100 related articles for article (PubMed ID: 28409274)
1. Toward molecular imaging of the free fatty acid receptor 1.
Hellström-Lindahl E; Åberg O; Ericsson C; O'Mahony G; Johnström P; Skrtic S; Eriksson O
Acta Diabetol; 2017 Jul; 54(7):663-668. PubMed ID: 28409274
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and Characterization of a Promising Novel FFAR1/GPR40 Targeting Fluorescent Probe for β-Cell Imaging.
Bertrand R; Wolf A; Ivashchenko Y; Löhn M; Schäfer M; Brönstrup M; Gotthardt M; Derdau V; Plettenburg O
ACS Chem Biol; 2016 Jun; 11(6):1745-54. PubMed ID: 27115176
[TBL] [Abstract][Full Text] [Related]
3. Synthesis of GPR40 targeting
Bertrand R; Hamp I; Brönstrup M; Weck R; Lukacevic M; Polyak A; Ross TL; Gotthardt M; Plettenburg O; Derdau V
J Labelled Comp Radiopharm; 2016 Dec; 59(14):604-610. PubMed ID: 27282912
[TBL] [Abstract][Full Text] [Related]
4. A novel antidiabetic drug, fasiglifam/TAK-875, acts as an ago-allosteric modulator of FFAR1.
Yabuki C; Komatsu H; Tsujihata Y; Maeda R; Ito R; Matsuda-Nagasumi K; Sakuma K; Miyawaki K; Kikuchi N; Takeuchi K; Habata Y; Mori M
PLoS One; 2013; 8(10):e76280. PubMed ID: 24130766
[TBL] [Abstract][Full Text] [Related]
5. FFAR1 is involved in both the acute and chronic effects of palmitate on insulin secretion.
Kristinsson H; Smith DM; Bergsten P; Sargsyan E
Endocrinology; 2013 Nov; 154(11):4078-88. PubMed ID: 24035997
[TBL] [Abstract][Full Text] [Related]
6. Reevaluation of fatty acid receptor 1 as a drug target for the stimulation of insulin secretion in humans.
Wagner R; Kaiser G; Gerst F; Christiansen E; Due-Hansen ME; Grundmann M; Machicao F; Peter A; Kostenis E; Ulven T; Fritsche A; Häring HU; Ullrich S
Diabetes; 2013 Jun; 62(6):2106-11. PubMed ID: 23378609
[TBL] [Abstract][Full Text] [Related]
7. Screening of a novel free fatty acid receptor 1 (FFAR1) agonist peptide by phage display and machine learning based-amino acid substitution.
Yoshioka K; Yamashita H; Shimizu K; Shimomura S; Shibata T; Miyazaki JI; Honda H
Biochem Biophys Res Commun; 2021 Apr; 550():177-183. PubMed ID: 33706101
[TBL] [Abstract][Full Text] [Related]
8. Generating thermostabilized agonist-bound GPR40/FFAR1 using virus-like particles and a label-free binding assay.
Hirozane Y; Motoyaji T; Maru T; Okada K; Tarui N
Mol Membr Biol; 2014 Aug; 31(5):168-75. PubMed ID: 25068810
[TBL] [Abstract][Full Text] [Related]
9. TAK-875, an orally available G protein-coupled receptor 40/free fatty acid receptor 1 agonist, enhances glucose-dependent insulin secretion and improves both postprandial and fasting hyperglycemia in type 2 diabetic rats.
Tsujihata Y; Ito R; Suzuki M; Harada A; Negoro N; Yasuma T; Momose Y; Takeuchi K
J Pharmacol Exp Ther; 2011 Oct; 339(1):228-37. PubMed ID: 21752941
[TBL] [Abstract][Full Text] [Related]
10. Free fatty acid receptor 1 (FFAR1/GPR40) signaling affects insulin secretion by enhancing mitochondrial respiration during palmitate exposure.
