BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

197 related articles for article (PubMed ID: 28389511)

  • 1. Epigenetic Regulation of KPC1 Ubiquitin Ligase Affects the NF-κB Pathway in Melanoma.
    Iida Y; Ciechanover A; Marzese DM; Hata K; Bustos M; Ono S; Wang J; Salomon MP; Tran K; Lam S; Hsu S; Nelson N; Kravtsova-Ivantsiv Y; Mills GB; Davies MA; Hoon DSB
    Clin Cancer Res; 2017 Aug; 23(16):4831-4842. PubMed ID: 28389511
    [No Abstract]   [Full Text] [Related]  

  • 2. A short binding site in the KPC1 ubiquitin ligase mediates processing of NF-κB1 p105 to p50: A potential for a tumor-suppressive PROTAC.
    Goldhirsh G; Kravtsova-Ivantsiv Y; Satish G; Ziv T; Brik A; Ciechanover A
    Proc Natl Acad Sci U S A; 2021 Dec; 118(49):. PubMed ID: 34873064
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Tumor Suppressor Functions of Ubiquitin Ligase KPC1: From Cell-Cycle Control to NF-κB Regulator.
    Gulei D; Drula R; Ghiaur G; Buzoianu AD; Kravtsova-Ivantsiv Y; Tomuleasa C; Ciechanover A
    Cancer Res; 2023 Jun; 83(11):1762-1767. PubMed ID: 36880841
    [TBL] [Abstract][Full Text] [Related]  

  • 4. RASSF8 regulates progression of cutaneous melanoma through nuclear factor-κb.
    Wang J; Hua W; Huang SK; Fan K; Takeshima L; Mao Y; Hoon DS
    Oncotarget; 2015 Oct; 6(30):30165-77. PubMed ID: 26334503
    [TBL] [Abstract][Full Text] [Related]  

  • 5. KPC1-mediated ubiquitination and proteasomal processing of NF-κB1 p105 to p50 restricts tumor growth.
    Kravtsova-Ivantsiv Y; Shomer I; Cohen-Kaplan V; Snijder B; Superti-Furga G; Gonen H; Sommer T; Ziv T; Admon A; Naroditsky I; Jbara M; Brik A; Pikarsky E; Kwon YT; Doweck I; Ciechanover A
    Cell; 2015 Apr; 161(2):333-47. PubMed ID: 25860612
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Epigenetic silencing of miR-708 enhances NF-κB signaling in chronic lymphocytic leukemia.
    Baer C; Oakes CC; Ruppert AS; Claus R; Kim-Wanner SZ; Mertens D; Zenz T; Stilgenbauer S; Byrd JC; Plass C
    Int J Cancer; 2015 Sep; 137(6):1352-61. PubMed ID: 25704289
    [TBL] [Abstract][Full Text] [Related]  

  • 7. MiR-377 targets E2F3 and alters the NF-kB signaling pathway through MAP3K7 in malignant melanoma.
    Zehavi L; Schayek H; Jacob-Hirsch J; Sidi Y; Leibowitz-Amit R; Avni D
    Mol Cancer; 2015 Mar; 14():68. PubMed ID: 25889255
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hmgb1 inhibits Klotho expression and malignant phenotype in melanoma cells by activating NF-κB.
    Xie B; Cao K; Li J; Chen J; Tang J; Chen X; Xia K; Zhou X; Cheng Y; Zhou J; Xie H
    Oncotarget; 2016 Dec; 7(49):80765-80782. PubMed ID: 27779100
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The ubiquitin-proteasome system and activation of NF-κB: involvement of the ubiquitin ligase KPC1 in p105 processing and tumor suppression.
    Kravtsova-Ivantsiv Y; Ciechanover A
    Mol Cell Oncol; 2015; 2(4):e1054552. PubMed ID: 27308511
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Epigallocatechin-3-gallate(EGCG) suppresses melanoma cell growth and metastasis by targeting TRAF6 activity.
    Zhang J; Lei Z; Huang Z; Zhang X; Zhou Y; Luo Z; Zeng W; Su J; Peng C; Chen X
    Oncotarget; 2016 Nov; 7(48):79557-79571. PubMed ID: 27791197
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The A-to-I editing of KPC1 promotes intrahepatic cholangiocarcinoma by attenuating proteasomal processing of NF-κB1 p105 to p50.
    Gao C; Zhou G; Shi J; Shi P; Jin L; Li Y; Wang X; Liao S; Yan H; Wu J; Lu Y; Zhai Y; Zhang J; Zhang H; Zhang H; Yang C; Cao P; Cheng S; Zhou G
    J Exp Clin Cancer Res; 2022 Dec; 41(1):338. PubMed ID: 36476255
    [TBL] [Abstract][Full Text] [Related]  

