These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

543 related articles for article (PubMed ID: 28415564)

  • 1. Mammalian sphingosine kinase (SphK) isoenzymes and isoform expression: challenges for SphK as an oncotarget.
    Hatoum D; Haddadi N; Lin Y; Nassif NT; McGowan EM
    Oncotarget; 2017 May; 8(22):36898-36929. PubMed ID: 28415564
    [TBL] [Abstract][Full Text] [Related]  

  • 2. "Dicing and Splicing" Sphingosine Kinase and Relevance to Cancer.
    Haddadi N; Lin Y; Simpson AM; Nassif NT; McGowan EM
    Int J Mol Sci; 2017 Sep; 18(9):. PubMed ID: 28869494
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Extracellular export of sphingosine kinase-1a contributes to the vascular S1P gradient.
    Venkataraman K; Thangada S; Michaud J; Oo ML; Ai Y; Lee YM; Wu M; Parikh NS; Khan F; Proia RL; Hla T
    Biochem J; 2006 Aug; 397(3):461-71. PubMed ID: 16623665
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sphingosine kinase inhibitors: A patent review.
    Cao M; Ji C; Zhou Y; Huang W; Ni W; Tong X; Wei JF
    Int J Mol Med; 2018 May; 41(5):2450-2460. PubMed ID: 29484372
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Importance of sphingosine kinase (SphK) as a target in developing cancer therapeutics and recent developments in the synthesis of novel SphK inhibitors.
    Plano D; Amin S; Sharma AK
    J Med Chem; 2014 Jul; 57(13):5509-24. PubMed ID: 24471412
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeting Sphingosine Kinase Isoforms Effectively Reduces Growth and Survival of Neoplastic Mast Cells With D816V-KIT.
    Bandara G; Muñoz-Cano R; Tobío A; Yin Y; Komarow HD; Desai A; Metcalfe DD; Olivera A
    Front Immunol; 2018; 9():631. PubMed ID: 29643855
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sphingosine kinase (SphK) 1 and SphK2 play equivalent roles in mediating insulin's mitogenic action.
    Dai L; Qi Y; Chen J; Kaczorowski D; Di W; Wang W; Xia P
    Mol Endocrinol; 2014 Feb; 28(2):197-207. PubMed ID: 24422628
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Neuroprotective role of sphingolipid rheostat in excitotoxic retinal ganglion cell death.
    Nakamura N; Honjo M; Yamagishi R; Kurano M; Yatomi Y; Watanabe S; Aihara M
    Exp Eye Res; 2021 Jul; 208():108623. PubMed ID: 34022173
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Usage of sphingosine kinase isoforms in mast cells is species and/or cell type determined.
    Dillahunt SE; Sargent JL; Suzuki R; Proia RL; Gilfillan A; Rivera J; Olivera A
    J Immunol; 2013 Mar; 190(5):2058-67. PubMed ID: 23359503
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design of Sphingosine Kinases Inhibitors: Challenges and Recent Developments.
    Magli E; Corvino A; Fiorino F; Frecentese F; Perissutti E; Saccone I; Santagada V; Caliendo G; Severino B
    Curr Pharm Des; 2019; 25(9):956-968. PubMed ID: 30947653
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Rational design of SphK inhibitors using crystal structures aided by computer.
    Ding T; Zhi Y; Xie W; Yao Q; Liu B
    Eur J Med Chem; 2021 Mar; 213():113164. PubMed ID: 33454547
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeting SphK1 as a new strategy against cancer.
    Shida D; Takabe K; Kapitonov D; Milstien S; Spiegel S
    Curr Drug Targets; 2008 Aug; 9(8):662-73. PubMed ID: 18691013
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Anti-inflammatory effects of sphingosine kinase modulation in inflammatory arthritis.
    Lai WQ; Irwan AW; Goh HH; Howe HS; Yu DT; Valle-Oñate R; McInnes IB; Melendez AJ; Leung BP
    J Immunol; 2008 Dec; 181(11):8010-7. PubMed ID: 19017993
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation and functional roles of sphingosine kinases.
    Alemany R; van Koppen CJ; Danneberg K; Ter Braak M; Meyer Zu Heringdorf D
    Naunyn Schmiedebergs Arch Pharmacol; 2007 Feb; 374(5-6):413-28. PubMed ID: 17242884
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The sphingosine kinase-1/sphingosine-1-phosphate axis in cancer: Potential target for anticancer therapy.
    Zheng X; Li W; Ren L; Liu J; Pang X; Chen X; Kang D; Wang J; Du G
    Pharmacol Ther; 2019 Mar; 195():85-99. PubMed ID: 30347210
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure guided design of a series of sphingosine kinase (SphK) inhibitors.
    Gustin DJ; Li Y; Brown ML; Min X; Schmitt MJ; Wanska M; Wang X; Connors R; Johnstone S; Cardozo M; Cheng AC; Jeffries S; Franks B; Li S; Shen S; Wong M; Wesche H; Xu G; Carlson TJ; Plant M; Morgenstern K; Rex K; Schmitt J; Coxon A; Walker N; Kayser F; Wang Z
    Bioorg Med Chem Lett; 2013 Aug; 23(16):4608-16. PubMed ID: 23845219
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sphingosine kinase and sphingosine-1-phosphate receptor signaling pathway in inflammatory gastrointestinal disease and cancers: A novel therapeutic target.
    Sukocheva OA; Furuya H; Ng ML; Friedemann M; Menschikowski M; Tarasov VV; Chubarev VN; Klochkov SG; Neganova ME; Mangoni AA; Aliev G; Bishayee A
    Pharmacol Ther; 2020 Mar; 207():107464. PubMed ID: 31863815
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sphingosine kinases are not required for inflammatory responses in macrophages.
    Xiong Y; Lee HJ; Mariko B; Lu YC; Dannenberg AJ; Haka AS; Maxfield FR; Camerer E; Proia RL; Hla T
    J Biol Chem; 2013 Nov; 288(45):32563-32573. PubMed ID: 24081141
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Therapeutic potential of targeting sphingosine kinases and sphingosine 1-phosphate in hematological malignancies.
    Evangelisti C; Evangelisti C; Buontempo F; Lonetti A; Orsini E; Chiarini F; Barata JT; Pyne S; Pyne NJ; Martelli AM
    Leukemia; 2016 Nov; 30(11):2142-2151. PubMed ID: 27461062
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sphingosine kinase inhibitors: a review of patent literature (2006-2015).
    Lynch KR; Thorpe SB; Santos WL
    Expert Opin Ther Pat; 2016 Dec; 26(12):1409-1416. PubMed ID: 27539678
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 28.