112 related articles for article (PubMed ID: 2840783)
21. Free radical formation and DNA strand breakage during metabolism of diaziquone by NAD(P)H quinone-acceptor oxidoreductase (DT-diaphorase) and NADPH cytochrome c reductase.
Fisher GR; Gutierrez PL
Free Radic Biol Med; 1991; 11(6):597-607. PubMed ID: 1663902
[TBL] [Abstract][Full Text] [Related]
22. DNA strand scission and cross-linking by diaziridinylbenzoquinone (diaziquone) in human cells and relation to cell killing.
Szmigiero L; Erickson LC; Ewig RA; Kohn KW
Cancer Res; 1984 Oct; 44(10):4447-52. PubMed ID: 6467204
[TBL] [Abstract][Full Text] [Related]
23. The lack of correlation between toxicity and free radical formation of two diaziridinyl benzoquinones.
Lea JS; Garner HJ; Butler J; Hoey BM; Ward TH
Biochem Pharmacol; 1988 May; 37(10):2023-5. PubMed ID: 2837220
[TBL] [Abstract][Full Text] [Related]
24. Mechanism for the reductive activation of diaziquone.
Mossoba MM; Alizadeh M; Gutierrez PL
J Pharm Sci; 1985 Dec; 74(12):1249-54. PubMed ID: 4087189
[TBL] [Abstract][Full Text] [Related]
25. Diaziquone as a potential agent for photoirradiation therapy: formation of the semiquinone and hydroxyl radicals by visible light.
Mossoba MM; Gutierrez PL
Biochem Biophys Res Commun; 1985 Oct; 132(1):445-52. PubMed ID: 2998365
[TBL] [Abstract][Full Text] [Related]
26. Free radicals in quinone containing antitumor agents. The nature of the diaziquone (3,6,-diaziridinyl-2,5-bis(carboethoxyamino)-1,4-benzoquinone) free radical.
Gutierrez PL; Bachur NR
Biochim Biophys Acta; 1983 Jul; 758(1):37-41. PubMed ID: 6305426
[TBL] [Abstract][Full Text] [Related]
27. Biochemical activation of AZQ [3,6-diaziridinyl-2,5-bis(carboethoxyamino)-1,4-benzoquinone] to its free radical species.
Gutierrez PL; Friedman RD; Bachur NR
Cancer Treat Rep; 1982 Feb; 66(2):339-42. PubMed ID: 6275990
[TBL] [Abstract][Full Text] [Related]
28. Photosensitization of leukemia L1210 cells with diaziquone.
Kessel D; Thompson P
Cancer Res; 1986 Nov; 46(11):5587-8. PubMed ID: 3756904
[TBL] [Abstract][Full Text] [Related]
29. Trace detection of hydroxyl radicals during the redox cycling of low concentrations of diaziquone: a new approach.
Li B; Blough NV; Gutierrez PL
Free Radic Biol Med; 2000 Sep; 29(6):548-56. PubMed ID: 11025198
[TBL] [Abstract][Full Text] [Related]
30. The role of NAD(P)H:quinone oxidoreductase in quinone-mediated p21 induction in human colon carcinoma cells.
Qiu XB; Cadenas E
Arch Biochem Biophys; 1997 Oct; 346(2):241-51. PubMed ID: 9343371
[TBL] [Abstract][Full Text] [Related]
31. The murine disposition and pharmacokinetics of the antineoplastic agent, diaziquone (NSC 182986).
Spiegel JF; Egorin MJ; Collins JM; Lerner BD; Bachur NR
Drug Metab Dispos; 1983; 11(1):41-6. PubMed ID: 6132794
[TBL] [Abstract][Full Text] [Related]
32. Reductive metabolism of diaziquone (AZQ) in the S9 fraction of MCF-7 cells. II. Enhancement of the alkylating activity of AZQ by NAD(P)H: quinone-acceptor oxidoreductase (DT-diaphorase).
Fisher GR; Donis J; Gutierrez PL
Biochem Pharmacol; 1992 Oct; 44(8):1625-35. PubMed ID: 1301071
[TBL] [Abstract][Full Text] [Related]
33. DNA adducts of the antitumor agent diaziquone.
Gupta RC; Garg A; Earley K; Agarwal SC; Lambert GR; Nesnow S
Cancer Res; 1991 Oct; 51(19):5198-204. PubMed ID: 1913643
[TBL] [Abstract][Full Text] [Related]
34. Mitochondrial toxicity of 2,5-diaziridinyl-3,6-bis-(carboethoxyamino)-1,4-benzoquinone.
Oberc-Greenwood MA; Smith BH; Cooke C; Ellis JR; Kornblith PL; McKeever PE
J Natl Cancer Inst; 1983 Oct; 71(4):725-33. PubMed ID: 6578368
[TBL] [Abstract][Full Text] [Related]
35. Diaziquone-induced cytotoxicity in isolated rat hepatocytes.
Silva JM; O'Brien PJ
Cancer Res; 1989 Oct; 49(20):5550-4. PubMed ID: 2790779
[TBL] [Abstract][Full Text] [Related]
36. Effects of ascorbic acid on biologically obtained diaziquone free radicals.
Gutierrez PL; Egorin MJ; Davis TA; Bachur NR
Biochem Pharmacol; 1985 Jul; 34(13):2394-7. PubMed ID: 2990485
[No Abstract] [Full Text] [Related]
37. Phase I-II evaluation of intra-arterial diaziquone for recurrent malignant astrocytomas.
Greenberg HS; Ensminger WD; Layton PB; Gebarski S; Meyer M; Chaffee B; Bender JF; Grillo-Lopez AJ
Cancer Treat Rep; 1986 Mar; 70(3):353-7. PubMed ID: 3006913
[TBL] [Abstract][Full Text] [Related]
38. Diaziquone, 2,5-diaziridinyl-3,6-biscarboethoxyamino-1,4-benzoquinone, plasma and cerebrospinal fluid kinetics.
Bachur NR; Collins JM; Kelley JA; Van Echo DA; Kaplan RS; Whitacre M
Clin Pharmacol Ther; 1982 May; 31(5):650-5. PubMed ID: 7075113
[TBL] [Abstract][Full Text] [Related]
39. Antitumor agents 4. Characterization of free radicals produced during reduction of the antitumor drug 5H-pyridophenoxazin-5-one: an EPR study.
Alberti A; Bolognese A; Guerra M; Lavecchia A; Macciantelli D; Marcaccio M; Novellino E; Paolucci F
Biochemistry; 2003 Oct; 42(41):11924-31. PubMed ID: 14556623
[TBL] [Abstract][Full Text] [Related]
40. Induction of p21 mediated by reactive oxygen species formed during the metabolism of aziridinylbenzoquinones by HCT116 cells.
Qiu X; Forman HJ; Schönthal AH; Cadenas E
J Biol Chem; 1996 Dec; 271(50):31915-21. PubMed ID: 8943236
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]