  • 12. MicroRNA-9 up-regulates E-cadherin through inhibition of NF-κB1-Snail1 pathway in melanoma.
    Liu S; Kumar SM; Lu H; Liu A; Yang R; Pushparajan A; Guo W; Xu X
    J Pathol; 2012 Jan; 226(1):61-72. PubMed ID: 22131135
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MicroRNA-21 regulates the ERK/NF-κB signaling pathway to affect the proliferation, migration, and apoptosis of human melanoma A375 cells by targeting SPRY1, PDCD4, and PTEN.
    Mao XH; Chen M; Wang Y; Cui PG; Liu SB; Xu ZY
    Mol Carcinog; 2017 Mar; 56(3):886-894. PubMed ID: 27533779
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CHIP/Stub1 functions as a tumor suppressor and represses NF-κB-mediated signaling in colorectal cancer.
    Wang Y; Ren F; Wang Y; Feng Y; Wang D; Jia B; Qiu Y; Wang S; Yu J; Sung JJ; Xu J; Zeps N; Chang Z
    Carcinogenesis; 2014 May; 35(5):983-91. PubMed ID: 24302614
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A DNA methylation prognostic signature of glioblastoma: identification of NPTX2-PTEN-NF-κB nexus.
    Shukla S; Pia Patric IR; Thinagararjan S; Srinivasan S; Mondal B; Hegde AS; Chandramouli BA; Santosh V; Arivazhagan A; Somasundaram K
    Cancer Res; 2013 Nov; 73(22):6563-73. PubMed ID: 24078801
    [TBL] [Abstract][Full Text] [Related]  

  • 16. MicroRNA-9 suppresses uveal melanoma cell migration and invasion through the NF-κB1 pathway.
    Liu N; Sun Q; Chen J; Li J; Zeng Y; Zhai S; Li P; Wang B; Wang X
    Oncol Rep; 2012 Sep; 28(3):961-8. PubMed ID: 22825752
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A negative feedback loop between miR-200b and the nuclear factor-κB pathway via IKBKB/IKK-β in breast cancer cells.
    Wu H; Wang G; Wang Z; An S; Ye P; Luo S
    FEBS J; 2016 Jun; 283(12):2259-71. PubMed ID: 26433127
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Prognostic relevance of miRNA-155 methylation in anaplastic glioma.
    Schliesser MG; Claus R; Hielscher T; Grimm C; Weichenhan D; Blaes J; Wiestler B; Hau P; Schramm J; Sahm F; Weiß EK; Weiler M; Baer C; Schmidt-Graf F; Schackert G; Westphal M; Hertenstein A; Roth P; Galldiks N; Hartmann C; Pietsch T; Felsberg J; Reifenberger G; Sabel MC; Winkler F; von Deimling A; Meisner C; Vajkoczy P; Platten M; Weller M; Plass C; Wick W
    Oncotarget; 2016 Dec; 7(50):82028-82045. PubMed ID: 27880937
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Excess of the NF-ĸB p50 subunit generated by the ubiquitin ligase KPC1 suppresses tumors via PD-L1- and chemokines-mediated mechanisms.
    Kravtsova-Ivantsiv Y; Goldhirsh G; Ivantsiv A; Ben Itzhak O; Kwon YT; Pikarsky E; Ciechanover A
    Proc Natl Acad Sci U S A; 2020 Nov; 117(47):29823-29831. PubMed ID: 33168738
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A20 inhibits both the degradation and limited processing of the NF-κB p105 precursor: A novel additional layer to its regulator role.
    Lapid D; Lahav-Baratz S; Cohen S
    Biochem Biophys Res Commun; 2017 Nov; 493(1):52-57. PubMed ID: 28923245
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.