These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

163 related articles for article (PubMed ID: 28407397)

  • 1. Whole-protein alanine-scanning mutagenesis of allostery: A large percentage of a protein can contribute to mechanism.
    Tang Q; Fenton AW
    Hum Mutat; 2017 Sep; 38(9):1132-1143. PubMed ID: 28407397
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Distinguishing the interactions in the fructose 1,6-bisphosphate binding site of human liver pyruvate kinase that contribute to allostery.
    Ishwar A; Tang Q; Fenton AW
    Biochemistry; 2015 Feb; 54(7):1516-24. PubMed ID: 25629396
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The pH dependence of the allosteric response of human liver pyruvate kinase to fructose-1,6-bisphosphate, ATP, and alanine.
    Fenton AW; Hutchinson M
    Arch Biochem Biophys; 2009 Apr; 484(1):16-23. PubMed ID: 19467627
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Exploring the limits of the usefulness of mutagenesis in studies of allosteric mechanisms.
    Tang Q; Alontaga AY; Holyoak T; Fenton AW
    Hum Mutat; 2017 Sep; 38(9):1144-1154. PubMed ID: 28459139
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The phosphate moiety of phosphoenolpyruvate does NOT contribute to allosteric regulation of liver pyruvate kinase by fructose-1,6-bisphosphate
    Chappell BM; Fenton AW
    Arch Biochem Biophys; 2020 Nov; 695():108633. PubMed ID: 33075302
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Changes in the allosteric site of human liver pyruvate kinase upon activator binding include the breakage of an intersubunit cation-π bond.
    McFarlane JS; Ronnebaum TA; Meneely KM; Chilton A; Fenton AW; Lamb AL
    Acta Crystallogr F Struct Biol Commun; 2019 Jun; 75(Pt 6):461-469. PubMed ID: 31204694
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Functional tunability from a distance: Rheostat positions influence allosteric coupling between two distant binding sites.
    Wu T; Swint-Kruse L; Fenton AW
    Sci Rep; 2019 Nov; 9(1):16957. PubMed ID: 31740686
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Benchmarking predictions of allostery in liver pyruvate kinase in CAGI4.
    Xu Q; Tang Q; Katsonis P; Lichtarge O; Jones D; Bovo S; Babbi G; Martelli PL; Casadio R; Lee GR; Seok C; Fenton AW; Dunbrack RL
    Hum Mutat; 2017 Sep; 38(9):1123-1131. PubMed ID: 28370845
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Kinetic and allosteric consequences of mutations in the subunit and domain interfaces and the allosteric site of yeast pyruvate kinase.
    Fenton AW; Blair JB
    Arch Biochem Biophys; 2002 Jan; 397(1):28-39. PubMed ID: 11747307
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synergistic Allosteric Mechanism of Fructose-1,6-bisphosphate and Serine for Pyruvate Kinase M2 via Dynamics Fluctuation Network Analysis.
    Yang J; Liu H; Liu X; Gu C; Luo R; Chen HF
    J Chem Inf Model; 2016 Jun; 56(6):1184-1192. PubMed ID: 27227511
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ligand-induced conformational changes in wild-type and mutant yeast pyruvate kinase.
    Collins RA; Kelly SM; Price NC; Fothergill-Gilmore LA; Muirhead H
    Protein Eng; 1996 Dec; 9(12):1203-10. PubMed ID: 9010934
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The impact of ions on allosteric functions in human liver pyruvate kinase.
    Fenton AW; Alontaga AY
    Methods Enzymol; 2009; 466():83-107. PubMed ID: 21609859
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A study of the allosteric kinetics of Phycomyces pyruvate kinase as judged by the effect of L-alanine and fructose 1,6-bisphosphate.
    del Valle P; de Arriaga D; Busto F; Soler J
    Biochim Biophys Acta; 1986 Nov; 874(2):193-204. PubMed ID: 3778916
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mutational mimics of allosteric effectors: a genome editing design to validate allosteric drug targets.
    Tang Q; Villar MT; Artigues A; Thyfault JP; Apte U; Zhu H; Peterson KR; Fenton AW
    Sci Rep; 2019 Jun; 9(1):9031. PubMed ID: 31227746
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulation of M2-type pyruvate kinase from human meningioma by allosteric effectors fructose 1,6 diphosphate and L-alanine.
    Mellati AA; Yücel M; Altinörs N; Gündüz U
    Cancer Biochem Biophys; 1992 Oct; 13(1):33-41. PubMed ID: 1343845
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The putative effector-binding site of Leishmania mexicana pyruvate kinase studied by site-directed mutagenesis.
    Hannaert V; Yernaux C; Rigden DJ; Fothergill-Gilmore LA; Opperdoes FR; Michels PA
    FEBS Lett; 2002 Mar; 514(2-3):255-9. PubMed ID: 11943161
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The allosteric regulation of pyruvate kinase by fructose-1,6-bisphosphate.
    Jurica MS; Mesecar A; Heath PJ; Shi W; Nowak T; Stoddard BL
    Structure; 1998 Feb; 6(2):195-210. PubMed ID: 9519410
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mining for allosteric information: natural mutations and positional sequence conservation in pyruvate kinase.
    Pendergrass DC; Williams R; Blair JB; Fenton AW
    IUBMB Life; 2006 Jan; 58(1):31-8. PubMed ID: 16540430
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Distinctive regulatory properties of pyruvate kinase 1 from Aedes aegypti mosquitoes.
    Petchampai N; Murillo-Solano C; Isoe J; Pizarro JC; Scaraffia PY
    Insect Biochem Mol Biol; 2019 Jan; 104():82-90. PubMed ID: 30578824
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Allosteric regulation of human liver pyruvate kinase by peptides that mimic the phosphorylated/dephosphorylated N-terminus.
    Prasannan CB; Tang Q; Fenton AW
    Methods Mol Biol; 2012; 796():335-49. PubMed ID: 22052499
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.