These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. Quinazoline clubbed 1,3,5-triazine derivatives as VEGFR2 kinase inhibitors: design, synthesis, docking, in vitro cytotoxicity and in ovo antiangiogenic activity. Pathak P; Shukla PK; Kumar V; Kumar A; Verma A Inflammopharmacology; 2018 Dec; 26(6):1441-1453. PubMed ID: 29663100 [TBL] [Abstract][Full Text] [Related]
4. Design, synthesis and biological evaluation of novel 4-anilinoquinazoline derivatives as hypoxia-selective EGFR and VEGFR-2 dual inhibitors. Wei H; Duan Y; Gou W; Cui J; Ning H; Li D; Qin Y; Liu Q; Li Y Eur J Med Chem; 2019 Nov; 181():111552. PubMed ID: 31387063 [TBL] [Abstract][Full Text] [Related]
5. Antiproliferative and Antiangiogenic Properties of New VEGFR-2-targeting 2-thioxobenzo[ Abuelizz HA; Marzouk M; Bakheit AH; Awad HM; Soltan MM; Naglah AM; Al-Salahi R Molecules; 2020 Dec; 25(24):. PubMed ID: 33333992 [TBL] [Abstract][Full Text] [Related]
6. Synthesis, Molecular Modeling and Biological Evaluation of 4-Alkoxyquinazoline Derivatives as Novel Inhibitors of VEGFR2. Lu L; Zhao TT; Liu TB; Sun WX; Xu C; Li DD; Zhu HL Chem Pharm Bull (Tokyo); 2016 Nov; 64(11):1570-1575. PubMed ID: 27568484 [TBL] [Abstract][Full Text] [Related]
7. Discovery of novel VEGFR-2 inhibitors embedding 6,7-dimethoxyquinazoline and diarylamide fragments. Wang R; Liu H; You YY; Wang XY; Lv BB; Cao LQ; Xue JY; Xu YG; Shi L Bioorg Med Chem Lett; 2021 Mar; 36():127788. PubMed ID: 33460739 [TBL] [Abstract][Full Text] [Related]
8. Novel 2-chloro-4-anilino-quinazoline derivatives as EGFR and VEGFR-2 dual inhibitors. Barbosa ML; Lima LM; Tesch R; Sant'Anna CM; Totzke F; Kubbutat MH; Schächtele C; Laufer SA; Barreiro EJ Eur J Med Chem; 2014 Jan; 71():1-14. PubMed ID: 24269511 [TBL] [Abstract][Full Text] [Related]
9. Novel promising 4-anilinoquinazoline-based derivatives as multi-target RTKs inhibitors: Design, molecular docking, synthesis, and antitumor activities in vitro and vivo. Xu P; Chu J; Li Y; Wang Y; He Y; Qi C; Chang J Bioorg Med Chem; 2019 Oct; 27(20):114938. PubMed ID: 31488358 [TBL] [Abstract][Full Text] [Related]
10. Discovery of Dioxino[2,3-f]quinazoline derivative VEGFR-2 inhibitors exerting significant antipro-liferative activity in HUVECs and mice. Fan H; Wei D; Zheng K; Qin X; Yang L; Yang Y; Duan Y; Xu Y; Hu L Eur J Med Chem; 2019 Aug; 175():349-356. PubMed ID: 31096155 [TBL] [Abstract][Full Text] [Related]
12. Synthesis and antitumor activities evaluation of m-(4-morpholinoquinazolin-2-yl)benzamides in vitro and in vivo. Wang XM; Xin MH; Xu J; Kang BR; Li Y; Lu SM; Zhang SQ Eur J Med Chem; 2015; 96():382-95. PubMed ID: 25911625 [TBL] [Abstract][Full Text] [Related]
13. Design and Discovery of Quinazoline- and Thiourea-Containing Sorafenib Analogs as EGFR and VEGFR-2 Dual TK Inhibitors. Sun S; Zhang J; Wang N; Kong X; Fu F; Wang H; Yao J Molecules; 2017 Dec; 23(1):. PubMed ID: 29295519 [TBL] [Abstract][Full Text] [Related]
14. Discovery of quinazolin-4-amines bearing benzimidazole fragments as dual inhibitors of c-Met and VEGFR-2. Shi L; Wu TT; Wang Z; Xue JY; Xu YG Bioorg Med Chem; 2014 Sep; 22(17):4735-44. PubMed ID: 25082515 [TBL] [Abstract][Full Text] [Related]
15. Inhibition of tumor cell growth and angiogenesis by 7-aminoalkoxy-4-aryloxy-quinazoline ureas, a novel series of multi-tyrosine kinase inhibitors. Ravez S; Barczyk A; Six P; Cagnon A; Garofalo A; Goossens L; Depreux P Eur J Med Chem; 2014 May; 79():369-81. PubMed ID: 24747748 [TBL] [Abstract][Full Text] [Related]
16. Design, synthesis, anti-tumor activity, and molecular modeling of quinazoline and pyrido[2,3-d]pyrimidine derivatives targeting epidermal growth factor receptor. Hou J; Wan S; Wang G; Zhang T; Li Z; Tian Y; Yu Y; Wu X; Zhang J Eur J Med Chem; 2016 Aug; 118():276-89. PubMed ID: 27132165 [TBL] [Abstract][Full Text] [Related]
17. Novel 5-anilinoquinazoline-8-nitro derivatives as inhibitors of VEGFR-2 tyrosine kinase: synthesis, biological evaluation and molecular docking. Xi L; Zhang JQ; Liu ZC; Zhang JH; Yan JF; Jin Y; Lin J Org Biomol Chem; 2013 Jul; 11(26):4367-78. PubMed ID: 23715382 [TBL] [Abstract][Full Text] [Related]
18. Design and discovery of 4-anilinoquinazoline-acylamino derivatives as EGFR and VEGFR-2 dual TK inhibitors. Zhang HQ; Gong FH; Li CG; Zhang C; Wang YJ; Xu YG; Sun LP Eur J Med Chem; 2016 Feb; 109():371-9. PubMed ID: 26826581 [TBL] [Abstract][Full Text] [Related]
19. Potential of substituted quinazolines to interact with multiple targets in the treatment of cancer. Choudhary S; Doshi A; Luckett-Chastain L; Ihnat M; Hamel E; Mooberry SL; Gangjee A Bioorg Med Chem; 2021 Apr; 35():116061. PubMed ID: 33647840 [TBL] [Abstract][Full Text] [Related]