325 related articles for article (PubMed ID: 28396345)
1. The WW domain of the scaffolding protein IQGAP1 is neither necessary nor sufficient for binding to the MAPKs ERK1 and ERK2.
Bardwell AJ; Lagunes L; Zebarjedi R; Bardwell L
J Biol Chem; 2017 May; 292(21):8750-8761. PubMed ID: 28396345
[TBL] [Abstract][Full Text] [Related]
2. IQGAP1 is a scaffold for mitogen-activated protein kinase signaling.
Roy M; Li Z; Sacks DB
Mol Cell Biol; 2005 Sep; 25(18):7940-52. PubMed ID: 16135787
[TBL] [Abstract][Full Text] [Related]
3. IQGAP1 regulates ERK1/2 and AKT signalling in the heart and sustains functional remodelling upon pressure overload.
Sbroggiò M; Carnevale D; Bertero A; Cifelli G; De Blasio E; Mascio G; Hirsch E; Bahou WF; Turco E; Silengo L; Brancaccio M; Lembo G; Tarone G
Cardiovasc Res; 2011 Aug; 91(3):456-64. PubMed ID: 21493702
[TBL] [Abstract][Full Text] [Related]
4. IQGAP1 scaffold-kinase interaction blockade selectively targets RAS-MAP kinase-driven tumors.
Jameson KL; Mazur PK; Zehnder AM; Zhang J; Zarnegar B; Sage J; Khavari PA
Nat Med; 2013 May; 19(5):626-630. PubMed ID: 23603816
[TBL] [Abstract][Full Text] [Related]
5. IQGAP1 binds ERK2 and modulates its activity.
Roy M; Li Z; Sacks DB
J Biol Chem; 2004 Apr; 279(17):17329-37. PubMed ID: 14970219
[TBL] [Abstract][Full Text] [Related]
6. Quercetin suppresses the proliferation of multiple myeloma cells by down-regulating IQ motif-containing GTPase activating protein 1 expression and extracellular signal-regulated kinase activation.
Ma Y; Jin Z; Huang J; Zhou S; Ye H; Jiang S; Yu K
Leuk Lymphoma; 2014 Nov; 55(11):2597-604. PubMed ID: 24397597
[TBL] [Abstract][Full Text] [Related]
7. Docking sites on mitogen-activated protein kinase (MAPK) kinases, MAPK phosphatases and the Elk-1 transcription factor compete for MAPK binding and are crucial for enzymic activity.
Bardwell AJ; Abdollahi M; Bardwell L
Biochem J; 2003 Mar; 370(Pt 3):1077-85. PubMed ID: 12529172
[TBL] [Abstract][Full Text] [Related]
8. RNAi-mediated MEK1 knock-down prevents ERK1/2 activation and abolishes human hepatocarcinoma growth in vitro and in vivo.
Gailhouste L; Ezan F; Bessard A; Frémin C; Rageul J; Langouët S; Baffet G
Int J Cancer; 2010 Mar; 126(6):1367-77. PubMed ID: 19816936
[TBL] [Abstract][Full Text] [Related]
9. MAP kinase: it's been longer than fifteen minutes.
Sturgill TW
Biochem Biophys Res Commun; 2008 Jun; 371(1):1-4. PubMed ID: 18406346
[TBL] [Abstract][Full Text] [Related]
10. Hierarchical scaffolding of an ERK1/2 activation pathway.
Vetterkind S; Poythress RH; Lin QQ; Morgan KG
Cell Commun Signal; 2013 Aug; 11():65. PubMed ID: 23987506
[TBL] [Abstract][Full Text] [Related]
11. Mitogen-activated protein kinase (MAPK)-docking sites in MAPK kinases function as tethers that are crucial for MAPK regulation in vivo.
Grewal S; Molina DM; Bardwell L
Cell Signal; 2006 Jan; 18(1):123-34. PubMed ID: 15979847
[TBL] [Abstract][Full Text] [Related]
12. S100P is a novel interaction partner and regulator of IQGAP1.
Heil A; Nazmi AR; Koltzscher M; Poeter M; Austermann J; Assard N; Baudier J; Kaibuchi K; Gerke V
J Biol Chem; 2011 Mar; 286(9):7227-38. PubMed ID: 21177863
[TBL] [Abstract][Full Text] [Related]
13. A novel mechanism of ERK1/2 regulation in smooth muscle involving acetylation of the ERK1/2 scaffold IQGAP1.
Vetterkind S; Lin QQ; Morgan KG
Sci Rep; 2017 Aug; 7(1):9302. PubMed ID: 28839270
[TBL] [Abstract][Full Text] [Related]
14. A conserved docking site in MEKs mediates high-affinity binding to MAP kinases and cooperates with a scaffold protein to enhance signal transmission.
Bardwell AJ; Flatauer LJ; Matsukuma K; Thorner J; Bardwell L
J Biol Chem; 2001 Mar; 276(13):10374-86. PubMed ID: 11134045
[TBL] [Abstract][Full Text] [Related]
15. Salmonella enterica serotype Typhimurium usurps the scaffold protein IQGAP1 to manipulate Rac1 and MAPK signalling.
Kim H; White CD; Li Z; Sacks DB
Biochem J; 2011 Dec; 440(3):309-18. PubMed ID: 21851337
[TBL] [Abstract][Full Text] [Related]
16. Extracellular signal-regulated kinase 2 (ERK2) phosphorylation sites and docking domain on the nuclear pore complex protein Tpr cooperatively regulate ERK2-Tpr interaction.
Vomastek T; Iwanicki MP; Burack WR; Tiwari D; Kumar D; Parsons JT; Weber MJ; Nandicoori VK
Mol Cell Biol; 2008 Nov; 28(22):6954-66. PubMed ID: 18794356
[TBL] [Abstract][Full Text] [Related]
17. The WW domain of IQGAP1 binds directly to the p110α catalytic subunit of PI 3-kinase.
Bardwell AJ; Paul M; Yoneda KC; Andrade-Ludeña MD; Nguyen OT; Fruman D; Bardwell L
Biochem J; 2023 May; ():. PubMed ID: 37145016
[TBL] [Abstract][Full Text] [Related]
18. IQGAP1 mediates angiotensin II-induced apoptosis of podocytes via the ERK1/2 MAPK signaling pathway.
Liu Y; Liang W; Yang Q; Ren Z; Chen X; Zha D; Singhal PC; Ding G
Am J Nephrol; 2013; 38(5):430-44. PubMed ID: 24247724
[TBL] [Abstract][Full Text] [Related]
19. Identification of novel point mutations in ERK2 that selectively disrupt binding to MEK1.
Robinson FL; Whitehurst AW; Raman M; Cobb MH
J Biol Chem; 2002 Apr; 277(17):14844-52. PubMed ID: 11823456
[TBL] [Abstract][Full Text] [Related]
20. Hyaluronan-CD44 interaction with IQGAP1 promotes Cdc42 and ERK signaling, leading to actin binding, Elk-1/estrogen receptor transcriptional activation, and ovarian cancer progression.
Bourguignon LY; Gilad E; Rothman K; Peyrollier K
J Biol Chem; 2005 Mar; 280(12):11961-72. PubMed ID: 15655247
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
