321 related articles for article (PubMed ID: 28384547)
21. 3-(3-Butylamino-2-hydroxy-propoxy)-1-hydroxy-xanthen-9-one acts as a topoisomerase IIα catalytic inhibitor with low DNA damage.
Park SE; Chang IH; Jun KY; Lee E; Lee ES; Na Y; Kwon Y
Eur J Med Chem; 2013 Nov; 69():139-45. PubMed ID: 24013413
[TBL] [Abstract][Full Text] [Related]
22. Synthesis and structure-activity relationships of hydroxylated and halogenated 2,4-diaryl benzofuro[3,2-b]pyridin-7-ols as selective topoisomerase IIα inhibitors.
Thapa Magar TB; Hee Seo S; Shrestha A; Kim JA; Kunwar S; Bist G; Kwon Y; Lee ES
Bioorg Chem; 2021 Jun; 111():104884. PubMed ID: 33872925
[TBL] [Abstract][Full Text] [Related]
23. Fluorescein hydrazones: A series of novel non-intercalative topoisomerase IIα catalytic inhibitors induce G1 arrest and apoptosis in breast and colon cancer cells.
Islam MS; Park S; Song C; Kadi AA; Kwon Y; Rahman AF
Eur J Med Chem; 2017 Jan; 125():49-67. PubMed ID: 27654394
[TBL] [Abstract][Full Text] [Related]
24. Development of 13H-benzo[f]chromeno[4,3-b][1,7]naphthyridines and their salts as potent cytotoxic agents and topoisomerase I/IIα inhibitors.
Arepalli SK; Lee C; Sim S; Lee K; Jo H; Jun KY; Kwon Y; Kang JS; Jung JK; Lee H
Bioorg Med Chem; 2018 Oct; 26(18):5181-5193. PubMed ID: 30253887
[TBL] [Abstract][Full Text] [Related]
25. Dihydroxylated 2,4,6-triphenyl pyridines: synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study.
Karki R; Thapa P; Yoo HY; Kadayat TM; Park PH; Na Y; Lee E; Jeon KH; Cho WJ; Choi H; Kwon Y; Lee ES
Eur J Med Chem; 2012 Mar; 49():219-28. PubMed ID: 22318164
[TBL] [Abstract][Full Text] [Related]
26. Synthesis, antitumor activity, and structure-activity relationship study of trihydroxylated 2,4,6-triphenyl pyridines as potent and selective topoisomerase II inhibitors.
Karki R; Park C; Jun KY; Jee JG; Lee JH; Thapa P; Kadayat TM; Kwon Y; Lee ES
Eur J Med Chem; 2014 Sep; 84():555-65. PubMed ID: 25062006
[TBL] [Abstract][Full Text] [Related]
27. Effect of chlorine substituent on cytotoxic activities: Design and synthesis of systematically modified 2,4-diphenyl-5H-indeno[1,2-b]pyridines.
Kadayat TM; Park S; Jun KY; Magar TB; Bist G; Shrestha A; Na Y; Kwon Y; Lee ES
Bioorg Med Chem Lett; 2016 Apr; 26(7):1726-31. PubMed ID: 26927425
[TBL] [Abstract][Full Text] [Related]
28. Design and Synthesis of Arylnaphthalene Lignan Lactone Derivatives as Potent Topoisomerase Inhibitors.
Chen W; Feng Z; Hu D; Meng J
Med Chem; 2021; 17(8):856-865. PubMed ID: 32520691
[TBL] [Abstract][Full Text] [Related]
29. 2-Chlorophenyl-substituted benzofuro[3,2-b]pyridines with enhanced topoisomerase inhibitory activity: The role of the chlorine substituent.
Thapa Magar TB; Kadayat TM; Lee HJ; Park S; Bist G; Shrestha A; Kwon Y; Lee ES
Bioorg Med Chem Lett; 2017 Aug; 27(15):3279-3283. PubMed ID: 28633898
[TBL] [Abstract][Full Text] [Related]
30. Synthesis and biological evaluation of N-(carbobenzyloxy)-l-phenylalanine and N-(carbobenzyloxy)-l-aspartic acid-β-benzyl ester derivatives as potent topoisomerase IIα inhibitors.
Han X; Zhong Y; Zhou G; Qi H; Li S; Ding Q; Liu Z; Song Y; Qiao X
Bioorg Med Chem; 2017 Jun; 25(12):3116-3126. PubMed ID: 28462840
[TBL] [Abstract][Full Text] [Related]
31. Di-indenopyridines as topoisomerase II-selective anticancer agents: Design, synthesis, and structure-activity relationships.
