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5. Heterozygous deletion of the autism-associated gene CHD8 impairs synaptic function through widespread changes in gene expression and chromatin compaction. Shi X; Lu C; Corman A; Nikish A; Zhou Y; Platt RJ; Iossifov I; Zhang F; Pan JQ; Sanjana NE Am J Hum Genet; 2023 Oct; 110(10):1750-1768. PubMed ID: 37802044 [TBL] [Abstract][Full Text] [Related]
6. CHD8 regulates neurodevelopmental pathways associated with autism spectrum disorder in neural progenitors. Sugathan A; Biagioli M; Golzio C; Erdin S; Blumenthal I; Manavalan P; Ragavendran A; Brand H; Lucente D; Miles J; Sheridan SD; Stortchevoi A; Kellis M; Haggarty SJ; Katsanis N; Gusella JF; Talkowski ME Proc Natl Acad Sci U S A; 2014 Oct; 111(42):E4468-77. PubMed ID: 25294932 [TBL] [Abstract][Full Text] [Related]
7. CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in cerebral organoids derived from iPS cells. Wang P; Mokhtari R; Pedrosa E; Kirschenbaum M; Bayrak C; Zheng D; Lachman HM Mol Autism; 2017; 8():11. PubMed ID: 28321286 [TBL] [Abstract][Full Text] [Related]
8. CHD8 intragenic deletion associated with autism spectrum disorder. Stolerman ES; Smith B; Chaubey A; Jones JR Eur J Med Genet; 2016 Apr; 59(4):189-94. PubMed ID: 26921529 [TBL] [Abstract][Full Text] [Related]
9. CHD8 haploinsufficiency links autism to transient alterations in excitatory and inhibitory trajectories. Villa CE; Cheroni C; Dotter CP; López-Tóbon A; Oliveira B; Sacco R; Yahya AÇ; Morandell J; Gabriele M; Tavakoli MR; Lyudchik J; Sommer C; Gabitto M; Danzl JG; Testa G; Novarino G Cell Rep; 2022 Apr; 39(1):110615. PubMed ID: 35385734 [TBL] [Abstract][Full Text] [Related]
10. Recurrent ∼100 Kb microdeletion in the chromosomal region 14q11.2, involving CHD8 gene, is associated with autism and macrocephaly. Prontera P; Ottaviani V; Toccaceli D; Rogaia D; Ardisia C; Romani R; Stangoni G; Pierini A; Donti E Am J Med Genet A; 2014 Dec; 164A(12):3137-41. PubMed ID: 25257502 [TBL] [Abstract][Full Text] [Related]
11. The autism-associated chromatin modifier CHD8 regulates other autism risk genes during human neurodevelopment. Cotney J; Muhle RA; Sanders SJ; Liu L; Willsey AJ; Niu W; Liu W; Klei L; Lei J; Yin J; Reilly SK; Tebbenkamp AT; Bichsel C; Pletikos M; Sestan N; Roeder K; State MW; Devlin B; Noonan JP Nat Commun; 2015 Mar; 6():6404. PubMed ID: 25752243 [TBL] [Abstract][Full Text] [Related]
12. The complex etiology of autism spectrum disorder due to missense mutations of CHD8. Shiraishi T; Katayama Y; Nishiyama M; Shoji H; Miyakawa T; Mizoo T; Matsumoto A; Hijikata A; Shirai T; Mayanagi K; Nakayama KI Mol Psychiatry; 2024 Jul; 29(7):2145-2160. PubMed ID: 38438524 [TBL] [Abstract][Full Text] [Related]
14. The phenotypic spectrum and genotype-phenotype correlations in 106 patients with variants in major autism gene CHD8. Dingemans AJM; Truijen KMG; van de Ven S; Bernier R; Bongers EMHF; Bouman A; de Graaff-Herder L; Eichler EE; Gerkes EH; De Geus CM; van Hagen JM; Jansen PR; Kerkhof J; Kievit AJA; Kleefstra T; Maas SM; de Man SA; McConkey H; Patterson WG; Dobson AT; Prijoles EJ; Sadikovic B; Relator R; Stevenson RE; Stumpel CTRM; Heijligers M; Stuurman KE; Löhner K; Zeidler S; Lee JA; Lindy A; Zou F; Tedder ML; Vissers LELM; de Vries BBA Transl Psychiatry; 2022 Oct; 12(1):421. PubMed ID: 36182950 [TBL] [Abstract][Full Text] [Related]
15. Autism-associated CHD8 keeps proliferation of human neural progenitors in check by lengthening the G1 phase of the cell cycle. Coakley-Youngs E; Ranatunga M; Richardson S; Getti G; Shorter S; Fivaz M Biol Open; 2022 Sep; 11(9):. PubMed ID: 36222238 [TBL] [Abstract][Full Text] [Related]
16. Autism spectrum disorder early in development associated with CHD8 mutations among two Chinese children. Wang J; Liu J; Gao Y; Wang K; Jiang K BMC Pediatr; 2018 Oct; 18(1):338. PubMed ID: 30376831 [TBL] [Abstract][Full Text] [Related]
17. First glimpses of the neurobiology of autism spectrum disorder. Sanders SJ Curr Opin Genet Dev; 2015 Aug; 33():80-92. PubMed ID: 26547130 [TBL] [Abstract][Full Text] [Related]
18. Targeted sequencing and functional analysis reveal brain-size-related genes and their networks in autism spectrum disorders. Li J; Wang L; Guo H; Shi L; Zhang K; Tang M; Hu S; Dong S; Liu Y; Wang T; Yu P; He X; Hu Z; Zhao J; Liu C; Sun ZS; Xia K Mol Psychiatry; 2017 Sep; 22(9):1282-1290. PubMed ID: 28831199 [TBL] [Abstract][Full Text] [Related]
19. A de novo frameshift mutation in chromodomain helicase DNA-binding domain 8 (CHD8): A case report and literature review. Merner N; Forgeot d'Arc B; Bell SC; Maussion G; Peng H; Gauthier J; Crapper L; Hamdan FF; Michaud JL; Mottron L; Rouleau GA; Ernst C Am J Med Genet A; 2016 May; 170A(5):1225-35. PubMed ID: 26789910 [TBL] [Abstract][Full Text] [Related]
20. Autism-associated CHD8 controls reactive gliosis and neuroinflammation via remodeling chromatin in astrocytes. Megagiannis P; Mei Y; Yan RE; Yuan L; Wilde JJ; Eckersberg H; Suresh R; Tan X; Chen H; Farmer WT; Cha K; Le PU; Catoire H; Rochefort D; Kwan T; Yee BA; Dion P; Krishnaswamy A; Cloutier JF; Stifani S; Petrecca K; Yeo GW; Murai KK; Feng G; Rouleau GA; Ideker T; Sanjana NE; Zhou Y Cell Rep; 2024 Aug; 43(8):114637. PubMed ID: 39154337 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]