrocchi G; Noonan T; Sangalli S; Brown N; Spadari S; Wright G
    J Med Chem; 1988 Aug; 31(8):1496-500. PubMed ID: 2840499
    [TBL] [Abstract][Full Text] [Related]  

  • 6. QSAR and molecular graphics analysis of N2-phenylguanines as inhibitors of herpes simplex virus thymidine kinases.
    Gaudio AC; Richards WG; Takahata Y
    J Mol Graph Model; 2000 Feb; 18(1):33-41. PubMed ID: 10935205
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Specific inhibitors of herpes simplex virus thymidine kinase diminish reactivation of latent virus from explanted murine ganglia.
    Leib DA; Ruffner KL; Hildebrand C; Schaffer PA; Wright GE; Coen DM
    Antimicrob Agents Chemother; 1990 Jun; 34(6):1285-6. PubMed ID: 2168150
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Thymidine kinase from herpes simplex virus phosphorylates the new antiviral compound, 9-(2-hydroxyethoxymethyl)guanine.
    Fyfe JA; Keller PM; Furman PA; Miller RL; Elion GB
    J Biol Chem; 1978 Dec; 253(24):8721-7. PubMed ID: 214430
    [No Abstract]   [Full Text] [Related]  

  • 9. Efficiency of phosphorylation of the cyclobut-G (A-69992) enantiomers by HSV-1 thymidine kinase does not correlate with their anti-herpesvirus activity.
    Kohlbrenner WE; Carter CD; Fesik SW; Norbeck DW; Erickson J
    Biochem Pharmacol; 1990 Dec; 40(11):R5-10. PubMed ID: 2176497
    [No Abstract]   [Full Text] [Related]  

  • 10. Modelling of guanine-derivative--protein interaction complexes as a basis of drug design.
    Folkers G; Prota A; Merz A
    Farmaco; 1995 Jun; 50(6):449-54. PubMed ID: 7669183
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Nucleoside analogues as highly potent and selective inhibitors of herpes simplex virus thymidine kinase.
    Martin JA; Lambert RW; Merrett JH; Parkes KE; Thomas GJ; Baker SJ; Bushnell DJ; Cansfield JE; Dunsdon SJ; Freeman AC; Hopkins RA; Johns IR; Keech E; Simmonite H; Walmsley A; Wong Kai-In P; Holland M
    Bioorg Med Chem Lett; 2001 Jul; 11(13):1655-8. PubMed ID: 11425530
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of herpes simplex virus thymidine kinases by 2-phenylamino-6-oxopurines and related compounds: structure-activity relationships and antiherpetic activity in vivo.
    Manikowski A; Verri A; Lossani A; Gebhardt BM; Gambino J; Focher F; Spadari S; Wright GE
    J Med Chem; 2005 Jun; 48(11):3919-29. PubMed ID: 15916444
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The chemotherapeutic exploitation of virus-specified enzymes.
    Elion GB
    Adv Enzyme Regul; 1980; 18():53-66. PubMed ID: 6255770
    [No Abstract]   [Full Text] [Related]  

  • 14. Altered substrate specificity of herpes simplex virus thymidine kinase confers acyclovir-resistance.
    Darby G; Field HJ; Salisbury SA
    Nature; 1981 Jan; 289(5793):81-3. PubMed ID: 6256650
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Non-nucleoside inhibitors of mitochondrial thymidine kinase (TK-2) differentially inhibit the closely related herpes simplex virus type 1 TK and Drosophila melanogaster multifunctional deoxynucleoside kinase.
    Balzarini J; Hernández AI; Roche P; Esnouf R; Karlsson A; Camarasa MJ; Pérez-Pérez MJ
    Mol Pharmacol; 2003 Feb; 63(2):263-70. PubMed ID: 12527796
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Selective modification of thymidine by dansyl group and biological effects of the dansyl derivatives.
    Bonora GM; Palù G
    Biochem Pharmacol; 1988 May; 37(9):1849-50. PubMed ID: 2837243
    [No Abstract]   [Full Text] [Related]  

  • 17. Comparison of thymidine kinase activities indiced in cells productively infected with herpesvirus saimiri and herpes simplex virus.
    Honess RW; O'Hare P; Young D
    J Gen Virol; 1982 Feb; 58(Pt 2):237-49. PubMed ID: 6278057
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of herpes simplex virus type 1 DNA polymerase by [1R(1 alpha,2 beta,3 alpha)]-9-[2,3-bis(hydroxymethyl)cyclobutyl] guanine.
    Terry BJ; Cianci CW; Hagen ME
    Mol Pharmacol; 1991 Oct; 40(4):591-6. PubMed ID: 1656194
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Understanding the binding of 5-substituted 2'-deoxyuridine substrates to thymidine kinase of herpes simplex virus type-1.
    De Winter H; Herdewijn P
    J Med Chem; 1996 Nov; 39(24):4727-37. PubMed ID: 8941385
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Preclinical evaluation of the penciclovir analog 9-(4-[(18)F]fluoro-3-hydroxymethylbutyl)guanine for in vivo measurement of suicide gene expression with PET.
    Alauddin MM; Shahinian A; Gordon EM; Bading JR; Conti PS
    J Nucl Med; 2001 Nov; 42(11):1682-90. PubMed ID: 11696640
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.