BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

303 related articles for article (PubMed ID: 28393832)

  • 41. TRF2-tethered TIN2 can mediate telomere protection by TPP1/POT1.
    Frescas D; de Lange T
    Mol Cell Biol; 2014 Apr; 34(7):1349-62. PubMed ID: 24469404
    [TBL] [Abstract][Full Text] [Related]  

  • 42. G-quadruplex formation in telomeres enhances POT1/TPP1 protection against RPA binding.
    Ray S; Bandaria JN; Qureshi MH; Yildiz A; Balci H
    Proc Natl Acad Sci U S A; 2014 Feb; 111(8):2990-5. PubMed ID: 24516170
    [TBL] [Abstract][Full Text] [Related]  

  • 43. How telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNA.
    Nandakumar J; Podell ER; Cech TR
    Proc Natl Acad Sci U S A; 2010 Jan; 107(2):651-6. PubMed ID: 20080730
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Identification of human TERT elements necessary for telomerase recruitment to telomeres.
    Schmidt JC; Dalby AB; Cech TR
    Elife; 2014 Oct; 3():. PubMed ID: 25271372
    [TBL] [Abstract][Full Text] [Related]  

  • 45. POT1-TPP1 telomere length regulation and disease.
    Aramburu T; Plucinsky S; Skordalakes E
    Comput Struct Biotechnol J; 2020; 18():1939-1946. PubMed ID: 32774788
    [TBL] [Abstract][Full Text] [Related]  

  • 46. POT1-TPP1 enhances telomerase processivity by slowing primer dissociation and aiding translocation.
    Latrick CM; Cech TR
    EMBO J; 2010 Mar; 29(5):924-33. PubMed ID: 20094033
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Shelterin: the protein complex that shapes and safeguards human telomeres.
    de Lange T
    Genes Dev; 2005 Sep; 19(18):2100-10. PubMed ID: 16166375
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Distinct functions of POT1 proteins contribute to the regulation of telomerase recruitment to telomeres.
    Gu P; Jia S; Takasugi T; Tesmer VM; Nandakumar J; Chen Y; Chang S
    Nat Commun; 2021 Sep; 12(1):5514. PubMed ID: 34535663
    [TBL] [Abstract][Full Text] [Related]  

  • 49. The Replisome Mediates A-NHEJ Repair of Telomeres Lacking POT1-TPP1 Independently of MRN Function.
    Rai R; Gu P; Broton C; Kumar-Sinha C; Chen Y; Chang S
    Cell Rep; 2019 Dec; 29(11):3708-3725.e5. PubMed ID: 31825846
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Reconstitution of human shelterin complexes reveals unexpected stoichiometry and dual pathways to enhance telomerase processivity.
    Lim CJ; Zaug AJ; Kim HJ; Cech TR
    Nat Commun; 2017 Oct; 8(1):1075. PubMed ID: 29057866
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Dysfunctional telomeres activate an ATM-ATR-dependent DNA damage response to suppress tumorigenesis.
    Guo X; Deng Y; Lin Y; Cosme-Blanco W; Chan S; He H; Yuan G; Brown EJ; Chang S
    EMBO J; 2007 Nov; 26(22):4709-19. PubMed ID: 17948054
    [TBL] [Abstract][Full Text] [Related]  

  • 52. POT1 mutations cause differential effects on telomere length leading to opposing disease phenotypes.
    Zade NH; Khattar E
    J Cell Physiol; 2023 Jun; 238(6):1237-1255. PubMed ID: 37183325
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Specificity requirements for human telomere protein interaction with telomerase holoenzyme.
    Sexton AN; Youmans DT; Collins K
    J Biol Chem; 2012 Oct; 287(41):34455-64. PubMed ID: 22893708
    [TBL] [Abstract][Full Text] [Related]  

  • 54. The enigma of excessively long telomeres in cancer: lessons learned from rare human POT1 variants.
    Gong Y; Stock AJ; Liu Y
    Curr Opin Genet Dev; 2020 Feb; 60():48-55. PubMed ID: 32155570
    [TBL] [Abstract][Full Text] [Related]  

  • 55. OB fold-containing protein 1 (OBFC1), a human homolog of yeast Stn1, associates with TPP1 and is implicated in telomere length regulation.
    Wan M; Qin J; Songyang Z; Liu D
    J Biol Chem; 2009 Sep; 284(39):26725-31. PubMed ID: 19648609
    [TBL] [Abstract][Full Text] [Related]  

  • 56. TPP1 OB-fold domain protein suppresses cell proliferation and induces cell apoptosis by inhibiting telomerase recruitment to telomeres in human lung cancer cells.
    Zhu J; Liu W; Chen C; Zhang H; Yue D; Li C; Zhang L; Gao L; Huo Y; Liu C; Giaccone G; Zhang B; Wang C
    J Cancer Res Clin Oncol; 2019 Jun; 145(6):1509-1519. PubMed ID: 31016380
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Protection of telomeres by a conserved Stn1-Ten1 complex.
    Martín V; Du LL; Rozenzhak S; Russell P
    Proc Natl Acad Sci U S A; 2007 Aug; 104(35):14038-43. PubMed ID: 17715303
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Interaction hub critical for telomerase recruitment and primer-template handling for catalysis.
    Padmanaban S; Tesmer VM; Nandakumar J
    Life Sci Alliance; 2023 Jun; 6(6):. PubMed ID: 36963832
    [TBL] [Abstract][Full Text] [Related]  

  • 59. PTOP interacts with POT1 and regulates its localization to telomeres.
    Liu D; Safari A; O'Connor MS; Chan DW; Laegeler A; Qin J; Songyang Z
    Nat Cell Biol; 2004 Jul; 6(7):673-80. PubMed ID: 15181449
    [TBL] [Abstract][Full Text] [Related]  

  • 60. The intrinsically disordered N-terminal region of mouse DNA polymerase alpha mediates its interaction with POT1a/b at telomeres.
    Mizuno T; Hirabayashi K; Miyazawa S; Kobayashi Y; Shoji K; Kobayashi M; Hanaoka F; Imamoto N; Torigoe H
    Genes Cells; 2021 Jun; 26(6):360-380. PubMed ID: 33711210
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 16.