BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

319 related articles for article (PubMed ID: 28415741)

  • 1. Enhancement of radiosensitivity by the novel anticancer quinolone derivative vosaroxin in preclinical glioblastoma models.
    Gravina GL; Mancini A; Mattei C; Vitale F; Marampon F; Colapietro A; Rossi G; Ventura L; Vetuschi A; Di Cesare E; Fox JA; Festuccia C
    Oncotarget; 2017 May; 8(18):29865-29886. PubMed ID: 28415741
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Radiosensitization by the novel DNA intercalating agent vosaroxin.
    Gordon IK; Graves C; Kil WJ; Kramp T; Tofilon P; Camphausen K
    Radiat Oncol; 2012 Feb; 7():26. PubMed ID: 22369205
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The first-in-class alkylating deacetylase inhibitor molecule tinostamustine shows antitumor effects and is synergistic with radiotherapy in preclinical models of glioblastoma.
    Festuccia C; Mancini A; Colapietro A; Gravina GL; Vitale F; Marampon F; Delle Monache S; Pompili S; Cristiano L; Vetuschi A; Tombolini V; Chen Y; Mehrling T
    J Hematol Oncol; 2018 Feb; 11(1):32. PubMed ID: 29486795
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The DNA-PK Inhibitor VX-984 Enhances the Radiosensitivity of Glioblastoma Cells Grown
    Timme CR; Rath BH; O'Neill JW; Camphausen K; Tofilon PJ
    Mol Cancer Ther; 2018 Jun; 17(6):1207-1216. PubMed ID: 29549168
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Anticancer Non-narcotic Opium Alkaloid Papaverine Suppresses Human Glioblastoma Cell Growth.
    Inada M; Sato A; Shindo M; Yamamoto Y; Akasaki Y; Ichimura K; Tanuma SI
    Anticancer Res; 2019 Dec; 39(12):6743-6750. PubMed ID: 31810939
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Trifluoperazine, a novel autophagy inhibitor, increases radiosensitivity in glioblastoma by impairing homologous recombination.
    Zhang X; Xu R; Zhang C; Xu Y; Han M; Huang B; Chen A; Qiu C; Thorsen F; Prestegarden L; Bjerkvig R; Wang J; Li X
    J Exp Clin Cancer Res; 2017 Sep; 36(1):118. PubMed ID: 28870216
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Increased cure rate of glioblastoma using concurrent therapy with radiotherapy and arsenic trioxide.
    Ning S; Knox SJ
    Int J Radiat Oncol Biol Phys; 2004 Sep; 60(1):197-203. PubMed ID: 15337556
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The preclinical discovery of vosaroxin for the treatment of acute myeloid leukemia.
    Paubelle E; Zylbersztejn F; Thomas X
    Expert Opin Drug Discov; 2017 Jul; 12(7):747-753. PubMed ID: 28504025
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Telomerase inhibition improves tumor response to radiotherapy in a murine orthotopic model of human glioblastoma.
    Ferrandon S; Malleval C; El Hamdani B; Battiston-Montagne P; Bolbos R; Langlois JB; Manas P; Gryaznov SM; Alphonse G; Honnorat J; Rodriguez-Lafrasse C; Poncet D
    Mol Cancer; 2015 Jul; 14():134. PubMed ID: 26183089
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dual mTORC1/2 blockade inhibits glioblastoma brain tumor initiating cells in vitro and in vivo and synergizes with temozolomide to increase orthotopic xenograft survival.
    Luchman HA; Stechishin OD; Nguyen SA; Lun XQ; Cairncross JG; Weiss S
    Clin Cancer Res; 2014 Nov; 20(22):5756-67. PubMed ID: 25316808
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular and Pharmacologic Properties of the Anticancer Quinolone Derivative Vosaroxin: A New Therapeutic Agent for Acute Myeloid Leukemia.
    Jamieson GC; Fox JA; Poi M; Strickland SA
    Drugs; 2016 Sep; 76(13):1245-1255. PubMed ID: 27484675
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Protein Phosphatase 2A Inhibition with LB100 Enhances Radiation-Induced Mitotic Catastrophe and Tumor Growth Delay in Glioblastoma.
    Gordon IK; Lu J; Graves CA; Huntoon K; Frerich JM; Hanson RH; Wang X; Hong CS; Ho W; Feldman MJ; Ikejiri B; Bisht K; Chen XS; Tandle A; Yang C; Arscott WT; Ye D; Heiss JD; Lonser RR; Camphausen K; Zhuang Z
    Mol Cancer Ther; 2015 Jul; 14(7):1540-1547. PubMed ID: 25939762
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Voreloxin, formerly SNS-595, has potent activity against a broad panel of cancer cell lines and in vivo tumor models.
    Hoch U; Lynch J; Sato Y; Kashimoto S; Kajikawa F; Furutani Y; Silverman JA
    Cancer Chemother Pharmacol; 2009 Jun; 64(1):53-65. PubMed ID: 18931998
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The Efficacy of the Wee1 Inhibitor MK-1775 Combined with Temozolomide Is Limited by Heterogeneous Distribution across the Blood-Brain Barrier in Glioblastoma.
    Pokorny JL; Calligaris D; Gupta SK; Iyekegbe DO; Mueller D; Bakken KK; Carlson BL; Schroeder MA; Evans DL; Lou Z; Decker PA; Eckel-Passow JE; Pucci V; Ma B; Shumway SD; Elmquist WF; Agar NY; Sarkaria JN
    Clin Cancer Res; 2015 Apr; 21(8):1916-24. PubMed ID: 25609063
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Blockade of TGF-β signaling by the TGFβR-I kinase inhibitor LY2109761 enhances radiation response and prolongs survival in glioblastoma.
    Zhang M; Kleber S; Röhrich M; Timke C; Han N; Tuettenberg J; Martin-Villalba A; Debus J; Peschke P; Wirkner U; Lahn M; Huber PE
    Cancer Res; 2011 Dec; 71(23):7155-67. PubMed ID: 22006998
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Epidermal growth factor receptor expression modulates antitumor efficacy of vandetanib or cediranib combined with radiotherapy in human glioblastoma xenografts.
    Wachsberger PR; Lawrence YR; Liu Y; Daroczi B; Xu X; Dicker AP
    Int J Radiat Oncol Biol Phys; 2012 Jan; 82(1):483-91. PubMed ID: 21095630
    [TBL] [Abstract][Full Text] [Related]  

