BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

393 related articles for article (PubMed ID: 28390177)

  • 1. Role of the Lysosomal Membrane Protein, CLN3, in the Regulation of Cathepsin D Activity.
    Cárcel-Trullols J; Kovács AD; Pearce DA
    J Cell Biochem; 2017 Nov; 118(11):3883-3890. PubMed ID: 28390177
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cln3-mutations underlying juvenile neuronal ceroid lipofuscinosis cause significantly reduced levels of Palmitoyl-protein thioesterases-1 (Ppt1)-protein and Ppt1-enzyme activity in the lysosome.
    Appu AP; Bagh MB; Sadhukhan T; Mondal A; Casey S; Mukherjee AB
    J Inherit Metab Dis; 2019 Sep; 42(5):944-954. PubMed ID: 31025705
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CLN3 protein regulates lysosomal pH and alters intracellular processing of Alzheimer's amyloid-beta protein precursor and cathepsin D in human cells.
    Golabek AA; Kida E; Walus M; Kaczmarski W; Michalewski M; Wisniewski KE
    Mol Genet Metab; 2000 Jul; 70(3):203-13. PubMed ID: 10924275
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Defective lysosomal arginine transport in juvenile Batten disease.
    Ramirez-Montealegre D; Pearce DA
    Hum Mol Genet; 2005 Dec; 14(23):3759-73. PubMed ID: 16251196
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Osmotic stress changes the expression and subcellular localization of the Batten disease protein CLN3.
    Getty A; Kovács AD; Lengyel-Nelson T; Cardillo A; Hof C; Chan CH; Pearce DA
    PLoS One; 2013; 8(6):e66203. PubMed ID: 23840424
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A function retained by the common mutant CLN3 protein is responsible for the late onset of juvenile neuronal ceroid lipofuscinosis.
    Kitzmüller C; Haines RL; Codlin S; Cutler DF; Mole SE
    Hum Mol Genet; 2008 Jan; 17(2):303-12. PubMed ID: 17947292
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Membrane trafficking and mitochondrial abnormalities precede subunit c deposition in a cerebellar cell model of juvenile neuronal ceroid lipofuscinosis.
    Fossale E; Wolf P; Espinola JA; Lubicz-Nawrocka T; Teed AM; Gao H; Rigamonti D; Cattaneo E; MacDonald ME; Cotman SL
    BMC Neurosci; 2004 Dec; 5():57. PubMed ID: 15588329
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enzyme replacement therapy with recombinant pro-CTSD (cathepsin D) corrects defective proteolysis and autophagy in neuronal ceroid lipofuscinosis.
    Marques ARA; Di Spiezio A; Thießen N; Schmidt L; Grötzinger J; Lüllmann-Rauch R; Damme M; Storck SE; Pietrzik CU; Fogh J; Bär J; Mikhaylova M; Glatzel M; Bassal M; Bartsch U; Saftig P
    Autophagy; 2020 May; 16(5):811-825. PubMed ID: 31282275
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Transcript and in silico analysis of CLN3 in juvenile neuronal ceroid lipofuscinosis and associated mouse models.
    Chan CH; Mitchison HM; Pearce DA
    Hum Mol Genet; 2008 Nov; 17(21):3332-9. PubMed ID: 18678598
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Partial correction of the CNS lysosomal storage defect in a mouse model of juvenile neuronal ceroid lipofuscinosis by neonatal CNS administration of an adeno-associated virus serotype rh.10 vector expressing the human CLN3 gene.
    Sondhi D; Scott EC; Chen A; Hackett NR; Wong AM; Kubiak A; Nelvagal HR; Pearse Y; Cotman SL; Cooper JD; Crystal RG
    Hum Gene Ther; 2014 Mar; 25(3):223-39. PubMed ID: 24372003
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Loss of the Batten disease gene CLN3 prevents exit from the TGN of the mannose 6-phosphate receptor.
