BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

185 related articles for article (PubMed ID: 28390897)

  • 1. Identification and characterization of two novel PTCH1 splice variants.
    Yu P; Yang J; Zhang Y
    Biochem Biophys Res Commun; 2017 May; 487(1):68-75. PubMed ID: 28390897
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Distinct roles of first exon variants of the tumor-suppressor Patched1 in Hedgehog signaling.
    Shimokawa T; Svärd J; Heby-Henricson K; Teglund S; Toftgård R; Zaphiropoulos PG
    Oncogene; 2007 Jul; 26(34):4889-96. PubMed ID: 17310997
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Distinct roles of PTCH2 splice variants in Hedgehog signalling.
    Rahnama F; Toftgård R; Zaphiropoulos PG
    Biochem J; 2004 Mar; 378(Pt 2):325-34. PubMed ID: 14613484
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activities of the Cytoplasmic Domains of Patched-1 Modulate but Are Not Essential for the Regulation of Canonical Hedgehog Signaling.
    Fleet A; Lee JP; Tamachi A; Javeed I; Hamel PA
    J Biol Chem; 2016 Aug; 291(34):17557-68. PubMed ID: 27325696
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The protein-specific activities of the transmembrane modules of Ptch1 and Ptch2 are determined by their adjacent protein domains.
    Fleet AJ; Hamel PA
    J Biol Chem; 2018 Oct; 293(43):16583-16595. PubMed ID: 30166346
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hedgehog Signaling and Truncated GLI1 in Cancer.
    Doheny D; Manore SG; Wong GL; Lo HW
    Cells; 2020 Sep; 9(9):. PubMed ID: 32957513
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The hedgehog-patched signaling pathway and function in the mammalian ovary: a novel role for hedgehog proteins in stimulating proliferation and steroidogenesis of theca cells.
    Spicer LJ; Sudo S; Aad PY; Wang LS; Chun SY; Ben-Shlomo I; Klein C; Hsueh AJ
    Reproduction; 2009 Aug; 138(2):329-39. PubMed ID: 19433502
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hedgehog-signaling is upregulated in non-producing human adrenal adenomas and antagonism of hedgehog-signaling inhibits proliferation of NCI-H295R cells and an immortalized primary human adrenal cell line.
    Werminghaus P; Haase M; Hornsby PJ; Schinner S; Schott M; Malendowicz LK; Lammers BJ; Goretzki PE; Müller-Mattheis V; Markus Giessing ; Willenberg HS
    J Steroid Biochem Mol Biol; 2014 Jan; 139():7-15. PubMed ID: 24063979
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structures of human Patched and its complex with native palmitoylated sonic hedgehog.
    Qi X; Schmiege P; Coutavas E; Wang J; Li X
    Nature; 2018 Aug; 560(7716):128-132. PubMed ID: 29995851
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Patched1 and Patched2 inhibit Smoothened non-cell autonomously.
    Roberts B; Casillas C; Alfaro AC; Jägers C; Roelink H
    Elife; 2016 Aug; 5():. PubMed ID: 27552050
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Repression of smoothened by patched-dependent (pro-)vitamin D3 secretion.
    Bijlsma MF; Spek CA; Zivkovic D; van de Water S; Rezaee F; Peppelenbosch MP
    PLoS Biol; 2006 Jul; 4(8):e232. PubMed ID: 16895439
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A Novel Mechanism for Activation of GLI1 by Nuclear SMO That Escapes Anti-SMO Inhibitors.
    Rahman MM; Hazan A; Selway JL; Herath DS; Harwood CA; Pirzado MS; Atkar R; Kelsell DP; Linton KJ; Philpott MP; Neill GW
    Cancer Res; 2018 May; 78(10):2577-2588. PubMed ID: 29463581
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Expression of the PTCH1 tumor suppressor gene is regulated by alternative promoters and a single functional Gli-binding site.
    Agren M; Kogerman P; Kleman MI; Wessling M; Toftgård R
    Gene; 2004 Apr; 330():101-14. PubMed ID: 15087129
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Expression, Purification, and Structure Determination of Human PTCH1-HH-N Complexes.
    Qi X; Schmiege P; Esparza L; Li X
    Methods Mol Biol; 2022; 2374():107-120. PubMed ID: 34562247
    [TBL] [Abstract][Full Text] [Related]  

  • 15. All-trans-retinoic acid antagonizes the Hedgehog pathway by inducing patched.
    Busch AM; Galimberti F; Nehls KE; Roengvoraphoj M; Sekula D; Li B; Guo Y; Direnzo J; Fiering SN; Spinella MJ; Robbins DJ; Memoli VA; Freemantle SJ; Dmitrovsky E
    Cancer Biol Ther; 2014 Apr; 15(4):463-72. PubMed ID: 24496080
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Patched-2 functions to limit Patched-1 deficient skin cancer growth.
    Veenstra VL; Dingjan I; Waasdorp C; Damhofer H; van der Wal AC; van Laarhoven HW; Medema JP; Bijlsma MF
    Cell Oncol (Dordr); 2018 Aug; 41(4):427-437. PubMed ID: 29869097
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Loss of the PTCH1 tumor suppressor defines a new subset of plexiform fibromyxoma.
    Banerjee S; Corless CL; Miettinen MM; Noh S; Ustoy R; Davis JL; Tang CM; Yebra M; Burgoyne AM; Sicklick JK
    J Transl Med; 2019 Jul; 17(1):246. PubMed ID: 31362756
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ptch2 mediates the Shh response in Ptch1-/- cells.
    Alfaro AC; Roberts B; Kwong L; Bijlsma MF; Roelink H
    Development; 2014 Sep; 141(17):3331-9. PubMed ID: 25085974
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Trisomy 12 and elevated GLI1 and PTCH1 transcript levels are biomarkers for Hedgehog-inhibitor responsiveness in CLL.
    Decker S; Zirlik K; Djebatchie L; Hartmann D; Ihorst G; Schmitt-Graeff A; Herchenbach D; Jumaa H; Warmuth M; Veelken H; Dierks C
    Blood; 2012 Jan; 119(4):997-1007. PubMed ID: 22130798
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Activation of Erk by sonic hedgehog independent of canonical hedgehog signalling.
    Chang H; Li Q; Moraes RC; Lewis MT; Hamel PA
    Int J Biochem Cell Biol; 2010 Sep; 42(9):1462-71. PubMed ID: 20451654
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.