  • 17. OTX015 (MK-8628), a novel BET inhibitor, displays in vitro and in vivo antitumor effects alone and in combination with conventional therapies in glioblastoma models.
    Berenguer-Daizé C; Astorgues-Xerri L; Odore E; Cayol M; Cvitkovic E; Noel K; Bekradda M; MacKenzie S; Rezai K; Lokiec F; Riveiro ME; Ouafik L
    Int J Cancer; 2016 Nov; 139(9):2047-55. PubMed ID: 27388964
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Venetoclax Synergistically Enhances the Anti-leukemic Activity of Vosaroxin Against Acute Myeloid Leukemia Cells Ex Vivo.
    Liu F; Knight T; Su Y; Edwards H; Wang G; Wang Y; Taub JW; Lin H; Sun L; Ge Y
    Target Oncol; 2019 Jun; 14(3):351-364. PubMed ID: 31115744
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Homologous recombination repair is essential for repair of vosaroxin-induced DNA double-strand breaks.
    Hawtin RE; Stockett DE; Wong OK; Lundin C; Helleday T; Fox JA
    Oncotarget; 2010 Nov; 1(7):606-619. PubMed ID: 21317456
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Vosaroxin induces mitochondrial dysfunction and apoptosis in cervical cancer HeLa cells: Involvement of AMPK/Sirt3/HIF-1 pathway.
    Zhao XL; Yu CZ
    Chem Biol Interact; 2018 Jun; 290():57-63. PubMed ID: 29800573
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.