    Metcalf DJ; Calvi AA; Seaman MNj; Mitchison HM; Cutler DF
    Traffic; 2008 Nov; 9(11):1905-14. PubMed ID: 18817525
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Revisiting the neuronal localization and trafficking of CLN3 in juvenile neuronal ceroid lipofuscinosis.
    Oetjen S; Kuhl D; Hermey G
    J Neurochem; 2016 Nov; 139(3):456-470. PubMed ID: 27453211
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Converging roles of PSENEN/PEN2 and CLN3 in the autophagy-lysosome system.
    Klein M; Kaleem A; Oetjen S; Wünkhaus D; Binkle L; Schilling S; Gjorgjieva M; Scholz R; Gruber-Schoffnegger D; Storch S; Kins S; Drewes G; Hoffmeister-Ullerich S; Kuhl D; Hermey G
    Autophagy; 2022 Sep; 18(9):2068-2085. PubMed ID: 34964690
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CLN3 is required for the clearance of glycerophosphodiesters from lysosomes.
    Laqtom NN; Dong W; Medoh UN; Cangelosi AL; Dharamdasani V; Chan SH; Kunchok T; Lewis CA; Heinze I; Tang R; Grimm C; Dang Do AN; Porter FD; Ori A; Sabatini DM; Abu-Remaileh M
    Nature; 2022 Sep; 609(7929):1005-1011. PubMed ID: 36131016
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CLN3, at the crossroads of endocytic trafficking.
    Cotman SL; Lefrancois S
    Neurosci Lett; 2021 Sep; 762():136117. PubMed ID: 34274435
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Unbiased Cell-based Screening in a Neuronal Cell Model of Batten Disease Highlights an Interaction between Ca2+ Homeostasis, Autophagy, and CLN3 Protein Function.
    Chandrachud U; Walker MW; Simas AM; Heetveld S; Petcherski A; Klein M; Oh H; Wolf P; Zhao WN; Norton S; Haggarty SJ; Lloyd-Evans E; Cotman SL
    J Biol Chem; 2015 Jun; 290(23):14361-80. PubMed ID: 25878248
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Self-Complementary AAV9 Gene Delivery Partially Corrects Pathology Associated with Juvenile Neuronal Ceroid Lipofuscinosis (CLN3).
    Bosch ME; Aldrich A; Fallet R; Odvody J; Burkovetskaya M; Schuberth K; Fitzgerald JA; Foust KD; Kielian T
    J Neurosci; 2016 Sep; 36(37):9669-82. PubMed ID: 27629717
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The CLN3 gene and protein: What we know.
    Mirza M; Vainshtein A; DiRonza A; Chandrachud U; Haslett LJ; Palmieri M; Storch S; Groh J; Dobzinski N; Napolitano G; Schmidtke C; Kerkovich DM
    Mol Genet Genomic Med; 2019 Dec; 7(12):e859. PubMed ID: 31568712
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Neuronal ceroid lipofuscinosis protein CLN3 interacts with motor proteins and modifies location of late endosomal compartments.
    Uusi-Rauva K; Kyttälä A; van der Kant R; Vesa J; Tanhuanpää K; Neefjes J; Olkkonen VM; Jalanko A
    Cell Mol Life Sci; 2012 Jun; 69(12):2075-89. PubMed ID: 22261744
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Loss of CLN3, the gene mutated in juvenile neuronal ceroid lipofuscinosis, leads to metabolic impairment and autophagy induction in retinal pigment epithelium.
    Zhong Y; Mohan K; Liu J; Al-Attar A; Lin P; Flight RM; Sun Q; Warmoes MO; Deshpande RR; Liu H; Jung KS; Mitov MI; Lin N; Butterfield DA; Lu S; Liu J; Moseley HNB; Fan TWM; Kleinman ME; Wang QJ
    Biochim Biophys Acta Mol Basis Dis; 2020 Oct; 1866(10):165883. PubMed ID: 32592935
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.