Kristinsson H; Bergsten P; Sargsyan E
Biochim Biophys Acta; 2015 Dec; 1853(12):3248-57. PubMed ID: 26408932
[TBL] [Abstract][Full Text] [Related]
11. Current status of GPR40/FFAR1 modulators in medicinal chemistry (2016-2019): a patent review.
Li Z; Zhou Z; Zhang L
Expert Opin Ther Pat; 2020 Jan; 30(1):27-38. PubMed ID: 31771391
[No Abstract] [Full Text] [Related]
12. Stimulation of insulin secretion by acetylenic fatty acids in insulinoma MIN6 cells through FFAR1.
Nishino K; Uesugi H; Hirasawa A; Ohtera A; Miyamae Y; Neffati M; Isoda H; Kambe T; Masuda S; Irie K; Nagao M
Biochem Biophys Res Commun; 2020 Jan; 522(1):68-73. PubMed ID: 31740001
[TBL] [Abstract][Full Text] [Related]
13. Mice Lacking Free Fatty Acid Receptor 1 (GPR40/FFAR1) are Protected Against Conjugated Linoleic Acid-Induced Fatty Liver but Develop Inflammation and Insulin Resistance in the Brain.
Sartorius T; Drescher A; Panse M; Lastovicka P; Peter A; Weigert C; Kostenis E; Ullrich S; Häring HU
Cell Physiol Biochem; 2015; 35(6):2272-84. PubMed ID: 25895678
[TBL] [Abstract][Full Text] [Related]
14. Islet-selectivity of G-protein coupled receptor ligands evaluated for PET imaging of pancreatic β-cell mass.
Cline GW; Zhao X; Jakowski AB; Soeller WC; Treadway JL
Biochem Biophys Res Commun; 2011 Sep; 412(3):413-8. PubMed ID: 21820405
[TBL] [Abstract][Full Text] [Related]
15. High-resolution structure of the human GPR40 receptor bound to allosteric agonist TAK-875.
Srivastava A; Yano J; Hirozane Y; Kefala G; Gruswitz F; Snell G; Lane W; Ivetac A; Aertgeerts K; Nguyen J; Jennings A; Okada K
Nature; 2014 Sep; 513(7516):124-7. PubMed ID: 25043059
[TBL] [Abstract][Full Text] [Related]
16. [The role of brain n-3 fatty acids-GPR40/FFAR1 signaling in pain].
Nakamoto K; Tokuyama S
Nihon Yakurigaku Zasshi; 2018; 151(1):21-26. PubMed ID: 29321392
[TBL] [Abstract][Full Text] [Related]
17. FFAR1/GPR40: One target, different binding sites, many agonists, no drugs, but a continuous and unprofitable tug-of-war between ligand lipophilicity, activity, and toxicity.
Governa P; Caroleo MC; Carullo G; Aiello F; Cione E; Manetti F
Bioorg Med Chem Lett; 2021 Jun; 41():127969. PubMed ID: 33771587
[TBL] [Abstract][Full Text] [Related]
18. Free fatty acid receptor 1: a ray of hope in the therapy of type 2 diabetes mellitus.
Arora A; Behl T; Sehgal A; Singh S; Sharma N; Chigurupati S; Kaur R; Bhatia S; Al-Harrasi A; Vargas-De-La-Cruz C; Bungau S
Inflammopharmacology; 2021 Dec; 29(6):1625-1639. PubMed ID: 34669065
[TBL] [Abstract][Full Text] [Related]
19. Homology modeling and explicit membrane molecular dynamics simulation to delineate the mode of binding of thiazolidinediones into FFAR1 and the mechanism of receptor activation.
Helal MA; Darwish KM; Hammad MA
Bioorg Med Chem Lett; 2014 Nov; 24(22):5330-6. PubMed ID: 25441945
[TBL] [Abstract][Full Text] [Related]
20. Differential free fatty acid receptor-1 (FFAR1/GPR40) signalling is associated with gene expression or gelatinase granule release in bovine neutrophils.
Mena SJ; Manosalva C; Carretta MD; Teuber S; Olmo I; Burgos RA; Hidalgo MA
Innate Immun; 2016 Aug; 22(6):479-89. PubMed ID: 27363707
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]