Shrestha A; Hwang SY; Kunwar S; Man Kadayat T; Park S; Liu Y; Jo H; Sheen N; Seo M; Lee ES; Kwon Y
Bioorg Med Chem; 2023 Aug; 91():117403. PubMed ID: 37418826
[TBL] [Abstract][Full Text] [Related]
32. A series of novel terpyridine-skeleton molecule derivants inhibit tumor growth and metastasis by targeting topoisomerases.
Kwon HB; Park C; Jeon KH; Lee E; Park SE; Jun KY; Kadayat TM; Thapa P; Karki R; Na Y; Park MS; Rho SB; Lee ES; Kwon Y
J Med Chem; 2015 Feb; 58(3):1100-22. PubMed ID: 25603122
[TBL] [Abstract][Full Text] [Related]
33. Synthesis and biological evaluation of benzo[a]phenazine derivatives as a dual inhibitor of topoisomerase I and II.
Zhuo ST; Li CY; Hu MH; Chen SB; Yao PF; Huang SL; Ou TM; Tan JH; An LK; Li D; Gu LQ; Huang ZS
Org Biomol Chem; 2013 Jun; 11(24):3989-4005. PubMed ID: 23657605
[TBL] [Abstract][Full Text] [Related]
34. Structure-guided optimization of 4,6-substituted-1,3,5-triazin-2(1H)-ones as catalytic inhibitors of human DNA topoisomerase IIα.
Bergant K; Janežič M; Valjavec K; Sosič I; Pajk S; Štampar M; Žegura B; Gobec S; Filipič M; Perdih A
Eur J Med Chem; 2019 Aug; 175():330-348. PubMed ID: 31096154
[TBL] [Abstract][Full Text] [Related]
35. A new phenolic series of indenopyridinone as topoisomerase inhibitors: Design, synthesis, and structure-activity relationships.
Shrestha A; Park S; Jang HJ; Katila P; Shrestha R; Kwon Y; Lee ES
Bioorg Med Chem; 2018 Oct; 26(18):5212-5223. PubMed ID: 30262132
[TBL] [Abstract][Full Text] [Related]
36. Design, synthesis and systematic evaluation of cytotoxic 3-heteroarylisoquinolinamines as topoisomerases inhibitors.
My Van HT; Woo H; Jeong HM; Khadka DB; Yang SH; Zhao C; Jin Y; Lee ES; Youl Lee K; Kwon Y; Cho WJ
Eur J Med Chem; 2014 Jul; 82():181-94. PubMed ID: 24904965
[TBL] [Abstract][Full Text] [Related]
37. Design, synthesis and biological evaluation of novel perimidine o-quinone derivatives as non-intercalative topoisomerase II catalytic inhibitors.
Zhou DC; Lu YT; Mai YW; Zhang C; Xia J; Yao PF; Wang HG; Huang SL; Huang ZS
Bioorg Chem; 2019 Oct; 91():103131. PubMed ID: 31377387
[TBL] [Abstract][Full Text] [Related]
38. Synthesis of carbazole derivatives containing chalcone analogs as non-intercalative topoisomerase II catalytic inhibitors and apoptosis inducers.
Li PH; Jiang H; Zhang WJ; Li YL; Zhao MC; Zhou W; Zhang LY; Tang YD; Dong CZ; Huang ZS; Chen HX; Du ZY
Eur J Med Chem; 2018 Feb; 145():498-510. PubMed ID: 29335211
[TBL] [Abstract][Full Text] [Related]
39. Gambogic acid inhibits the catalytic activity of human topoisomerase IIalpha by binding to its ATPase domain.
Qin Y; Meng L; Hu C; Duan W; Zuo Z; Lin L; Zhang X; Ding J
Mol Cancer Ther; 2007 Sep; 6(9):2429-40. PubMed ID: 17876042
[TBL] [Abstract][Full Text] [Related]
40. Design and synthesis of 3,5-substituted 1,2,4-oxadiazoles as catalytic inhibitors of human DNA topoisomerase IIα.
Loboda KB; Valjavec K; Štampar M; Wolber G; Žegura B; Filipič M; Dolenc MS; Perdih A
Bioorg Chem; 2020 Jun; 99():103828. PubMed ID: 32315896
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]