BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

179 related articles for article (PubMed ID: 28416419)

  • 1. Evaluation of Renal Transporter Inhibition Using Creatinine as a Substrate In Vitro to Assess the Clinical Risk of Elevated Serum Creatinine.
    Mathialagan S; Rodrigues AD; Feng B
    J Pharm Sci; 2017 Sep; 106(9):2535-2541. PubMed ID: 28416419
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Complexities of Interpreting Reversible Elevated Serum Creatinine Levels in Drug Development: Does a Correlation with Inhibition of Renal Transporters Exist?
    Chu X; Bleasby K; Chan GH; Nunes I; Evers R
    Drug Metab Dispos; 2016 Sep; 44(9):1498-509. PubMed ID: 26825641
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Contribution of the organic anion transporter OAT2 to the renal active tubular secretion of creatinine and mechanism for serum creatinine elevations caused by cobicistat.
    Lepist EI; Zhang X; Hao J; Huang J; Kosaka A; Birkus G; Murray BP; Bannister R; Cihlar T; Huang Y; Ray AS
    Kidney Int; 2014 Aug; 86(2):350-7. PubMed ID: 24646860
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tucatinib Inhibits Renal Transporters OCT2 and MATE Without Impacting Renal Function in Healthy Subjects.
    Topletz-Erickson AR; Lee AJ; Mayor JG; Rustia EL; Abdulrasool LI; Wise AL; Dailey B; DeChenne S; Walker LN; Alley SC; Endres CJ
    J Clin Pharmacol; 2021 Apr; 61(4):461-471. PubMed ID: 32989831
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Fampridine is a Substrate and Inhibitor of Human OCT2, but not of Human MATE1, or MATE2K.
    Xiao G; Rowbottom C; Boiselle C; Gan LS
    Pharm Res; 2018 Jun; 35(8):159. PubMed ID: 29915999
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Quantitative Consideration of Clinical Increases in Serum Creatinine Caused by Renal Transporter Inhibition.
    Nakada T; Kudo T; Ito K
    Drug Metab Dispos; 2023 Sep; 51(9):1114-1126. PubMed ID: 36859345
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Prediction of clinical drug-drug interactions of veliparib (ABT-888) with human renal transporters (OAT1, OAT3, OCT2, MATE1, and MATE2K).
    Kikuchi R; Lao Y; Bow DA; Chiou WJ; Andracki ME; Carr RA; Voorman RL; De Morais SM
    J Pharm Sci; 2013 Dec; 102(12):4426-32. PubMed ID: 24122511
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Renal secretion of hydrochlorothiazide involves organic anion transporter 1/3, organic cation transporter 2, and multidrug and toxin extrusion protein 2-K.
    Yin J; Wagner DJ; Prasad B; Isoherranen N; Thummel KE; Wang J
    Am J Physiol Renal Physiol; 2019 Oct; 317(4):F805-F814. PubMed ID: 31322418
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Impact of Substrate-Dependent Inhibition on Renal Organic Cation Transporters hOCT2 and hMATE1/2-K-Mediated Drug Transport and Intracellular Accumulation.
    Yin J; Duan H; Wang J
    J Pharmacol Exp Ther; 2016 Dec; 359(3):401-410. PubMed ID: 27758931
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Changes of drug pharmacokinetics mediated by downregulation of kidney organic cation transporters Mate1 and Oct2 in a rat model of hyperuricemia.
    Nishizawa K; Yoda N; Morokado F; Komori H; Nakanishi T; Tamai I
    PLoS One; 2019; 14(4):e0214862. PubMed ID: 30951542
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Significance of Organic Anion Transporter 2 and Organic Cation Transporter 2 in Creatinine Clearance: Mechanistic Evaluation Using Freshly Prepared Human Primary Renal Proximal Tubule Cells.
    Mathialagan S; Chung G; Pye K; Rodrigues AD; Varma MVS; Brown C
    J Pharmacol Exp Ther; 2024 Jan; 388(1):201-208. PubMed ID: 37977812
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Characterization of Organic Anion Transporter 2 (SLC22A7): A Highly Efficient Transporter for Creatinine and Species-Dependent Renal Tubular Expression.
    Shen H; Liu T; Morse BL; Zhao Y; Zhang Y; Qiu X; Chen C; Lewin AC; Wang XT; Liu G; Christopher LJ; Marathe P; Lai Y
    Drug Metab Dispos; 2015 Jul; 43(7):984-93. PubMed ID: 25904762
    [TBL] [Abstract][Full Text] [Related]  

  • 13. No Inhibition of MATE1/2K-Mediated Renal Creatinine Secretion Predicted With Ritonavir or Cobicistat.
    Kikuchi R; Chiou WJ; Kasai MA; de Morais SM; Bow DAJ
    J Pharm Sci; 2019 Sep; 108(9):3118-3123. PubMed ID: 31034908
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Estimation of changes in serum creatinine and creatinine clearance caused by renal transporter inhibition in healthy subjects.
    Nakada T; Kudo T; Kume T; Kusuhara H; Ito K
    Drug Metab Pharmacokinet; 2019 Aug; 34(4):233-238. PubMed ID: 31176593
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Impact on creatinine renal clearance by the interplay of multiple renal transporters: a case study with INCB039110.
    Zhang Y; Warren MS; Zhang X; Diamond S; Williams B; Punwani N; Huang J; Huang Y; Yeleswaram S
    Drug Metab Dispos; 2015 Apr; 43(4):485-9. PubMed ID: 25605813
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Renal Excretion of Dabigatran: The Potential Role of Multidrug and Toxin Extrusion (MATE) Proteins.
    Shen H; Yao M; Sinz M; Marathe P; Rodrigues AD; Zhu M
    Mol Pharm; 2019 Sep; 16(9):4065-4076. PubMed ID: 31335150
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Assessment of vandetanib as an inhibitor of various human renal transporters: inhibition of multidrug and toxin extrusion as a possible mechanism leading to decreased cisplatin and creatinine clearance.
    Shen H; Yang Z; Zhao W; Zhang Y; Rodrigues AD
    Drug Metab Dispos; 2013 Dec; 41(12):2095-103. PubMed ID: 24026623
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pregnancy Increases the Renal Secretion of N
    Bergagnini-Kolev MC; Hebert MF; Easterling TR; Lin YS
    Drug Metab Dispos; 2017 Mar; 45(3):325-329. PubMed ID: 28069720
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Atenolol Renal Secretion Is Mediated by Human Organic Cation Transporter 2 and Multidrug and Toxin Extrusion Proteins.
    Yin J; Duan H; Shirasaka Y; Prasad B; Wang J
    Drug Metab Dispos; 2015 Dec; 43(12):1872-81. PubMed ID: 26374172
    [TBL] [Abstract][Full Text] [Related]  

  • 20. N(1)-methylnicotinamide as an endogenous probe for drug interactions by renal cation transporters: studies on the metformin-trimethoprim interaction.
    Müller F; Pontones CA; Renner B; Mieth M; Hoier E; Auge D; Maas R; Zolk O; Fromm MF
    Eur J Clin Pharmacol; 2015 Jan; 71(1):85-94. PubMed ID: 25552403
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.